Acetaminophen safety - Déjà Vu

Medical Letter on Drugs and Therapeutics

Volumn 51, Issue 1316, 2009, Pages

[No Author Info available]

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; AMINOTRANSFERASE; ANALGESIC AGENT; ANTITUSSIVE AGENT; CINNAMEDRINE; CODEINE; COMTREX; CONSTITUTIVE ANDROSTANE RECEPTOR; CORICIDIN; DEXTROPROPOXYPHENE; DEXTROPROPOXYPHENE NAPSILATE; DOXYLAMINE; DRUG METABOLITE; EXCEDRIN; GLUTATHIONE; GOODYS BODY PAIN; GUAIFENESIN; HYDROCODONE BITARTRATE PLUS PARACETAMOL; N ACETYL 4 BENZOQUINONEIMINE; NOREPHEDRINE; PARACETAMOL; PARACETAMOL PLUS PENTAZOCINE; PARACETAMOL PLUS TRAMADOL; PERCOCET; PERCOGESIC; PSEUDOEPHEDRINE; ROXICET; SINUTAB; THERAFLU; TRIAMINIC; UNCLASSIFIED DRUG; VANQUISH; VICKS;

ALCOHOL CONSUMPTION; ALCOHOLISM; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG LABELING; DRUG MEGADOSE; DRUG OVERDOSE; DRUG OXIDATION; DRUG SAFETY; HEADACHE; HUMAN; LIVER INJURY; LIVER NECROSIS; LIVER TOXICITY; OSTEOARTHRITIS; POSTOPERATIVE PAIN; RECOMMENDED DRUG DOSE; RISK FACTOR; SHORT SURVEY; ADULT; ARTICLE; CHEMICALLY INDUCED DISORDER; DRUG COMBINATION; FOOD AND DRUG ADMINISTRATION; LIVER DISEASE; PAIN; RISK ASSESSMENT; SAFETY; UNITED STATES;

ACETAMINOPHEN; ADULT; ANALGESICS, NON-NARCOTIC; CONSUMER PRODUCT SAFETY; DRUG COMBINATIONS; DRUG LABELING; HUMANS; LIVER DISEASES; PAIN; RISK ASSESSMENT; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 67651018111     PISSN: 0025732X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey

References (8)

1. www.fda.gov, search "acetaminophen hepatotoxicity." Accessed October 2002.
2. HJ McQuay et al. Evaluating analgesia: the challenges. Am J Ther 2002; 9:179.
3. PB Watkins et al. Aminotransferase elevations in healthy adults receiving 4 grams of acetaminophen daily: a randomized controlled trial. JAMA 2006; 296:87.
4. J Zhang et al. Modulation of acetaminophen-induced hepatotoxicity by the xenobiotic receptor CAR. Science 2002; 298:422.
5. NA Buckley and J Srinivasan. Should a lower treatment line be used when treating paracetamol poisoning in patients with chronic alcoholism?: a case for. Drug Saf 2002; 25:619.
6. BL Strom. Adverse reactions to over-the-counter analgesics taken for therapeutic purposes. JAMA 1994; 272:1866.
7. LF Prescott. Paracetamol, alcohol and the liver. Br J Clin Pharmacol 2000; 49:291.
8. EK Kuffner et al. Effect of maximal daily doses of acetaminophen on the liver of alcoholic patients: a randomized, double-blind, placebo-controlled trial. Arch Intern Med 2001; 161:2247.