Inhibition of arginine synthesis by urea: A mechanism for arginine deficiency in renal failure which leads to increased hydroxyl radical generation

Molecular and Cellular Biochemistry

Volumn 244, Issue 1-2, 2003, Pages 11-15

  Aoyagi, Kazumasa ^a  

^a TSUKUBA UNIVERSITY OF TECHNOLOGY   (Japan)

Author keywords

Arginine; Guanidinosuccinic acid; Reactive oxygen; Urea; Uremia

Indexed keywords

AMMONIUM CHLORIDE; ARGININE; ARGININOSUCCINIC ACID; BICARBONATE; BOVINE SERUM ALBUMIN; CITRULLINE; GUANIDINOSUCCINIC ACID; HYDROXYL RADICAL; LACTATE SODIUM; NITRIC OXIDE; ORNITHINE; SODIUM CHLORIDE; SUPEROXIDE; UREA;

AMINO ACID ANALYSIS; AMINO ACID BLOOD LEVEL; AMINO ACID SYNTHESIS; ANIMAL CELL; AUTOANALYZER; BLOOD SAMPLING; BODY WEIGHT; CELL ISOLATION; CONTROLLED STUDY; CRYOPRESERVATION; ENZYME DEFICIENCY; HISTOPATHOLOGY; IN VIVO STUDY; INCUBATION TIME; KIDNEY FAILURE; KIDNEY PARENCHYMA; LIVER; LIVER CELL; MALE; NONHUMAN; OXIDATIVE STRESS; RAT; REGULATORY MECHANISM; REVIEW; STATISTICAL SIGNIFICANCE; UREA CYCLE;

ANIMALS; ARGININE; CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANIDINES; HEPATOCYTES; HYDROXYL RADICAL; KIDNEY FAILURE; MALE; MODELS, BIOLOGICAL; MOLSIDOMINE; NITRIC OXIDE; NITRIC OXIDE DONORS; ORNITHINE; OXYGEN; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUCCINATES; UREA;

ANIMALIA; BOVINAE; RATTUS NORVEGICUS;

EID: 0037307003     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1022479017087     Document Type: Review

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