Microvascular endothelial function in obstructive sleep apnea: Impact of continuous positive airway pressure and mandibular advancement

Sleep Medicine

Volumn 10, Issue 7, 2009, Pages 746-752

  Trzepizur, Wojciech ^a   Gagnadoux, Frédéric ^a,b   Abraham, Pierre ^a,b   Rousseau, Pascal ^a   Meslier, Nicole ^a,b   Saumet, Jean Louis ^a,c   Racineux, Jean Louis ^a  

^a ANGERS UNIVERSITY HOSPITAL   (France)

^b Universite d'Angers   (France)

^c UNIVERSITÉ LYON 1   (France)

Author keywords

Continuous positive airway pressure; Endothelial dysfunction; Mandibular advancement; Microcirculation; Obstructive sleep apnea syndrome; Treatment

Indexed keywords

ACETYLCHOLINE; CANDESARTAN; CICLETANINE; METFORMIN; NEBIVOLOL; NITROPRUSSIDE SODIUM; TELMISARTAN; TRANDOLAPRIL;

ADULT; AGED; ARTICLE; BLOOD VESSEL REACTIVITY; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; FEMALE; HUMAN; HYPERTENSION; IONTOPHORESIS; JAW MOVEMENT; LASER DOPPLER FLOWMETRY; MALE; MANDIBLE; MICROANGIOPATHY; NIGHT SLEEP; NON INSULIN DEPENDENT DIABETES MELLITUS; OXYGEN SATURATION; POSITIVE END EXPIRATORY PRESSURE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SLEEP APNEA SYNDROME; TREATMENT DURATION; VASCULAR ENDOTHELIUM; VASODILATATION;

ADOLESCENT; ADULT; AGED; CONTINUOUS POSITIVE AIRWAY PRESSURE; CROSS-OVER STUDIES; ENDOTHELIUM, VASCULAR; HUMANS; MALE; MANDIBULAR ADVANCEMENT; MICROVESSELS; MIDDLE AGED; POLYSOMNOGRAPHY; RHEOLOGY; SEVERITY OF ILLNESS INDEX; SLEEP APNEA, OBSTRUCTIVE; VASODILATION; YOUNG ADULT;

EID: 67650616576     PISSN: 13899457     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.sleep.2008.06.013     Document Type: Article

References (33)

