Mice with disrupted TGFβ signaling have normal cerebella development, but exhibit facial dysmorphogenesis and strain-dependent deficits in their body wall

Cellular and Molecular Neurobiology

Volumn 29, Issue 5, 2009, Pages 621-633

  Asano, Yoshiya ^a,b   Koishi, Kyoko ^a   Frugier, Tony ^a,c   McLennan, Ian S ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

^b HIROSAKI UNIVERSITY   (Japan)

^c ALFRED HOSPITAL   (Australia)

Author keywords

Development; Dominant negative inhibitor; Modifier gene; Mouse model; Neuron; Transforming growth factor beta

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA; DOXYCYCLINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN SIZE; C57BL 6 MOUSE; CEREBELLUM; CONTROLLED STUDY; EMBRYO; EMBRYO DEVELOPMENT; FACE DYSMORPHOGENESIS; FACE MALFORMATION; FACIAL BONE; FEMALE; GENE DISRUPTION; GENE EXPRESSION; GENETIC VARIABILITY; GENETICS; HISTOLOGY; IMMUNOHISTOCHEMISTRY; INTESTINE; INTESTINE MOTILITY; MOUSE; NERVE CELL; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; STEREOLOGY; TRANSGENE; ABDOMEN; ANIMAL; ANIMAL EMBRYO; CONGENITAL MALFORMATION; CROSS BREEDING; DRUG EFFECT; EMBRYO DEATH; FACE; GENE EXPRESSION REGULATION; MALE; METABOLISM; MOUSE STRAIN; PATHOLOGY; PRENATAL DEVELOPMENT; SIGNAL TRANSDUCTION; SURVIVAL;

EPICOCCUM; MUS;

ABDOMEN; ANIMALS; CEREBELLUM; CROSSES, GENETIC; DOXYCYCLINE; EMBRYO LOSS; EMBRYO, MAMMALIAN; FACE; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; MALE; MICE; MICE, INBRED STRAINS; PHENOTYPE; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; TRANSFORMING GROWTH FACTOR BETA; TRANSGENES;

EID: 67650901990     PISSN: 02724340     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10571-009-9354-x     Document Type: Article

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