-
1
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A, Siegel R, Ward E, et al. Cancer statistics, 2008. CA Cancer. J Clin 2008;58:71-96
-
(2008)
CA Cancer. J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
-
2
-
-
0032756946
-
The changing epidemiology of esophageal cancer
-
Blot WJ, Mclaughlin JK. The changing epidemiology of esophageal cancer. Semin Oncol 1999;26:2-8
-
(1999)
Semin Oncol
, vol.26
, pp. 2-8
-
-
Blot, W.J.1
Mclaughlin, J.K.2
-
3
-
-
20044366529
-
Paclitaxel-based chemoradiotherapy in localized gastric carcinoma: Degree of pathologic response and not clinical parameters dictated patient outcome
-
Ajani JA, Mansfield PF, Crane CH, et al. Paclitaxel-based chemoradiotherapy in localized gastric carcinoma: degree of pathologic response and not clinical parameters dictated patient outcome. J Clin Oncol 2005;23:1237-44
-
(2005)
J Clin Oncol
, vol.23
, pp. 1237-1244
-
-
Ajani, J.A.1
Mansfield, P.F.2
Crane, C.H.3
-
4
-
-
27744478033
-
Neoadjuvant radiochemotherapy for locally advanced gastric cancer: Long-term results of a phase I trial
-
Allal AS, Zwahlen D, Brundler MA, et al. Neoadjuvant radiochemotherapy for locally advanced gastric cancer: long-term results of a phase I trial. Int J Radiat Oncol Biol Phys 2005;63:1286-9
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.63
, pp. 1286-1289
-
-
Allal, A.S.1
Zwahlen, D.2
Brundler, M.A.3
-
5
-
-
19644396607
-
Role of post-operative chemoradiation in resected gastric cancer
-
MacDonald JS. Role of post-operative chemoradiation in resected gastric cancer. J Surg Oncol 2005;90:166-70
-
(2005)
J Surg Oncol
, vol.90
, pp. 166-170
-
-
MacDonald, J.S.1
-
6
-
-
27744437443
-
An observational study suggesting clinical benefit for adjuvant postoperative chemoradiation in a population of over 500 cases after gastric resection with D2 nodal dissection for adenocarcinoma of the stomach
-
Kim S, Lim do H, Lee J, et al. An observational study suggesting clinical benefit for adjuvant postoperative chemoradiation in a population of over 500 cases after gastric resection with D2 nodal dissection for adenocarcinoma of the stomach. Int J Radiat Oncol Biol Phys 2005;63:1279-85
-
(2005)
Int J Radiat Oncol Biol Phys
, vol.63
, pp. 1279-1285
-
-
Kim, S.1
Lim do, H.2
Lee, J.3
-
7
-
-
0041674886
-
Perioperative chemotherapy in operable gastric and lower oesophageal cancer: A randomized, controlled trial (the MAGIC trial, ISRCTN 93793971) [abstract 998]
-
Allum W, Cunningham D, Weeden S, et al. Perioperative chemotherapy in operable gastric and lower oesophageal cancer: a randomized, controlled trial (the MAGIC trial, ISRCTN 93793971) [abstract 998]. Proc ASCO 2008;22:249a
-
(2008)
Proc ASCO
, vol.22
-
-
Allum, W.1
Cunningham, D.2
Weeden, S.3
-
8
-
-
19444377245
-
Gastrointestinal cancer: Recent developments in medical oncology
-
Chong G, Cunningham D. Gastrointestinal cancer: recent developments in medical oncology. Eur J Surg Oncol 2005;31:453-60
-
(2005)
Eur J Surg Oncol
, vol.31
, pp. 453-460
-
-
Chong, G.1
Cunningham, D.2
-
9
-
-
0027217474
-
Modified therapy with 5-fluorouracil, doxorubicin, and methotrexate in advanced gastric cancer
-
Murad AM, Santiago FF, Petroianu A, et al. Modified therapy with 5-fluorouracil, doxorubicin, and methotrexate in advanced gastric cancer. Cancer 1993;72:37-41
-
(1993)
Cancer
, vol.72
, pp. 37-41
-
-
Murad, A.M.1
Santiago, F.F.2
Petroianu, A.3
-
10
-
-
0028959887
-
Randomized comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) pls supportive care with supportive care alone in patients with non-resectable gastric cancer
-
Pyrhonen S, Kuitunen T, Nyandoto P, Kouri M. Randomized comparison of fluorouracil, epidoxorubicin and methotrexate (FEMTX) pls supportive care with supportive care alone in patients with non-resectable gastric cancer. Br J Cancer 1995;71:587-91
