메뉴 건너뛰기




Volumn 37, Issue 4, 2009, Pages 1486-1487

Antithrombosis trials: Should we test therapeutic heparin adjusted based on activated partial thromboplastin time in septic shock?

Author keywords

Heparin; Sepsis; Treatment

Indexed keywords

ANTITHROMBIN III; DROTRECOGIN; HEPARIN; PLACEBO; TISSUE FACTOR PATHWAY INHIBITOR;

EID: 67650504236     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31819d2bb4     Document Type: Editorial
Times cited : (2)

References (20)
  • 1
    • 0035826096 scopus 로고    scopus 로고
    • Efficacy and safety of recombinant human activated protein C for severe sepsis
    • Bernard GR, Vincent JL, Laterre PF, et al: Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 2001; 344:699-709
    • (2001) N Engl J Med , vol.344 , pp. 699-709
    • Bernard, G.R.1    Vincent, J.L.2    Laterre, P.F.3
  • 2
    • 0035904368 scopus 로고    scopus 로고
    • Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: A randomized controlled trial
    • Warren BL, Eid A, Singer P, et al: Caring for the critically ill patient. High-dose antithrombin III in severe sepsis: A randomized controlled trial. JAMA 2001; 286: 1869-1878
    • (2001) JAMA , vol.286 , pp. 1869-1878
    • Warren, B.L.1    Eid, A.2    Singer, P.3
  • 4
    • 0038690407 scopus 로고    scopus 로고
    • Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: A randomized controlled trial
    • Abraham E, Reinhart K, Opal S, et al: Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: A randomized controlled trial. JAMA 2003; 290:238-247
    • (2003) JAMA , vol.290 , pp. 238-247
    • Abraham, E.1    Reinhart, K.2    Opal, S.3
  • 5
    • 67650470156 scopus 로고    scopus 로고
    • Unfractioned heparin for treatment of sepsis: A randomized clinical trial (The HETRASE Study)
    • Jaimes F, De La Rosa G, Morales C, et al: Unfractioned heparin for treatment of sepsis: A randomized clinical trial (The HETRASE Study). Crit Care Med 2009; 37:1185-1196
    • (2009) Crit Care Med , vol.37 , pp. 1185-1196
    • Jaimes, F.1    De La Rosa, G.2    Morales, C.3
  • 6
    • 31344478995 scopus 로고    scopus 로고
    • Antithrombotic therapies for sepsis: A need for more studies
    • Minneci PC, Deans KJ, Cui X, et al: Antithrombotic therapies for sepsis: A need for more studies. Crit Care Med 2006; 34: 538-541
    • (2006) Crit Care Med , vol.34 , pp. 538-541
    • Minneci, P.C.1    Deans, K.J.2    Cui, X.3
  • 7
    • 45949086068 scopus 로고    scopus 로고
    • Hirsh J, Bauer KA, Donati MB, et al: Parenteral anticoagulants: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133(6 Suppl):141S-159S
    • Hirsh J, Bauer KA, Donati MB, et al: Parenteral anticoagulants: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines (8th Edition). Chest 2008; 133(6 Suppl):141S-159S
  • 8
    • 56049115814 scopus 로고    scopus 로고
    • Early intravenous unfractionated heparin and mortality in septic shock
    • Zarychanski R, Doucette S, Fergusson D, et al: Early intravenous unfractionated heparin and mortality in septic shock. Crit Care Med 2008; 36:2973-2979
    • (2008) Crit Care Med , vol.36 , pp. 2973-2979
    • Zarychanski, R.1    Doucette, S.2    Fergusson, D.3
  • 9
    • 25444492831 scopus 로고    scopus 로고
    • Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death
    • Abraham E, Laterre PF, Garg R, et al: Drotrecogin alfa (activated) for adults with severe sepsis and a low risk of death. N Engl J Med 2005; 353:1332-1341
    • (2005) N Engl J Med , vol.353 , pp. 1332-1341
    • Abraham, E.1    Laterre, P.F.2    Garg, R.3
  • 10
    • 0035159740 scopus 로고    scopus 로고
    • Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: A multicenter, randomized, placebo-controlled, single-blind, dose escalation study