1. Young T., Palta M., Dempsey J., Skatrud J., Weber S., and Badr S. The occurrence of sleep-disordered breathing among middle-aged adults. N Engl J Med 328 (1993) 1230-1235
2. McNicholas W.T., and Bonsigore M.R. Sleep apnoea as an independent risk factor for cardiovascular disease: current evidence, basic mechanisms and research priorities. Eur Respir J 29 (2007) 156-178
3. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med 340 (1999) 115-126
4. Perticone F., Ceravolo R., Pujia A., Ventura G., Iacopino S., Scozzafava A., et al. Prognostic significance of endothelial dysfunction in hypertensive patients. Circulation 104 (2001) 191-196
5. Carlson J.T., Rangemark C., and Hedner J.A. Attenuated endothelium-dependent vascular relaxation in patients with sleep apnoea. J Hypertens 14 (1996) 577-584
6. Kato M., Roberts-Thomson P., Phillips B.G., Haynes W.G., Winnicki M., Accurso V., et al. Impairment of endothelium-dependent vasodilation of resistance vessels in patients with obstructive sleep apnea. Circulation 102 (2000) 2607-2610
7. Kraiczi H., Caidahl K., Samuelsson A., Peker Y., and Hedner J. Impairment of vascular endothelial function and left ventricular filling: association with the severity of apnea-induced hypoxemia during sleep. Chest 119 (2001) 1085-1091
8. Imadojemu V.A., Gleeson K., Quraishi S.A., Kunselman A.R., Sinoway L.I., and Leuenberger U.A. Impaired vasodilator responses in obstructive sleep apnea are improved with continuous positive airway pressure therapy. Am J Respir Crit Care Med 165 (2002) 950-953
9. Ip M.S., Tse H.F., Lam B., Tsang K.W., and Lam W.K. Endothelial function in obstructive sleep apnea and response to treatment. Am J Respir Crit Care Med 169 (2004) 348-353
10. Itzhaki S., Lavie L., Pillar G., Tal G., and Lavie P. Endothelial dysfunction in obstructive sleep apnea measured by peripheral arterial tone response in the finger to reactive hyperemia. Sleep 28 (2005) 594-600
11. Wiernsperger N., Nivoit P., and Bouskela E. Obstructive sleep apnea and insulin resistance: a role for microcirculation?. Clinics 61 (2006) 253-266
12. Giles T.L., Lasserson T.J., Smith B.H., White J., Wright J., and Cates C.J. Continuous positive airways pressure for obstructive sleep apnoea in adults. Cochrane Database Syst Rev 3 (2006) CD001106
13. Bazzano L.A., Khan Z., Reynolds K., and He J. ffect of nocturnal nasal continuous positive airway pressure on blood pressure in obstructive sleep apnea. Hypertension 50 (2007) 417-423
14. Lattimore J.L., Wilcox I., Skilton M., Langenfeld M., and Celermajer D.S. Treatment of obstructive sleep apnoea leads to improved microvascular endothelial function in the systemic circulation. Thorax 61 (2006) 491-495
15. Pepin J.L., Leger P., Veale D., Langevin B., Robert D., and Levy P. Side effects of nasal continuous positive airway pressure in sleep apnea syndrome. Study of 193 patients in two French sleep centers. Chest 107 (1995) 375-381
16. Engleman H.M., and Wild M.R. Improving CPAP use by patients with the sleep apnoea/hypopnoea syndrome (SAHS). Sleep Med Rev 7 (2003) 81-99
17. McArdle N., Devereux G., Heidarnejad H., Engleman H.M., Mackay T.W., and Douglas N.J. Long-term use of CPAP therapy for sleep apnea/hypopnea syndrome. Am J Respir Crit Care Med 159 (1999) 1108-1114
18. Lim J., Lasserson T.J., Fleetham J., and Wright J. Oral appliances for obstructive sleep apnoea. Cochrane Database Syst Rev (2006) CD004435
19. Ferguson K.A., Cartwright R., Rogers R., and Schmidt-Nowara W. Oral appliances for snoring and obstructive sleep apnea: a review. Sleep 29 (2006) 244-262
20. Barnes M., McEvoy R.D., Banks S., Tarquinio N., Murray C.G., Vowles N., et al. Efficacy of positive airway pressure and oral appliance in mild to moderate obstructive sleep apnea. Am J Respir Crit Care Med 170 (2004) 656-664
21. Gotsopoulos H., Kelly J.J., and Cistulli P.A. Oral appliance therapy reduces blood pressure in obstructive sleep apnea: a randomized, controlled trial. Sleep 27 (2004) 934-941
22. Itzhaki S., Dorchin H., Clark G., Lavie L., Lavie P., and Pillar G. The effects of 1-year treatment with a herbst mandibular advancement splint on obstructive sleep apnea, oxidative stress, and endothelial function. Chest 131 (2007) 740-749
23. Taddei S., Virdis A., Mattei P., Ghiadoni L., Gennari A., Fasolo C.B., et al. Aging and endothelial function in normotensive subjects and patients with essential hypertension. Circulation 91 (1995) 1981-1987
24. Koitka A., Abraham P., Bouhanick B., Sigaudo-Roussel D., Demiot C., and Saumet J.L. Impaired pressure-induced vasodilation at the foot in young adults with type 1 diabetes. Diabetes 53 (2004) 721-725
25. Rousseau P., Tartas M., Fromy B., Godon A., Custaud M.A., Saumet J.L., et al. Platelet inhibition by low-dose aspirin but not by clopidogrel reduces the axon-reflex current-induced vasodilation in humans. Am J Physiol Regul Integr Comp Physiol 294 (2008) R1420-R1426
26. Johns M.W. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 14 (1991) 540-545
27. Pelletier-Fleury N., Meslier N., Gagnadoux F., Person C., Rakotonanahary D., Ouksel H., et al. Economic arguments for the immediate management of moderate-to-severe obstructive sleep apnoea syndrome. Eur Respir J 23 (2004) 53-60
28. Sleep-related breathing disorders in adults: recommendations for syndrome definition and measurement techniques in clinical research. The Report of an American Academy of Sleep Medicine Task Force. Sleep 1999;22:667-689.
29. Petelle B., Vincent G., Gagnadoux F., Rakotonanahary D., Meyer B., and Fleury B. One-night mandibular advancement titration for obstructive sleep apnea syndrome: a pilot study. Am J Respir Crit Care Med 165 (2002) 1150-1153
30. Phillips S.A., Olson E.B., Morgan B.J., and Lombard J.H. Chronic intermittent hypoxia impairs endothelium-dependent dilation in rat cerebral and skeletal muscle resistance arteries. Am J Physiol Heart Circ Physiol 286 (2004) H388-H393
31. Ip M.S., Lam B., Chan L.Y., Zheng L., Tsang K.W., Fung P.C., et al. Circulating nitric oxide is suppressed in obstructive sleep apnea and is reversed by nasal continuous positive airway pressure. Am J Respir Crit Care Med 162 (2000) 2166-2171
32. Rauscher H., Formanek D., Popp W., and Zwick H. Self-reported vs measured compliance with nasal CPAP for obstructive sleep apnea. Chest 103 (1993) 1675-1680
33. Cross M.D., Mills N.L., Al-Abri M., Riha R.L., Vennelle M., McKay T.W., et al. Continuous positive airway pressure improves vascular function in obstructive sleep apnea hypopnea syndrome: a randomized controlled trial. Thorax (2008)