First indications demonstrating the preventive effects of NZ-419, a novel intrinsic antioxidant, on the initiation and/or progression of chronic renal failure in rats

Biological and Pharmaceutical Bulletin

Volumn 32, Issue 7, 2009, Pages 1204-1208

  Ienaga, Kazuharu ^a   Mikami, Hiroki ^a   Yokozawa, Takako ^b  

^a Nippon Zoki Pharmaceutical Co Ltd   (Japan)

^b UNIVERSITY OF TOYAMA   (Japan)

Author keywords

Chronic renal failure; Methylguanidine; NZ 419; Oxidative stress

Indexed keywords

5 HYDROXY 1 METHYLIMIDAZOLIDINE 2 4 DIONE; ADENINE; ANTIOXIDANT; CALCIUM; CREATININE; GUANIDINOSUCCINIC ACID; METHYLGUANIDINE; NZ 419; PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CALCIUM BLOOD LEVEL; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CREATININE CLEARANCE; CREATININE URINE LEVEL; DISEASE COURSE; DOSE RESPONSE; DRUG EFFECT; DRUG MEGADOSE; DRUG STRUCTURE; KIDNEY FUNCTION; LIVER LEVEL; MALE; MUSCLE LEVEL; NONHUMAN; OXIDATIVE STRESS; PHOSPHATE BLOOD LEVEL; RAT; UREA NITROGEN BLOOD LEVEL; UREMIA;

ANIMALS; ANTIOXIDANTS; BIOLOGICAL MARKERS; CREATININE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANIDINES; HYDANTOINS; KIDNEY FAILURE, CHRONIC; KIDNEY FUNCTION TESTS; MALE; METHYLGUANIDINE; OXIDATIVE STRESS; RATS; RATS, WISTAR; SUCCINATES;

EID: 67650747672     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.32.1204     Document Type: Article

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