A small-molecule inhibitor of nipah virus envelope protein-mediated membrane fusion

Journal of Medicinal Chemistry

Volumn 52, Issue 14, 2009, Pages 4257-4265

  Niedermeier, Sabine ^a   Singethan, Katrin ^a   Rohrer, Sebastian G ^b   Matz, Magnus ^b   Kossner, Markus ^b   Diederich, Sandra ^c   Maisner, Andrea ^c   Schmitz, Jens ^a   Hiltensperger, Georg ^a   Baumann, Knut ^b   Holzgrabe, Ulrike ^a   Schneider Schaulies, Jurgen ^a  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b TECHNICAL UNIVERSITY OF BRAUNSCHWEIG   (Germany)

^c PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

7 (4 CARBAMOYLPIPERIDIN 1 YL) 1 CYCLOPROPYL N (2,4 DICHLOROBENZYL) 6 FLUORO 4 OXO 1,4 DIHYDROQUINOLINE 3 CARBOXAMIDE; ANTIVIRUS AGENT; ETHYL 1 [3 (2,4 DICHLOROBENZYLCARBAMOYL) 1 ETHYL 6 FLUORO 4 OXO 1,4 DIHYDROQUINOLIN 7 YL]PIPERIDINE 4 CARBOXYLATE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS FUSION PROTEIN;

ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; CELL FUSION; CONTROLLED STUDY; DISEASE SEVERITY; DRUG CYTOTOXICITY; DRUG DESIGN; DRUG SCREENING; MEASLES VIRUS; MEMBRANE FUSION; MOLECULAR MODEL; MORTALITY; NIPAH VIRUS; NONHUMAN; PARAMYXOVIRUS; STRUCTURE ACTIVITY RELATION; SWINE; VERO CELL; VIRUS ENCEPHALITIS;

ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COMPUTER SIMULATION; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MEASLES VIRUS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NIPAH VIRUS; QUINOLONES; VIRAL ENVELOPE PROTEINS; VIRUS INTERNALIZATION;

EID: 67650723141     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm900411s     Document Type: Article

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