Extracorporeal shock wave-mediated changes in proliferation, differentiation, and gene expression of human osteoblasts

Journal of Trauma - Injury, Infection and Critical Care

Volumn 65, Issue 6, 2008, Pages 1402-1410

  Hofmann, Alexander ^a   Ritz, Ulrike ^a   Hessmann, Martin Henri ^a   Alini, Mauro ^b   Rommens, Pol Maria ^a   Rompe, Jan Dirk ^c  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b AO RESEARCH INSTITUTE   (Switzerland)

^c OrthoTrauma Clinic   (Germany)

Author keywords

Extracorporeal shock wave therapy; High density microarray; Osteoblast

Indexed keywords

ALKALINE PHOSPHATASE; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 2 INDUCIBLE KINASE; CALBINDIN; CARTILAGE OLIGOMERIC MATRIX PROTEIN; CHORDIN; COLLAGEN TYPE 2 ALPHA1; COLLAGEN TYPE 6 ALPHA1; CXCL2 CHEMOKINE; FORKHEAD BOX PROTEIN M1; G PROTEIN COUPLED RECEPTOR; G PROTEIN COUPLED RECEPTOR C5B; GLUTAMYL AMINOPEPTIDASE; INTERLEUKIN 1BETA CONVERTING ENZYME; MATRILIN 3; PARATHYROID HORMONE RELATED PROTEIN; PROLACTIN; PROSTAGLANDIN E RECEPTOR; PROSTAGLANDIN E RECEPTOR 3; PROTEIN; PROTEIN CYLD; PROTEIN F2RL1; PROTEIN FOXM1; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE 2; PROTEIN INTERACTING WITH PROTEIN KINASE C; PROTEIN MSR1; PROTEIN OR1E2; PROTEIN TGIF2; RGS2 PROTEIN; SOMATOSTATIN RECEPTOR 2; UNCLASSIFIED DRUG;

ARTICLE; BONE DEVELOPMENT; BONE MINERALIZATION; CANCELLOUS BONE; CELL DIFFERENTIATION; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DENSITY; ENERGY; GENE EXPRESSION; GENE EXPRESSION PROFILING; HOMEOSTASIS; HUMAN; HUMAN CELL; MICROARRAY ANALYSIS; NORMAL HUMAN; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; SHOCK WAVE; UPREGULATION; BONE DENSITY; CELL DIVISION; CYTOLOGY; DNA MICROARRAY; GENETICS; IN VITRO STUDY; METABOLISM; PHYSIOLOGY; RADIATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ALKALINE PHOSPHATASE; BONE DENSITY; CELL DIFFERENTIATION; CELL DIVISION; GENE EXPRESSION; GENE EXPRESSION PROFILING; HIGH-ENERGY SHOCK WAVES; HUMANS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOBLASTS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 67650627165     PISSN: 00225282     EISSN: 15298809     Source Type: Journal    
DOI: 10.1097/TA.0b013e318173e7c2     Document Type: Article

References (67)

