Mixed medullary-papillary carcinoma of the thyroid: Report of a case and review of the literature

Head and Neck

Volumn 31, Issue 7, 2009, Pages 968-974

  Nangue, Charlette ^a,b   Bron, Luc ^a   Portmann, Luc ^a   Volante, Marco ^c   Ris, Hans Beat ^a   Monnier, Philippe ^a   Andrejevic Blant, Snezana ^a  

^a LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^b Faculty of Medicine and Biomedical Sciences   (Cameroon)

^c UNIVERSITY OF TURIN   (Italy)

Author keywords

Calcitonin; Lymph node; Medisatinal dissection; Mixed medullary papillary carcinoma; Thyroid

Indexed keywords

CALCITONIN; CARCINOEMBRYONIC ANTIGEN; FLUORODEOXYGLUCOSE F 18;

ADULT; ARTICLE; ASPIRATION BIOPSY; ASPIRATION CYTOLOGY; CALCITONIN BLOOD LEVEL; CANCER DIAGNOSIS; CASE REPORT; CLINICAL FEATURE; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; LYMPH NODE DISSECTION; LYMPH NODE METASTASIS; NECK DISSECTION; PAIN; PAPILLARY CARCINOMA; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SUBSTITUTION THERAPY; THYROID MEDULLARY CARCINOMA; THYROIDECTOMY; TUMOR VOLUME; ULTRASOUND;

ADULT; CARCINOMA, MEDULLARY; CARCINOMA, PAPILLARY; FEMALE; HUMANS; MIXED TUMOR, MALIGNANT; THYROID NEOPLASMS; THYROIDECTOMY;

EID: 67650470939     PISSN: 10433074     EISSN: 10970347     Source Type: Journal    
DOI: 10.1002/hed.20984     Document Type: Article

References (19)

1. Hales M, Rosenau W, Okerlund MD, Galante M. Carcinoma of the thyroid with a mixed medullary and follicular pattern: morphologic, immunohistochemical, and clinical laboratory studies. Cancer 1982;50:1352-1359. (Pubitemid 12031960)
2. Pfaltz M, Hedinger CE, Muhlethaler JP. Mixed medullary and follicular carcinoma of the thyroid. Virchows Arch A Pathol Anat Histopathol 1983;400:53-59.
3. Papotti M, Negro F, Carney JA, Bussolati G, Lloyd RV. Mixed medullary-follicular carcinoma of the thyroid. Amorphological, immunohistochemical and in situ hybridization analysis of 11 cases. Virchows Arch 1997;430: 397-405.
4. Papotti M, Volante M, Komminoth P, Sobrinho-Simoes M, Bussolati G. Thyroid carcinomas with mixed follicular and C-cell differentiation patterns. Semin Diagn Pathol 2000;17:109-119. (Pubitemid 30322272)
5. Papotti M, Bussolati B, Komminoth P, Matias-Guiu X, Volante M. Mixed medullary and follicular cell carcinoma. In: DeLellis R, Lloyd R, Heitz P, Eng C, editors. Pathology and genetic of tumour of endocrine organs. Lyon: IARC Press; 2004. pp 92-94.
6. Apel RL, Alpert LC, Rizzo A, LiVolsi VA, Asa SL. A metastasizing composite carcinoma of the thyroid with distinct medullary and papillary components. Arch Pathol Lab Med 1994;118:1143-1147. (Pubitemid 24345843)
7. Ljungberg O, Ericsson UB, Bondeson L, Thorell J. A compound follicular-parafollicular cell carcinoma of the thyroid: a new tumor entity? Cancer 1983;52:1053-1061.
8. Volante M, Papotti M, Roth J, et al. Mixed medullary-follicular thyroid carcinoma. Molecular evidence for a dual origin of tumor components. Am J Pathol 1999;155:1499-1509.
9. Andrejevic-Blant S, Osterheld MC, Caron L, Ballini JP, Monnier P. Deoxyribonucleic acid content as an indicator of progression of squamous cell carcinogenesis in the esophagus: comparative analysis on imprint-cytospin and tissue section preparation. Cancer Detect Prev 2006;30:276-283. (Pubitemid 44163054)
10. Lax SF, Beham A, Kronberger-Schonecker D, Langsteger W, Denk H. Coexistence of papillary and medullary carcinoma of the thyroid gland-mixed or collision tumour? Clinicopathological analysis of three cases. Virchows Arch 1994;424:441-447. (Pubitemid 24185399)
11. Kovacs CS, Mase RM, Kovacs K, Nguyen GK, Chik CL. Thyroid medullary carcinoma with thyroglobulin immunoreactivity in sporadic multiple endocrine neoplasia type 2-B. Cancer 1994;74:928-932. (Pubitemid 24237475)
12. Mizukami Y, Nonomura A, Michigishi T, Noguchi M, Ishizaki T. Mixed medullary-follicular carcinoma of the thyroid gland: a clinicopathologic variant of medullary thyroid carcinoma. Mod Pathol 1996;9:631-635. (Pubitemid 26227563)
13. Noel M, Delehaye MC, Segond N, et al. Study of calcitonin and thyroglobulin gene expression in human mixed follicular and medullary thyroid carcinoma. Thyroid 1991;1:249-256.
14. Seki T, Kameyama K, Hayashi H, et al. Composite metastatic carcinoma in lymph nodes of patients with concurrent medullary and papillary thyroid carcinoma: a report of two cases. Endocr Pathol 2004;15:83-88. (Pubitemid 38951812)
15. Holm R, Sobrinho Simoes M, Nesland J. Medullary thyroid carcinoma with thyroglobulin immunoreactivity. A special entity? Lab Invest 1987;57:258-268.
16. Johnston D, Hatzis D, Sunday M. Expression of v-Haras driven by the calcitonin/calcitonin gene-related peptide promoter: a novel transgenic murine model for medullary thyroid carcinoma. Oncogene 1998;16:167-177. (Pubitemid 28045102)
17. Zhang P, Zuo H, Ozaki T, Nakagomi N, Kakudo K. Cancer stem cell hypothesis in thyroid cancer. Pathol Int 2006;56:485-489. (Pubitemid 44258848)
18. Burstein DE, Nagi C, Wang BY, Unger P. Immunohistochemical detection of p53 homolog p63 in solid cell nests, papillary thyroid carcinoma, and Hashimoto's thyroiditis: a stem cell hypothesis of papillary carcinoma oncogenesis. Hum Pathol 2004;35:465-473. (Pubitemid 38507084)
19. Preto A, Cameselle-Teijeiro J, Moldes-Boullosa J, et al. Telomerase expression and proliferative activity suggest a stem cell role for thyroid solid cell nests. Mod Pathol 2004;17:819-826. (Pubitemid 38849387)