Inhibition of ataxia-telangiectasia mutated by antisense oligonucleotide nanoparticles induces radiosensitization of head and neck squamous-cell carcinoma in mice

Cancer Biotherapy and Radiopharmaceuticals

Volumn 24, Issue 3, 2009, Pages 339-346

  Zou, Jian ^a   Qiao, Xiaoming ^a   Ye, Huiping ^a   Zhang, Yi ^b   Xian, Junming ^a   Zhao, Houyu ^a   Liu, Shixi ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Antisense oligonucleotide; Ataxia telangiectasia mutated (ATM); Head and neck squamous cell carcinoma; Nanoparticle; Radiosensitivity

Indexed keywords

ANTISENSE OLIGONUCLEOTIDE; ATM PROTEIN; LIPOFECTIN; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL CULTURE; DRUG DELIVERY SYSTEM; EMULSION; GENE EXPRESSION; HEAD AND NECK CARCINOMA; IRRADIATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIOSENSITIZATION; SQUAMOUS CELL CARCINOMA;

ANIMALS; CARCINOMA, SQUAMOUS CELL; CELL CYCLE PROTEINS; CELL LINE, TUMOR; CELL SURVIVAL; DNA-BINDING PROTEINS; ENDOCYTOSIS; FEMALE; GENE EXPRESSION; HEAD AND NECK NEOPLASMS; HUMANS; MICE; MICE, INBRED C3H; MUTAGENESIS; NANOPARTICLES; OLIGONUCLEOTIDES, ANTISENSE; PARTICLE SIZE; PROTEIN-SERINE-THREONINE KINASES; RADIATION TOLERANCE; RADIATION-SENSITIZING AGENTS; TUMOR SUPPRESSOR PROTEINS; X-RAYS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 67650784376     PISSN: 10849785     EISSN: None     Source Type: Journal    
DOI: 10.1089/cbr.2008.0557     Document Type: Article

References (28)