    • Abraham E, Reinhart K, Svoboda P, et al: Assessment of the safety of recombinant tissue factor pathway inhibitor in patients with severe sepsis: A multicenter, randomized, placebo-controlled, single-blind, dose escalation study. Crit Care Med 2001; 29: 2081-2089
    • (2001) Crit Care Med , vol.29 , pp. 2081-2089
    • Abraham, E.1    Reinhart, K.2    Svoboda, P.3
  • 11
    • 7144251856 scopus 로고    scopus 로고
    • Antithrombin III (ATIII) replacement therapy in patients with sepsis and/or postsurgical complications: A controlled double-blind, randomized, multicenter study
    • Baudo F, Caimi TM, de Cataldo F, et al: Antithrombin III (ATIII) replacement therapy in patients with sepsis and/or postsurgical complications: A controlled double-blind, randomized, multicenter study. Intensive Care Med 1998; 24:336-342
    • (1998) Intensive Care Med , vol.24 , pp. 336-342
    • Baudo, F.1    Caimi, T.M.2    de Cataldo, F.3
  • 12
    • 0035164538 scopus 로고    scopus 로고
    • Safety and dose relationship of recombinant human activated protein C for coagulopathy in severe sepsis
    • Bernard GR, Ely EW, Wright TJ, et al: Safety and dose relationship of recombinant human activated protein C for coagulopathy in severe sepsis. Crit Care Med 2001; 29: 2051-2059
    • (2001) Crit Care Med , vol.29 , pp. 2051-2059
    • Bernard, G.R.1    Ely, E.W.2    Wright, T.J.3
  • 13
    • 0031825290 scopus 로고    scopus 로고
    • Antithrombin III in patients with severe sepsis. A randomized, placebo-controlled, double-blind multicenter trial plus a meta-analysis on all randomized, placebo-controlled, doubleblind trials with antithrombin III in severe sepsis
    • Eisele B, Lamy M, Thijs LG, et al: Antithrombin III in patients with severe sepsis. A randomized, placebo-controlled, double-blind multicenter trial plus a meta-analysis on all randomized, placebo-controlled, doubleblind trials with antithrombin III in severe sepsis. Intensive Care Med 1998; 24:663-672
    • (1998) Intensive Care Med , vol.24 , pp. 663-672
    • Eisele, B.1    Lamy, M.2    Thijs, L.G.3
  • 14
    • 0027171963 scopus 로고
    • Doubleblind, placebo-controlled trial of antithrombin III concentrates in septic shock with disseminated intravascular coagulation
    • Fourrier F, Chopin C, Huart JJ, et al: Doubleblind, placebo-controlled trial of antithrombin III concentrates in septic shock with disseminated intravascular coagulation. Chest 1993; 104:882-888
    • (1993) Chest , vol.104 , pp. 882-888
    • Fourrier, F.1    Chopin, C.2    Huart, J.J.3
  • 15
    • 0031266015 scopus 로고    scopus 로고
    • Antithrombin III supplementation in severe sepsis: Beneficial effects on organ dysfunction
    • Inthorn D, Hoffmann JN, Hartl WH, et al: Antithrombin III supplementation in severe sepsis: Beneficial effects on organ dysfunction. Shock 1997; 8:328-334
    • (1997) Shock , vol.8 , pp. 328-334
    • Inthorn, D.1    Hoffmann, J.N.2    Hartl, W.H.3
  • 16
    • 33847687731 scopus 로고    scopus 로고
    • Drotrecogin alfa (activated) in children with severe sepsis: A multicentre phase III randomised controlled trial
    • Nadel S, Goldstein B, Williams MD, et al: Drotrecogin alfa (activated) in children with severe sepsis: A multicentre phase III randomised controlled trial. Lancet 2007; 369: 836-843
    • (2007) Lancet , vol.369 , pp. 836-843
    • Nadel, S.1    Goldstein, B.2    Williams, M.D.3
  • 17
    • 0003143460 scopus 로고
    • Prospective, double-blind, placebocontrolled, trial of ATIII substitution in sepsis
    • Balk RA, Bedrosian C, McCormick L, et al: Prospective, double-blind, placebocontrolled, trial of ATIII substitution in sepsis. Intensive Care Med 1995; 21(Suppl 1): S17
    • (1995) Intensive Care Med , vol.21 , Issue.SUPPL. 1
    • Balk, R.A.1    Bedrosian, C.2    McCormick, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.