Synthetic studies towards bioactive frondosins: rapid framework access and diversity creation

Tetrahedron Letters

Volumn 50, Issue 37, 2009, Pages 5263-5266

  Mehta, Goverdhan ^a   Likhite, Nachiket S ^a  

^a INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

FRONDOSIN DERIVATIVE; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS; STRUCTURE ANALYSIS;

EID: 67651039798     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2009.07.021     Document Type: Article

References (23)

1. Patil A.D., Freyer A.J., Killmer L., Offen P., Carte B., Jurewicz A.J., and Johnson R.K. Tetrahedron 53 (1997) 5047-5060
2. Hallock Y.F., Cardellina II J.H., and Boyd M.R. Nat. Prod. Lett. 11 (1998) 153-160
3. Seitz M., Dewald B., Gerber N., and Baggiolini M. J. Clin. Invest. 87 (1991) 463-469
4. Miller E.J., Cohen A.B., Nagao D., Griffith R.J., Maunder R.J., Martin T.R., Weiner-Kronish J.P., Sticherling M., Christophers E., and Matthay M.A. Am. Rev. Respir. Dis. 146 (1992) 427-432
5. Brat D.J., Bellail A.C., and Van Meir E.G. Neurooncology 7 (2005) 122-133
6. Zhu Y.M., Webster S.J., Flower D., and Woll P.J. Br. J. Cancer 91 (2004) 1970-1976
7. Inoue M., Frontier A.J., and Danishefsky S.J. Angew. Chem., Int. Ed. 39 (2000) 761-764
8. Inoue M., Carson M.W., Frontier A.J., and Danishefsky S.J. J. Am. Chem. Soc. 123 (2001) 1878-1889
9. Hughes C.C., and Trauner D. Angew. Chem., Int. Ed. 41 (2002) 1569-1572
10. Hughes C.C., and Trauner D. Tetrahedron 60 (2004) 9675-9686
11. Kerr D.J., Willis A.C., and Flynn B.L. Org. Lett. 6 (2004) 457-460
12. Masters K.-S., and Flynn B.L. J. Org. Chem. 73 (2008) 8081-8084
13. Li X., and Ovaska T.V. Org. Lett. 9 (2007) 3837-3840
14. Li X., Kyne R.E., and Ovaska T.V. Tetrahedron 63 (2007) 1899-1906
15. Li X., Keon A.E., Sullivan J.A., and Ovaska T.V. Org. Lett. 10 (2008) 3287-3290
16. Trost B.M., Hu Y., and Horne D.B. J. Am. Chem. Soc. 129 (2007) 11781-11790
17. Oslon J.P., and Davies H.M.L. Org. Lett. 10 (2008) 573-576
18. Mehta G., and Likhite N.S. Tetrahedron Lett. 49 (2008) 7113-7116
19. 3): δ 6.65 (s, 1H), 6.49 (s, 1H), 6.15-6.14 (m, 1H), 5.74-5.67 (m, 1H), 3.87 (s, 3H), 3.85 (s, 3H), 3.78 (s, 3H), 2.91 (br s, 1H), 2.66 (br s, 1H), 2.58 (dd, J = 14.1, 8.4 Hz, 1H), 2.48-2.41
20. Yadav J.S., Reddy B.V.S., Sadasiv K., and Satheesh G. Tetrahedron Lett. 43 (2002) 9695-9697
21. -1, number of l.s. parameters = 479, R1 = 0.129 for 4799 reflections with I > 2σ(I) and 0.167 for all 7181 data, wR2 = 0.374, GOF = 1.432 for all data.
22. Schultz A.G., Taveras A.G., and Harrington R.E. Tetrahedron Lett. 29 (1988) 3907-3910
23. Pearson A.J., Chen Y.-S., Hsu S.-Y., and Ray T. Tetrahedron Lett. 25 (1984) 1235-1238