-
(1995)
Br J Cancer
, vol.71
, pp. 587-591
-
-
Pyrhonen, S.1
Kuitunen, T.2
Nyandoto, P.3
Kouri, M.4
-
11
-
-
0002074953
-
Palliative chemotherapy versus supportive care in patients with metastatic gastric cancer a randomized trial
-
Köln, Germany
-
Scheithauer W, Kornek G, Zeh B, et al. Palliative chemotherapy versus supportive care in patients with metastatic gastric cancer a randomized trial. Proceedings of the Second International Conference on Biology, Prevention and treatment of GI Malignancy. Köln, Germany, 1995;68
-
(1995)
Proceedings of the Second International Conference on Biology, Prevention and treatment of GI Malignancy
, pp. 68
-
-
Scheithauer, W.1
Kornek, G.2
Zeh, B.3
-
12
-
-
8044236424
-
Randomized comparison between chemotherapy plus best supportive care with best supportive care in advanced gastric cancer
-
Grimelius B, Ekstrom K, Hoffman K, et al. Randomized comparison between chemotherapy plus best supportive care with best supportive care in advanced gastric cancer. Ann Oncol 1997;8:163-8
-
(1997)
Ann Oncol
, vol.8
, pp. 163-168
-
-
Grimelius, B.1
Ekstrom, K.2
Hoffman, K.3
-
13
-
-
33745547767
-
Chemotherapy in advanced gastric cancer : A systematic review and meta-analysis based on aggregate data
-
Wagner AD, Grothe W, Haerting J, et al. Chemotherapy in advanced gastric cancer : a systematic review and meta-analysis based on aggregate data. J Clin Oncol 2006;24:2903-9
-
(2006)
J Clin Oncol
, vol.24
, pp. 2903-2909
-
-
Wagner, A.D.1
Grothe, W.2
Haerting, J.3
-
14
-
-
0031022803
-
Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer)
-
Webb A, Cunningham D, Scarffe JH, et al. Randomized trial comparing epirubicin, cisplatin, and fluorouracil versus fluorouracil, doxorubicin, and methotrexate in advanced esophagogastric cancer). J Clin Oncol 1997;15:261-7
-
(1997)
J Clin Oncol
, vol.15
, pp. 261-267
-
-
Webb, A.1
Cunningham, D.2
Scarffe, J.H.3
-
15
-
-
33750949065
-
Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: A report of the V325 study group
-
Van CustemE, Moiseyenko M, Tjulandin S, et al. Phase III study of docetaxel and cisplatin plus fluorouracil compared with cisplatin and fluorouracil as first-line therapy for advanced gastric cancer: a report of the V325 study group. J Clin Oncol 2006;24:4991-7
-
(2006)
J Clin Oncol
, vol.24
, pp. 4991-4997
-
-
CustemE, V.1
Moiseyenko, M.2
Tjulandin, S.3
-
16
-
-
38049047178
-
Capecitabine and oxaliplatin in advanced esophagogastric cancer
-
Cunningham D, Starling N, Rao S, et al. Capecitabine and oxaliplatin in advanced esophagogastric cancer. New Engl J Med 2008;358:36-46
-
(2008)
New Engl J Med
, vol.358
, pp. 36-46
-
-
Cunningham, D.1
Starling, N.2
Rao, S.3
-
17
-
-
0028955388
-
Epidermal growth factor-related peptides and their receptors in human malignancies
-
Salomon DS, Brandt R, Ciardiello F, et al. Epidermal growth factor-related peptides and their receptors in human malignancies. Crit Rev Oncol Hematol 1995;19:183-232
-
(1995)
Crit Rev Oncol Hematol
, vol.19
, pp. 183-232
-
-
Salomon, D.S.1
Brandt, R.2
Ciardiello, F.3
-
18
-
-
34250630933
-
Epidermal growth factor receptor (EGFR) expression is associated with a worse prognosis in gastric cancer patients undergoing curative surgery
-
Galizia G, Lieto E, Orditura M, et al. Epidermal growth factor receptor (EGFR) expression is associated with a worse prognosis in gastric cancer patients undergoing curative surgery. World J Surg 2007;31:1458-68
-
(2007)
World J Surg
, vol.31
, pp. 1458-1468
-
-
Galizia, G.1
Lieto, E.2
Orditura, M.3
-
19
-
-
38049177080
-
Expression of vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) is an independent prognostic indicator of worse outcome in gastric cancer patients
