Synthesis of novel pyrazole derivatives and evaluation of their antidepressant and anticonvulsant activities

European Journal of Medicinal Chemistry

Volumn 44, Issue 9, 2009, Pages 3480-3487

  Abdel Aziz, Mohamed ^a   Abuo Rahma, Gamal El Din A ^a   Hassan, Alaa A ^b  

^a Minia University   (Egypt)

^b NONE   (Egypt)

Author keywords

Anticonvulsant; Antidepressant; Carboxylic acid hydrazides; Oxadiazole derivatives; Pyrazole

Indexed keywords

ETHYL 1 (1H INDOLE 2 CARBONYL) 4 CYANO 5 OXO 2,5 DIHYDRO 1H PYRAZOLE 3 CARBOXYLATE; ETHYL 1 (THIOPHENE 2 CARBONYL) 4 CYANO 5 OXO 2,5 DIHYDRO 1H PYRAZOLE 3 CARBOXYLATE; ETHYL 1 BENZOYL 4 CYANO 5 OXO 2,5 DIHYDRO 1H PYRAZOLE 3 CARBOXYLATE; IMIPRAMINE; N' (THIOPHENE 2 CARBONYL)THIOPHEN 2 CARBOHYDRAZIDE; N' BENZOYLBENZOHYDRAZIDE; PHENOBARBITAL; PHENYTOIN; PYRAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTICONVULSANT ACTIVITY; ARTICLE; CHEMICAL REACTION; CLONIC SEIZURE; CONTROLLED STUDY; DRUG SYNTHESIS; MALE; MOUSE; NONHUMAN;

ANIMALS; ANTICONVULSANTS; ANTIDEPRESSIVE AGENTS; BEHAVIOR, ANIMAL; HINDLIMB SUSPENSION; MICE; PYRAZOLES; SEIZURES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 67650493170     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2009.01.032     Document Type: Article

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