1. Rompe JD, Rosendahl T, Schollner C, Theis C. High-energy extracorporeal shock wave treatment of nonunions. Clin Orthop Relat Res. 2001; 387: 102-111.
2. Shrivastava SK, Kailash. Shock wave treatment in medicine. J Biosci. 2005; 30: 269-275.
3. Ikeda K, Tomita K, Takayama K. Application of extracorporeal shock wave on bone: preliminary report. J Trauma. 1999; 47: 946-950.
4. Martini L, Giavaresi G, Fini M, Borsari V, Torricelli P, Giardino R. Early effects of extracorporeal shock wave treatment on osteoblastlike cells: a comparative study between electromagnetic and electrohydraulic devices. J Trauma. 2006; 61: 1198-1206.
5. Chen YJ, Kuo YR, Yang KD, Wang CJ, Huang HC, Wang FS. Shock wave application enhances pertussis toxin protein-sensitive bone formation of segmental femoral defect in rats. J Bone Miner Res. 2003; 18: 2169-2179.
6. Delius M, Draenert K, Al Diek Y, Draenert Y. Biological effects of shock waves: in vivo effect of high energy pulses on rabbit bone. Ultrasound Med Biol. 1995; 21: 1219-1225.
7. Haupt G, Haupt A, Ekkernkamp A, Gerety B, Chvapil M. Influence of shock waves on fracture healing. Urology. 1992; 39: 529-532.
8. Wang FS, Yang KD, Chen RF, Wang CJ, Sheen-Chen SM. Extracorporeal shock wave promotes growth and differentiation of bone-marrow stromal cells towards osteoprogenitors associated with induction of TGF-beta1. J Bone Joint Surg Br. 2002; 84: 457-461.
9. Martini L, Fini M, Giavaresi G, et al. Primary osteoblasts response to shock wave therapy using different parameters. Artif Cells Blood Substit Immobil Biotechnol. 2003; 31: 449-466.
10. Tam KF, Cheung WH, Lee KM, Qin L, Leung KS. Delayed stimulatory effect of low-intensity shockwaves on human periosteal cells. Clin Orthop Relat Res. 2005; 438: 260-265.
11. Biedermann R, Martin A, Handle G, Auckenthaler T, Bach C, Krismer M. Extracorporeal shock waves in the treatment of nonunions. J Trauma. 2003; 54: 936-942.
12. Bara T, Synder M. Nine-years experience with the use of shock waves for treatment of bone union disturbances. Ortop Traumatol Rehabil. 2007; 9: 254-258.
13. Rompe JD, Eysel P, Hopf C, Vogel J, Kullmer K. Extracorporeal shockwave treatment of delayed bone healing. A critical assessment. Unfallchirurg. 1997; 100: 845-849.
14. Schaden W, Fischer A, Sailler A. Extracorporeal shock wave therapy of nonunion or delayed osseous union. Clin Orthop Relat Res. 2001; 387: 90-94.
15. Vogel J, Hopf C, Eysel P, Rompe JD. Application of extracorporeal shockwaves in the treatment of pseudarthrosis of the lower extremity. Preliminary results. Arch Orthop Trauma Surg. 1997; 116: 480-483.
16. Schleberger R, Senge T. Non-invasive treatment of long-bone pseudarthrosis by shock waves (ESWL). Arch Orthop Trauma Surg. 1992; 111: 224-227.
17. Hofmann A, Konrad L, Gotzen L, Printz H, Ramaswamy A, Hofmann C. Bioengineered human bone tissue using autogenous osteoblasts cultured on different biomatrices. J Biomed Mater Res A. 2003; 67: 191-199.
18. Hofmann A, Konrad L, Hessmann MH, et al. The influence of bone allograft processing on osteoblast attachment and function. J Orthop Res. 2005; 23: 846-854.
19. Laurencin CT, Attawia MA, Elgendy HE, Herbert KM. Tissue engineered bone-regeneration using degradable polymers: the formation of mineralized matrices. Bone. 1996; 19: 93-99.
20. Kaulesar Johannes EJ, Sukul DM, Bijma AM, Mulder PG. Effects of high-energy shockwaves on normal human fibroblasts in suspension. J Surg Res. 1994; 57: 677-681.
21. Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods. 1983; 65: 55-63.
22. Kendziorski C, Irizarry RA, Chen KS, Haag JD, Gould MN. On the utility of pooling biological samples in microarray experiments. Proc Natl Acad Sci U S A. 2005; 102: 4252-4257.
23. Kendziorski CM, Zhang Y, Lan H, Attie AD. The efficiency of pooling mRNA in microarray experiments. Biostatistics. 2003; 4: 465-477.
24. Horwitz MJ, Tedesco MB, Gundberg C, Garcia-Ocana A, Stewart AF. Short-term, high-dose parathyroid hormone-related protein as a skeletal anabolic agent for the treatment of postmenopausal osteoporosis. J Clin Endocrinol Metab. 2003; 88: 569-575.
