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Volumn 37, Issue 10, 2008, Pages 1048-1049

Reaction between guanidine hydroehloride and chalcones: An efficient solvent-free synthesis of 2,4,6-triarylpyridines under microwave irradiation

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EID: 67650497402     PISSN: 03667022     EISSN: 13480715     Source Type: Journal    
DOI: 10.1246/cl.2008.1048     Document Type: Article
Times cited : (13)

References (40)
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    • M. Balasubramanian, J. G. Keay, in Comprehensive Heterocyclic Chemistry II, ed. by A. R. Katritzky, C. W. Rees, E. V. F. Scriven, Pergamon Press, London, 1996, Vol. 5, Chap. 6, pp. 245-300, and references therein.
    • (1996) Comprehensive Heterocyclic Chemistry II , vol.5 , pp. 245-300
    • Balasubramanian, M.1    Keay, J.G.2
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    • Chem Ahstr. 1996, 125, 167792w.
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    • ed. by A. R. Katritzky, C. W. Rees, E. V. F. Scriven, Pergamon Press, London, Chap. 2, pp
    • K. Undheim, T. Benneche, in Comprehensive Heterocyclic Chemistry II, ed. by A. R. Katritzky, C. W. Rees, E. V. F. Scriven, Pergamon Press, London, 1996, Vol. 6, Chap. 2, pp. 93-231;
    • (1996) Comprehensive Heterocyclic Chemistry II , vol.6 , pp. 93-231
    • Undheim, K.1    Benneche, T.2
  • 37
    • 67650436903 scopus 로고    scopus 로고
    • General procedure for the preparation of compounds 3: A mixture of 1 (2mmol) and guanidine hydrochloride (0.24 g, 2.5 mmol) ground using a mortar and pestle. Then the mixture was irradiated in a microwave oven (ETHOS 1600, Milestone with a power of 600 W) at 180°C for 5 min. Then the reaction mixture cooled to room temperature and the crude solid obtained washed with water and recrys-tallized from absolute ethanol.
    • General procedure for the preparation of compounds 3: A mixture of 1 (2mmol) and guanidine hydrochloride (0.24 g, 2.5 mmol) ground using a mortar and pestle. Then the mixture was irradiated in a microwave oven (ETHOS 1600, Milestone with a power of 600 W) at 180°C for 5 min. Then the reaction mixture cooled to room temperature and the crude solid obtained washed with water and recrys-tallized from absolute ethanol.


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