1. Cognetti DM, Weber RS, Lai SY. Head and neck cancer: An evolving treatment paradigm. Cancer 2008;113:1911.
2. Rhee JG, Li D, Suntharalingam M, et al. Radiosensitization of head/neck squamous cell carcinoma by adenovirusmediated expression of the nbs1 protein. Int J Radiat Oncol Biol Phys 2007;67:273.
3. O'Malley BW, Jr, Cope KA, Johnson CS, et al. A new immunocompetent murine model for oral cancer. Arch Oto-laryngol Head Neck Surg 1997;123:20.
4. Khurana D, Martin EA, Kasperbauer JL, et al. Characterization of a spontaneously arising murine squamous cell carcinoma (SCCVII) as a prerequisite for head and neck cancer immunotherapy. Head Neck 2001;23:899.
5. Lavin MF, Birrell G, Chen P, et al. atm signaling and genomic stability in response to DNA damage. Mutat Res 2005; 569:123.
6. Cariveau MJ, Tang X, Cui XL, et al. Characterization of an NBS1 c-terminal peptide that can inhibit ataxia-telangiectasiamutated (ATM)-mediated DNA damage responses and enhance radiosensitivity. Mol Pharmacol 2007;72:320.
7. Zou H, Zhao S, Zhang J, et al. Enhanced radiation-induced cytotoxic effect by 2-ME in glioma cells is mediated by induction of cell cycle arrest and DNA damage via activation of ATM pathways. Brain Res 2007;1185:231.
8. Goodarzi AA, Block WD, Lees-Miller SP. The role of ATM and ATR in DNA damage-induced cell cycle control. Prog Cell Cycle Res 2003;5:393.
9. Sarkaria JN, Eshleman JS. ATM as a target for novel radiosensitizers. Semin Radiat Oncol 2001;11:316.
10. Fan Z, Chakravarty P, Alfieri A, et al. Adenovirus-mediated antisense ATM gene transfer sensitizes prostate cancer cells to radiation. Cancer Gene Ther 2000;7:1307.
11. Guha C, Guha U, Tribius S, et al. Antisense ATM gene therapy: A strategy to increase the radiosensitivity of human tumors. Gene Ther 2000;7:852.
12. Fattal E, Bochot A. Ocular delivery of nucleic acids: Antisense oligonucleotides, aptamers, and sirna. Adv Drug Deliv Rev 2006;58:1203.
13. Kalota A, Dondeti VR, Gewirtz AM. Progress in the development of nucleic acid therapeutics. Handb Exp Pharmacol 2006:173.
14. Lecaroz C, Gamazo C, Blanco-Prieto MJ. Nanocarriers with gentamicin to treat intracellular pathogens. J Nanosci Na-notechnol 2006;6:3296.
15. Aukunuru JV, Sunkara G, Ayalasomayajula SP, et al. A biodegradable injectable implant sustains systemic and ocular delivery of an aldose reductase inhibitor and ameliorates biochemical changes in a galactose-fed rat model for diabetic complications. Pharm Res 2002;19:278.
16. De Rosa G, Quaglia F, La Rotonda MI, et al. Poly(lactide-coglycolide) microspheres for the controlled release of oligonucleotide/polyethylenimine complexes. J Pharm Sci 2002; 91:790.
17. Yin KJ, Chen SD, Lee JM, et al. ATM gene regulates oxygenglucose deprivation-induced nuclear factor-kappab DNA-binding activity and downstream apoptotic cascade in mouse cerebrovascular endothelial cells. Stroke 2002;33: 2471.
18. Aukunuru JV, Ayalasomayajula SP, Kompella UB. Nanoparticle formulation enhances the delivery and activity of a vascular endothelial growth factor antisense oligonucleotide in human retinal pigment epithelial cells. J Pharm Pharmacol 2003;55:1199.
19. Li Y, Zhou ZG, Xia QJ, et al. Toll-like receptor 4 detected in exocrine pancreas and the change of expression in ceruleininduced pancreatitis. Pancreas 2005;30:375.
20. Huang X, Wei Y, Li L, et al. Serum proteomics study of the squamous cell carcinoma antigen 1 in tongue cancer. Oral Oncol 2006;42:26.
21. Stephenson ML, Zamecnik PC. Inhibition of rous sarcoma viral RNA translation by a specific oligodeoxyribonucleotide. Proc Natl Acad Sci U S A 1978;75:285.
22. Jain R, Shah NH, Malick AW, et al. Controlled drug delivery by biodegradable poly(ester) devices: Different preparative approaches. Drug Dev Ind Pharm 1998;24:703.
23. Panyam J, Zhou WZ, Prabha S, et al. Rapid endo-lysosomal escape of poly(D, L-lactide-co-glycolide) nanoparticles: Implications for drug and gene delivery. FASEB J 2002;16: 1217.
24. Foster KA, Yazdanian M, Audus KL. Microparticulate uptake mechanisms of in-vitro cell culture models of the respiratory epithelium. J Pharm Pharmacol 2001;53:57.
25. De Rosa G, Maiuri MC, Ungaro F, et al. Enhanced intracellular uptake and inhibition of NF-kappa-b activation by decoy oligonucleotide released from PLGA microspheres. J Gene Med 2005;7:771.
26. Choi EK, Ji IM, Lee SR, et al. Radiosensitization of tumor cells by modulation of ATM kinase. Int J Radiat Biol 2006;82:277.
27. Reliene R, Schiestl RH. Antioxidant n-acetyl cysteine reduces incidence and multiplicity of lymphoma in atm deficient mice. DNA Repair (Amst) 2006;5:852.
28. Kim WJ, Vo QN, Shrivastav M, et al. Aberrant methylation of the ATM promoter correlates with increased radiosensitivity in a human colorectal tumor cell line. Oncogene 2002; 21:3864.