25. Mori S, Jee WS, Li XJ. Production of new trabecular bone in osteopenic ovariectomized rats by prostaglandin E2. Calcif Tissue Int. 1992; 50: 80-87.
26. Raisz LG, Kream BE. Regulation of bone formation. N Engl J Med. 1983; 309: 29-35.
27. Stewart AF, Cain RL, Burr DB, Jacob D, Turner CH, Hock JM. Sixmonth daily administration of parathyroid hormone and parathyroid hormone-related protein peptides to adult ovariectomized rats markedly enhances bone mass and biomechanical properties: a comparison of human parathyroid hormone 1-34, parathyroid hormone-related protein 1-36, and SDZ-parathyroid hormone 893. J Bone Miner Res. 2000; 15: 1517-1525.
28. Frank O, Heim M, Jakob M, et al. Real-time quantitative RT-PCR analysis of human bone marrow stromal cells during osteogenic differentiation in vitro. J Cell Biochem. 2002; 85: 737-746.
29. Meury T, Verrier S, Alini M. Human endothelial cells inhibit BMSC differentiation into mature osteoblasts in vitro by interfering with osterix expression. J Cell Biochem. 2006; 98: 992-1006.
30. Dangelo M, Sarment DP, Billings PC, Pacifici M. Activation of transforming growth factor beta in chondrocytes undergoing endochondral ossification. J Bone Miner Res. 2001; 16: 2339-2347.
31. Wang FS, Wang CJ, Sheen-Chen SM, Kuo YR, Chen RF, Yang KD. Superoxide mediates shock wave induction of ERK-dependent osteogenic transcription factor (CBFA1) and mesenchymal cell differentiation toward osteoprogenitors. J Biol Chem. 2002; 277: 10931-10937.
32. Martini L, Giavaresi G, Fini M, et al. Effect of extracorporeal shock wave therapy on osteoblast like cells. Clin Orthop Relat Res. 2003; 413: 269-280.
33. Torricelli P, Fini M, Giavaresi G, et al. Comparative interspecies investigation on osteoblast cultures: data on cell viability and synthetic activity. Biomed Pharmacother. 2003; 57: 57-62.
34. Bilbe G, Roberts E, Birch M, Evans DB. PCR phenotyping of cytokines, growth factors and their receptors and bone matrix proteins in human osteoblast-like cell lines. Bone. 1996; 19: 437-445.
35. Ramires PA, Cosentino F, Milella E, Torricelli P, Giavaresi G, Giardino R. In vitro response of primary rat osteoblasts to titania/ hydroxyapatite coatings compared with transformed human osteoblast-like cells. J Mater Sci Mater Med. 2002; 13: 797-801.
36. Shur I, Lokiec F, Bleiberg I, Benayahu D. Differential gene expression of cultured human osteoblasts. J Cell Biochem. 2001; 83: 547-553.
37. Birch MA, Skerry TM. Differential regulation of syndecan expression by osteosarcoma cell lines in response to cytokines but not osteotropic hormones. Bone. 1999; 24: 571-578.
38. Okazaki R, Conover CA, Harris SA, Spelsberg TC, Riggs BL. Normal human osteoblast-like cells consistently express genes for insulin-like growth factors I and II but transformed human osteoblast cell lines do not. J Bone Miner Res. 1995; 10: 788-795.
39. Samadfam R, Gallant MA, Miousse MC, Parent JL, de Brum-Fernandes AJ. Implication of prostaglandin receptors in the accumulation of osteoprotegerin in human osteoblast cultures. J Rheumatol. 2006; 33: 1167-1175.
40. Siddiqi A, Parsons MP, Lewis JL, Monson JP, Williams GR, Burrin JM. TR expression and function in human bone marrow stromal and osteoblast-like cells. J Clin Endocrinol Metab. 2002; 87: 906-914.
41. Annes JP, Chen Y, Munger JS, Rifkin DB. Integrin alphaVbeta6-mediated activation of latent TGF-beta requires the latent TGF-beta binding protein-1. J Cell Biol. 2004; 165: 723-734.
42. de Gortazar AR, Alonso V, Alvarez-Arroyo MV, Esbrit P. Transient exposure to PTHrP (107-139) exerts anabolic effects through vascular endothelial growth factor receptor 2 in human osteoblastic cells in vitro. Calcif Tissue Int. 2006; 79: 360-369.
43. Strewler GJ. The physiology of parathyroid hormone-related protein. N Engl J Med. 2000; 342: 177-185.
44. Namba T, Sugimoto Y, Negishi M, et al. Alternative splicing of Cterminal tail of prostaglandin E receptor subtype EP3 determines G-protein specificity. Nature. 1993; 365: 166-170.
