Drug titration patterns and HbA1c levels in type 2 diabetes

International Journal of Clinical Practice

Volumn 63, Issue 7, 2009, Pages 1008-1016

  Ross MacLean, J ^a   Chapman, R H ^b   Ferrufino, C P ^b   Krishnarajah, G ^a  

^a BRISTOL MYERS SQUIBB   (United States)

^b IQVIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALPHA GLUCOSIDASE INHIBITOR; GLUCOSE; HEMOGLOBIN A1C; INSULIN DERIVATIVE; METFORMIN; SULFONYLUREA; ANTIDIABETIC AGENT; GLUCOSE BLOOD LEVEL; GLYCOSYLATED HEMOGLOBIN;

ADULT; AGED; ARTICLE; CLINICAL EVALUATION; CONTROLLED STUDY; DEMOGRAPHY; DRUG DOSE TITRATION; DRUG USE; FEMALE; GLYCEMIC CONTROL; HEALTH CARE COST; HEALTH CARE UTILIZATION; HEMOGLOBIN BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICARE; MONOTHERAPY; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; NON INSULIN DEPENDENT DIABETES MELLITUS; PRESCRIPTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SOCIAL STATUS; ADOLESCENT; BLOOD; CLINICAL TRIAL; DIABETES MELLITUS, TYPE 2; DRUG MONITORING; GLUCOSE BLOOD LEVEL; METABOLISM; MIDDLE AGED; MULTICENTER STUDY; ORAL DRUG ADMINISTRATION; PROCEDURES; TREATMENT OUTCOME; YOUNG ADULT;

ADMINISTRATION, ORAL; ADOLESCENT; ADULT; AGED; BLOOD GLUCOSE; DIABETES MELLITUS, TYPE 2; DRUG MONITORING; FEMALE; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; HYPOGLYCEMIC AGENTS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; TREATMENT OUTCOME; YOUNG ADULT;

EID: 67650753962     PISSN: 13685031     EISSN: 17421241     Source Type: Journal    
DOI: 10.1111/j.1742-1241.2009.02094.x     Document Type: Article

References (26)

1. UK Prospective Diabetes Study (UKPDS) Group. UK Prospective Diabetes Study 16. Overview of 6 years' therapy of type II diabetes: a progressive disease. Diabetes 1995 44 : 1249 58.
2. Kahn SE. The relative contributions of insulin resistance and beta-cell dysfunction to the pathophysiology of type 2 diabetes. Diabetologia 2003 46 : 3 19. (Pubitemid 36237741)
3. Centers for Disease Control and Prevention. National Diabetes Fact Sheet: General Information and National Estimates on Diabetes in the United States, 2005. Atlanta, GA : Centers for Disease Control and Prevention, US Dept Health and Human Services, 2005. Available at: http://www.cdc.gov/diabetes/pubs/ factsheet05.htm.
4. Geiss LS, Wang J, Gregg EW. Long Term Trends in the Prevalence and Incidence of Diagnosed Diabetes [Abstract]. Presented at: American Diabetes Association 67th Annual Scientific Sessions; June 22-26 Chicago, IL, 2007. Abstract 125-0R.
5. Riddle MC. Glycemic management of type 2 diabetes: an emerging strategy with oral agents, insulins, and combinations. Endocrinol Metab Clin North Am 2005 34 : 77 98. (Pubitemid 40332504)
6. Karter AJ, Moffet HH, Liu J et al. Glycemic response to newly initiated diabetes therapies. Am J Manag Care 2007 13 : 598 606. (Pubitemid 350106949)
7. Brown JB, Nichols GA, Perry A. The burden of treatment failure in type 2 diabetes. Diabetes Care 2004 27 : 1535 40.
8. Parchman ML, Pugh JA, Romero RL, Bowers KW. Competing demands or clinical inertia: the case of elevated glycosylated hemoglobin. Ann Fam Med 2007 5 : 196 201. (Pubitemid 46889995)
9. Lawrence DB, Ragucci KR, Long LB, Parris BS, Helfer LA. Relationship of oral antihyperglycemic (sulfonylurea or metformin) medication adherence and hemoglobin A1c goal attainment for HMO patients enrolled in a diabetes disease management program. J Manag Care Pharm 2006 12 : 466 71.
10. Hertz RP, Unger AN, Lustik MB. Adherence with pharmacotherapy for type 2 diabetes: a retrospective cohort study of adults with employer-sponsored health insurance. Clin Ther 2005 27 : 1064 73.
11. Nathan DM, Buse JB, Davidson MB et al. Management of hyperglycemia in type 2 diabetes: a consensus algorithm for the initiation and adjustment of therapy: a consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes. Diabetes Care 2006 29 : 1963 72.
12. Jellinger PS, Davidson JA, Blonde L et al. Road maps to achieve glycemic control in type 2 diabetes mellitus: ACE/AACE Diabetes Road Map Task Force. Endocr Pract 2007 13 : 260 8.
13. Nichols GA, Koo YH, Shah SN. Delay of insulin addition to oral combination therapy despite inadequate glycemic control: delay of insulin therapy. J Gen Intern Med 2007 22 : 453 8.
14. Nichols GA, Glauber HS, Javor K, Brown JB. Achieving further glycemic control in type 2 diabetes mellitus. West J Med 2000 173 : 175 9.
15. Rodbard HW, Blonde L, Braithwaite SS et al. American Association of Clinical Endocrinologists medical guidelines for clinical practice for the management of diabetes mellitus. Endocr Pract 2007 13 (Suppl. 1 1 68.
16. American Diabetes Association. Standards of medical care in diabetes - 2008. Diabetes Care 2008 31 (Suppl. 1 S12 54.
17. Saydah SH, Fradkin J, Cowie CC. Poor control of risk factors for vascular disease among adults with previously diagnosed diabetes. JAMA 2004 291 : 335 42.
18. US Centers for Disease Control and Prevention. Data & Trends. Age-Adjusted Rates of A1c per 100 Adults With Diabetes. United States : US Department of Health and Human Services, 2000-2005. Available at: http://www.cdc.gov/diabetes/statistics/preventive/fY-ac1test.htm.
19. Coberley CR, McGinnis M, Orr PM et al. Association between frequency of telephonic contact and clinical testing for a large, geographically diverse diabetes disease management population. Dis Manag 2007 10 : 101 9.
20. Thomas KG, Thomas MR, Stroebel RJ et al. Use of a registry-generated audit, feedback, and patient reminder intervention in an internal medicine resident clinic-a randomized trial. J Gen Intern Med 2007 22 : 1740 4.
21. Nau DP. Evaluating medication use for continuous quality improvement in diabetes care. J Manag Care Pharm 2002 8 : 378 82.
22. American College of Endocrinology/American Association of Clinical Endocrinologists. American College of Endocrinology Consensus Statement on Guidelines for Glycemic Control. Endocr Pract 2002 8 : 5 11.
23. American Diabetes Association. Standards of medical care for patients with diabetes mellitus. Diabetes Care 2002 25 : 213 29.
24. Riedel AA, Heien H, Wogen J, Plauschinat CA. Loss of glycemic control in patients with type 2 diabetes mellitus who were receiving initial metformin, sulfonylurea, or thiazolidinedione monotherapy. Pharmacotherapy 2007 27 : 1102 10.
25. Riddle MC. Oral pharmacologic management of type 2 diabetes. Am Fam Physician 1999 60 : 2613 20.
26. Sheehan MT. Current therapeutic options in type 2 diabetes mellitus: a practical approach. Clin Med Res 2003 1 : 189 200.