Voltage-dependent calcium signaling in rat cerebellar unipolar brush cells

Neuroscience

Volumn 162, Issue 3, 2009, Pages 702-712

  Birnstiel, S ^a   Slater, N T ^a   McCrimmon, D R ^a   Mugnaini, E ^a   Hartell, N A ^b  

^a NORTHWESTERN UNIVERSITY   (United States)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

Author keywords

calcium; cerebellum; L type calcium channels; T type calcium channels; unipolar brush cell

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM CHANNEL T TYPE; CALCIUM ION; GLUTAMIC ACID; VOLTAGE GATED CALCIUM CHANNEL;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRUSH BORDER; CALCIUM CELL LEVEL; CALCIUM CURRENT; CALCIUM SIGNALING; CELL POPULATION; CEREBELLUM; CHANNEL GATING; CONTROLLED STUDY; DENDRITE; GRANULE CELL; INTERNEURON; MALE; MOSSY FIBER; NERVE CELL NETWORK; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; SYNAPSE;

ACTION POTENTIALS; ANIMALS; ANIMALS, NEWBORN; BIOPHYSICS; CALCIUM; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; CALCIUM SIGNALING; CEREBELLUM; ELECTRIC STIMULATION; MALE; NEURONS; PATCH-CLAMP TECHNIQUES; RATS; RATS, SPRAGUE-DAWLEY; RATS, WISTAR; SODIUM CHANNEL BLOCKERS; TETRODOTOXIN;

EID: 67650704918     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2009.01.051     Document Type: Article

References (51)