45. Bodine PV, Komm BS. Wnt signaling and osteoblastogenesis. Rev Endocr Metab Disord. 2006; 7: 33-39.
46. Bowler WB, Gallagher JA, Bilbe G. G-protein coupled receptors in bone. Front Biosci. 1998; 3: 769-780.
47. Mackie EJ, Trechsel U, Bruns C. Somatostatin receptors are restricted to a subpopulation of osteoblast-like cells during endochondral bone formation. Development. 1990; 110: 1233-1239.
48. Di Cesare PE, Fang C, Leslie MP, Tulli H, Perris R, Carlson CS. Expression of cartilage oligomeric matrix protein (COMP) by embryonic and adult osteoblasts. J Orthop Res. 2000; 18: 713-720.
49. Ballock RT, O'Keefe RJ. The biology of the growth plate. J Bone Joint Surg Am. 2003; 85: 715-726.
50. Ko Y, Kobbe B, Nicolae C, et al. Matrilin-3 is dispensable for mouse skeletal growth and development. Mol Cell Biol. 2004; 24: 1691-1699.
51. Petryk A, Shimmi O, Jia X, et al. Twisted gastrulation and chordin inhibit differentiation and mineralization in MC3T3-E1 osteoblastlike cells. Bone. 2005; 36: 617-626.
52. Kearns AE, Donohue MM, Sanyal B, Demay MB. Cloning and characterization of a novel protein kinase that impairs osteoblast differentiation in vitro. J Biol Chem. 2001; 276: 42213-42218.
53. Ritz U, Rompe JD, Ackermann A, Heine J, Rommens PM, Hofmann A. Gene Array analysis of shock wave induced changes of gene expression in human osteoblast cultures from patients with fracture non-unions. Bone. 2005; 36: S269.
54. Churchill GA. Fundamentals of experimental design for cDNA microarrays. Nat Genet. 2002; 32: 490-495.
55. Dobbin K, Simon R. Sample size determination in microarray experiments for class comparison and prognostic classification. Biostatistics. 2005; 6: 27-38.
56. Han ES, Wu YM, McCarter R, Nelson JF, Richardson A, Hilsenbeck SG. Reproducibility, sources of variability, pooling, and sample size: important considerations for the design of high-density oligonucleotide array experiments. J Gerontol A Biol Sci Med Sci. 2004; 59: 306-315.
57. Caetano AR, Johnson RY, Ford JJ, Pomp D. Microarray profiling for differential gene expression in ovaries and ovarian follicles of pigs selected for increased ovulation rate. Genetics. 2004; 168: 1529-1537.
58. Jin W, Riley RM, Wolfinger RD, White KP, Passador-Gurgel G, Gibson G. The contributions of sex, genotype and age to transcriptional variance in Drosophila melanogaster. Nat Genet. 2001; 29: 389-395.
59. Kerr MK. Experimental design to make the most of microarray studies. Methods Mol Biol. 2003; 224: 137-147: 137-147.
60. Chuaqui RF, Bonner RF, Best CJ, et al. Post-analysis follow-up and validation of microarray experiments. Nat Genet. 2002; 32: 509-514.
61. Yoshioka S, Takahashi Y, Okimura Y, et al. Gene expression profile in the heart of spontaneous dwarf rat: in vivo effects of growth hormone. Biochem Biophys Res Commun. 2006; 341: 88-93.
62. Maier M, Milz S, Wirtz DC, Rompe JD, Schmitz C. Basic research of applying extracorporeal shockwaves on the musculoskeletal system. An assessment of current status. Orthopade. 2002; 31: 667-677.
63. Hofmann A, Hessmann MH, Meurer A, Rommens PM, Heine J, Rompe JD. Extracorporeal shock wave induced changes in function of osteoblast-like cells. In: Proceedings of American Academy of Orthopaedic Surgeons (AAOS). Rosemont, IL: American Academy of Orthopaedic Surgeons; 2005.
64. Kusnierczak D, Brocai DR, Vettel U, Loew M. Effect of extracorporeal shockwave administration on biological behavior of bone cells in vitro. Z Orthop Ihre Grenzgeb. 2000; 138: 29-33.
65. Laudone VP, Morgan TR, Huryk RF, Heston WD, Fair WR. Cytotoxicity of high energy shock waves: methodologic considerations. J Urol. 1989; 141: 965-968.
66. Kaver I, Koontz WW Jr, Wilson JD, Guice JM, Smith MJ. Effects of lithotripter-generated high energy shock waves of mammalian cells in vitro. J Urol. 1992; 147: 215-219.
67. Smits GA, Oosterhof GO, de Ruyter AE, Schalken JA, Debruyne FM. Cytotoxic effects of high energy shock waves in different in vitro models: influence of the experimental set-up. J Urol. 1991; 145: 171-175.