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Volumn 79, Issue C, 2009, Pages 721-738

Stereocontrolled total synthesis of (±)-FR901483

Author keywords

FR901483; Intramolecular Aldol Reaction; One Electron Reduction; Stereocontrolled Reaction; Tricyclic Skeleton

Indexed keywords


EID: 67651083664     PISSN: 03855414     EISSN: None     Source Type: Journal    
DOI: 10.3987/COM-08-S(D)38     Document Type: Article
Times cited : (14)

References (33)
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    • For a review of biomimetic synthesis of this family compounds, see
    • For a review of biomimetic synthesis of this family compounds, see. Takayama H. J. Synth. Org. Chem. Jpn. 60 (2002) 350
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    • For total syntheses, see. Snider B.B., and Lin H. J. Am. Chem. Soc. 121 (1999) 7778
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    • Snider, B.B.1    Lin, H.2
  • 22
    • 67651137398 scopus 로고    scopus 로고
    • We are in the process of publishing the formal total synthesis of (-)-FR901483 using Ugi reaction, which was investigated independently of 3m.
    • We are in the process of publishing the formal total synthesis of (-)-FR901483 using Ugi reaction, which was investigated independently of 3m.
  • 23
    • 33746442416 scopus 로고    scopus 로고
    • For a review on enantioselective desymmetrization, see
    • For a review on enantioselective desymmetrization, see. Willis M.C. Perkin Trans. 1 13 (1999) 1765
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    • note
    • For a similar reaction, see ref 4d.
  • 26
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    • note
    • A synthetic protocol based on a NaBH(OAc)3 reduction and selective deprotection of the TBS ether has already been reported in ref 4d. However, transformation of 5 to 18 has been developed independently in our laboratory, see ref 3a.
  • 27
    • 0033550194 scopus 로고    scopus 로고
    • A similar enhancement of the mono-alkylation reaction by the addition of alkyl amine derivatives has been reported, see
    • A similar enhancement of the mono-alkylation reaction by the addition of alkyl amine derivatives has been reported, see. Goto M., Akimoto K., Aoki K., Shindo M., and Koga K. Tetrahedron Lett. 40 (1999) 8129
    • (1999) Tetrahedron Lett. , vol.40 , pp. 8129
    • Goto, M.1    Akimoto, K.2    Aoki, K.3    Shindo, M.4    Koga, K.5
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    • 2, by the addition of HMPA has been reported, see
    • 2, by the addition of HMPA has been reported, see. Inanaga J., and Yamaguchi M. J. Synth. Org. Chem. Jpn. 47 (1989) 200
    • (1989) J. Synth. Org. Chem. Jpn. , vol.47 , pp. 200
    • Inanaga, J.1    Yamaguchi, M.2
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    • For a review of the phosphoramidite method, see
    • For a review of the phosphoramidite method, see. Iyer R.P. Tetrahedron 48 (1992) 2223
    • (1992) Tetrahedron , vol.48 , pp. 2223
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    • note
    • For a similar regioselective phosphorylation, see 4a.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.