1. Afshari F.S., Ptak K., Khaliq Z.M., Grieco T.M., Slater N.T., McCrimmon D.R., and Raman I.M. Resurgent Na currents in four classes of neurons of the cerebellum. J Neurophysiol 92 (2004) 2831-2843
2. Bean B.P. Classes of calcium channels in vertebrate cells. Annu Rev Physiol 51 (1989) 367-384
3. Billups D., Liu Y.B., Birnstiel S., and Slater N.T. NMDA receptor-mediated currents in rat cerebellar granule and unipolar brush cells. J Neurophysiol 87 (2002) 1948-1959
4. Birnstiel S., Slater N.T., McCrimmon D.R., Mugnaini E., and Hartell N.A. Voltage-dependent calcium signalling in cerebellar unipolar brush cells. Br Neurosci Assoc Abstr 18 (2005) P13.01
5. Birnstiel S., Slater N.T., Mugnaini E., and Hartell N.A. Calcium signaling in rat cerebellar unipolar brush cells, UBCs. Soc Neurosci Abstr 258 (2003) 14
6. 2+ conductance. Synapse 1 (1987) 582-588
7. Chadderton P., Margrie T.W., and Häusser M. Integration of quanta in cerebellar granule cells during sensory processing. Nature 428 (2004) 856-860
8. 2+ influx. J Neurophysiol 73 (1995) 2553-2557
9. Crill W.E. Persistent sodium current in mammalian central neurons. Annu Rev Physiol 58 (1996) 349-362
10. Crunelli V., Toth T.I., Cope D.W., Blethyn K., and Hughes S.W. The "window" T-type calcium current in brain dynamics of different behavioural states. J Physiol 562 (2005) 121-129
11. 2+ action potentials in immature rat cerebellar granule cells in situ. J Neurophysiol 78 (1997) 1631-1642
12. Destexhe A., Neubig M., Ulrich D., and Huguenard J. Dendritic low-threshold calcium currents in thalamic relay cells. J Neurosci 18 (1998) 3574-3588
13. 2+ conductances define and encode the bimodal firing pattern of vestibulocerebellar unipolar brush cells. J Neurosci 27 (2007) 3823-3838
14. Dugue G.P., Dumoulin A., Triller A., and Dieudonne S. Target-dependent use of coreleased inhibitory transmitters at central synapses. J Neurosci 25 (2005) 6490-6498
15. Gerber U., Greene R.W., and McCarley R.W. Repetitive firing properties of medial pontine reticular formation neurones of the rat recorded in vitro. J Physiol (Lond) 410 (1989) 533-560
16. Greene R.W., Haas H.L., and McCarley R.W. A low threshold calcium spike mediates firing pattern alterations in pontine reticular neurons. Science 234 (1986) 738-740
17. Huguenard J.R. Low-threshold calcium currents in central nervous system neurons. Annu Rev Physiol 58 (1996) 329-348
18. Huguenard J.R., and Prince D.A. A novel T-type current underlies prolonged Ca(2+)-dependent burst firing in GABAergic neurons of rat thalamic reticular nucleus. J Neurosci 12 (1992) 3804-3817
19. Jaarsma D., Diño M.R., Ohishi H., Shigemoto R., and Mugnaini E. Metabotropic glutamate receptors are associated with nonsynaptic appendages of unipolar brush cells in rat cerebellar cortex and cochlear nuclear complex. J Neurocytol 27 (1998) 303-327
20. Jahnsen H., and Llinás R. Ionic basis for the elector-responsiveness and oscillatory properties of guinea-pig thalamic neurones in vitro. J Physiol (Lond) 349 (1984) 227-247
21. Jakab R.L., and Hamori J. Quantitative morphology and synaptology of cerebellar glomeruli in the rat. Anat Embryol (Berl) 179 (1988) 81-88
22. Karst H., Joëls M., and Wadman W.J. Low-threshold calcium current in dendrites of the adult rat hippocampus. Neurosci Lett 164 (1993) 154-158
23. Kinney G.A., Overstreet L.S., and Slater N.T. Prolonged physiological entrapment of glutamate in the synaptic cleft of cerebellar unipolar brush cells. J Neurophysiol 78 (1997) 1320-1333
24. Llinás R., and Yarom Y. Electrophysiology of mammalian inferior olivary neurones in vitro. Different types of voltage-dependent ionic conductances. J Physiol (Lond) 315 (1981) 549-567
25. Llinás R., and Yarom Y. Properties and distribution of ionic conductances generating electroresponsiveness of mammalian inferior olivary neurones in vitro. J Physiol (Lond) 315 (1981) 569-584
26. Magee J.C., and Johnston D. Synaptic activation of voltage-gated channels in the dendrites of hippocampal pyramidal neurons. Science 268 (1995) 301-304
27. Markram H., Helm P.J., and Sakmann B. Dendritic calcium transients evoked by single back-propagating action potentials in rat neocortical pyramidal neurons. J Physiol (Lond) 485 (1995) 1-20
28. Markram H., and Sakmann B. Calcium transients in dendrites of neocortical neurons evoked by single subthreshold excitatory postsynaptic potentials via low-voltage-activated calcium channels. Proc Natl Acad Sci U S A 91 (1994) 5207-5211
29. McCormick D.A. Cortical and subcortical generators of normal and abnormal rhythmicity. Int Rev Neurobiol 49 (2002) 99-114
30. McDonough S.I., and Bean B.P. Mibefradil inhibition of T-type calcium channels in cerebellar Purkinje neurons. Mol Pharmacol 54 (1998) 1080-1087
31. Molineux M.L., McRory J.E., McKay B.E., Hamid J., Mehaffey W.H., Rehak R., Snutch T.P., Zamponi G.W., and Turner R.W. Specific T-type calcium channel isoforms are associated with distinct burst phenotypes in deep cerebellar nuclear neurons. Proc Natl Acad Sci U S A 103 (2006) 5555-5560
32. Morin F., Diño M.R., and Mugnaini E. Postnatal differentiation of unipolar brush cells and mossy fiber-unipolar brush cell synapses in rat cerebellum. Neuroscience 104 (2001) 1127-1139
33. Mossadeghi B., and Slater N.T. Persistent and resurgent sodium currents in cerebellar unipolar brush cells. Soc Neurosci Abstr 24 (1998) 1078
34. Nunzi M.G., Birnstiel S., Bhattacharyya B.J., Slater N.T., and Mugnaini E. Unipolar brush cells form a glutamatergic projection system within the mouse cerebellar cortex. J Comp Neurol 434 (2001) 329-341
35. Nunzi M.G., Russo M., and Mugnaini E. Vesicular glutamate transporters VGLUT1 and VGLUT2 define two subsets of unipolar brush cells in organotypic cultures of mouse vestibulocerebellum. Neuroscience 122 (2003) 359-371
36. Nunzi M.G., Shigemoto R., and Mugnaini E. Differential expression of calretinin and metabotropic glutamate receptor mGluR1alpha defines subsets of unipolar brush cells in mouse cerebellum. J Comp Neurol 451 (2002) 189-199
37. Pape H.C. Queer current and pacemaker: the hyperpolarization-activated cation current in neurons. Annu Rev Physiol 58 (1996) 299-327
38. Perez-Reyes E. Molecular physiology of low-voltage-activated T-type calcium channels. Physiol Rev 83 (2003) 117-161
39. Prince D.A., and Connors B.W. Mechanisms of interictal epileptogenesis. Adv Neurol 44 (1986) 275-299
40. Raman I.M., and Bean B.P. Resurgent sodium current and action potential formation in dissociated cerebellar Purkinje neurons. J Neurosci 17 (1997) 4517-4526
41. Raman I.M., Sprunger L.K., Meisler M.H., and Bean B.P. Altered subthreshold sodium currents and disrupted firing patterns in Purkinje neurons of Scn8a mutant mice. Neuron 19 (1997) 881-891
42. Rossi D.J., Alford S., Mugnaini E., and Slater N.T. Properties of transmission at a giant glutamatergic synapse in cerebellum: the mossy-fiber-unipolar brush cell synapse. J Neurophysiol 74 (1995) 24-42
43. Russo M.J., Mugnaini E., and Martina M. Intrinsic properties and mechanisms of spontaneous firing in mouse cerebellar unipolar brush cells. J Physiol 581 (2007) 709-724
44. Russo M.J., Yau H.J., Nunzi M.G., Mugnaini E., and Martina M. Dynamic metabotropic control of intrinsic firing in cerebellar unipolar brush cells. J Neurophysiol 100 (2008) 3351-3360
45. Simpson J.I., Hulscher H.C., Sabel-Goedknegt E., and Ruigrok T.J. Between in and out: linking morphology and physiology of cerebellar cortical interneurons. Prog Brain Res 148 (2005) 329-340
46. Sims R.E., and Hartell N.A. Differential susceptibility to synaptic plasticity reveals a functional specialization of ascending axon and parallel fiber synapses to cerebellar Purkinje cells. J Neurosci 26 (2006) 5153-5159
47. Sims R.E., and Hartell N.A. Differences in transmission properties and susceptibility to long-term depression reveal functional specialization of ascending axon and parallel fiber synapses to Purkinje cells. J Neurosci 25 (2005) 3246-3257
48. Slater N.T., Rossi D.J., and Kinney G.A. Physiology of transmission at a giant glutamatergic synapse in cerebellum. Prog Brain Res 114 (1997) 151-163
49. Steriade M. Impact of network activities on neuronal properties in corticothalamic systems. J Neurophysiol 86 (2001) 1-39
50. Stevens D.R., and Haas H.L. Calcium-dependent prepotentials contribute to spontaneous activity in rat tuberomammillary neurons. J Physiol (Lond) 493 (1996) 747-754
51. 2+-dependent slow afterhyperpolarization in hippocampal neurones: effects of internally applied anions. Pflugers Arch 426 (1994) 247-253