Feasibility of infectious prion digestion using mild conditions and commercial subtilisin

Journal of Virological Methods

Volumn 161, Issue 1, 2009, Pages 168-172

  Pilon, John L ^a,d   Nash, Paul B ^a   Arver, Terry ^b   Hoglund, Don ^c   VerCauteren, Kurt C ^a  

^a NATIONAL WILDLIFE RESEARCH CENTER   (United States)

^b Prion Tech   (United States)

^c Prion Tech   (United States)

^d TOLMAR Inc   (United States)

Author keywords

Chronic wasting disease; Decontamination; Mouse adapted scrapie; Prion; Subtilisin

Indexed keywords

HYPOCHLORITE; PRION PROTEIN; SUBTILISIN;

ALKALINITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTOCLAVE; BIOASSAY; BRAIN HOMOGENATE; CONTROLLED STUDY; ENZYME ACTIVITY; FEASIBILITY STUDY; HIGH TEMPERATURE PROCEDURES; MOUSE; NONHUMAN; PH; PRION; PRIORITY JOURNAL; PROTEIN DEGRADATION; SCRAPIE; VIRUS INFECTION; VIRUS VIRULENCE;

ANIMALS; DECONTAMINATION; DISINFECTANTS; DISINFECTION; HYDROGEN-ION CONCENTRATION; HYPOCHLOROUS ACID; MICE; MICE, INBRED C57BL; PRIONS; STERILIZATION; SUBTILISIN;

MUS;

EID: 67650655609     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jviromet.2009.04.040     Document Type: Article

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