-
Lieto E, Ferraraccio F, Orditura M, et al. Expression of vascular endothelial growth factor (VEGF) and epidermal growth factor receptor (EGFR) is an independent prognostic indicator of worse outcome in gastric cancer patients. Ann Surg Oncol 2008;15:69-79
-
(2008)
Ann Surg Oncol
, vol.15
, pp. 69-79
-
-
Lieto, E.1
Ferraraccio, F.2
Orditura, M.3
-
20
-
-
0028907863
-
Clinical significance of epidermal growth factor (EGF), EGF receptor, and c-erbB-2 in human gastric cancer
-
Tokunaga A, Onda M, Okuda T, et al. Clinical significance of epidermal growth factor (EGF), EGF receptor, and c-erbB-2 in human gastric cancer. Cancer 1995;75:1418-25
-
(1995)
Cancer
, vol.75
, pp. 1418-1425
-
-
Tokunaga, A.1
Onda, M.2
Okuda, T.3
-
21
-
-
0242610317
-
Expression of epidermal growth factor receptor in gastric carcinomas
-
Takehana T, Kunitomo K, Suzuki S, et al. Expression of epidermal growth factor receptor in gastric carcinomas. Clin Gastroenterol Hepatol 2003;1:438-45
-
(2003)
Clin Gastroenterol Hepatol
, vol.1
, pp. 438-445
-
-
Takehana, T.1
Kunitomo, K.2
Suzuki, S.3
-
22
-
-
33847663871
-
Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study)
-
Pinto C, Di Fabio F, Siena S, et al. Phase II study of cetuximab in combination with FOLFIRI in patients with untreated advanced gastric or gastroesophageal junction adenocarcinoma (FOLCETUX study). Ann of Oncol 2007;18:510-17
-
(2007)
Ann of Oncol
, vol.18
, pp. 510-517
-
-
Pinto, C.1
Di Fabio, F.2
Siena, S.3
-
23
-
-
67650409862
-
Cetuximab plus weekly oxaliplatin/5FU/FA (FUFOX) in 1st line metastatic gastric cancer. Final results from a multicenter phase II study of the AIO upper GI study group
-
abstract 4526
-
Lordick F, Lorenzen S, Hegewisch-becker S, et al. Cetuximab plus weekly oxaliplatin/5FU/FA (FUFOX) in 1st line metastatic gastric cancer. Final results from a multicenter phase II study of the AIO upper GI study group [abstract 4526]. Gastrointestinal (Noncolorectal) Cancer, 2007 ASCO Annual Meeting
-
Gastrointestinal (Noncolorectal) Cancer, 2007 ASCO Annual Meeting
-
-
Lordick, F.1
Lorenzen, S.2
Hegewisch-becker, S.3
-
24
-
-
55749102456
-
Biweekly oxaliplatin and irinotecan chemotherapy in advanced gastric cancer. A first-line multicenter phase II trial of the Arbeitsgemeinschaft Medikamentöse Tumortherapie (AGMT)
-
Wöll E, Kühr T, Eisterer W. Biweekly oxaliplatin and irinotecan chemotherapy in advanced gastric cancer. A first-line multicenter phase II trial of the Arbeitsgemeinschaft Medikamentöse Tumortherapie (AGMT). Anticancer Res 2008;28:2901-5
-
(2008)
Anticancer Res
, vol.28
, pp. 2901-2905
-
-
Wöll, E.1
Kühr, T.2
Eisterer, W.3
-
25
-
-
67650435957
-
Oxaliplatin, irinotecan and cetuximab in advanced gastric cancer. First results of a multicenter phase II trial (GTM Gastric-2)
-
abstract 15587, 30 May, 3 June, Chicago, IL, USA
-
Wöll E, Greil W, Eisterer M, et al. Oxaliplatin, irinotecan and cetuximab in advanced gastric cancer. First results of a multicenter phase II trial (GTM Gastric-2) [abstract 15587]. Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting, 30 May - 3 June, Chicago, IL, USA
-
Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting
-
-
Wöll, E.1
Greil, W.2
Eisterer, M.3
-
26
-
-
67650418003
-
Cetuximab with irinotecan/Na-Fa/5-FU as first-line treatment in advanced gastric cancer: Preliminary results of a nonrandomised multi-centre AIO phase II study
-
abstract 102, 27 January, Orlando, FL, USA
-
Moehler MH, Trarbach T, Seufferlein T, et al. Cetuximab with irinotecan/Na-Fa/5-FU as first-line treatment in advanced gastric cancer: preliminary results of a nonrandomised multi-centre AIO phase II study [abstract 102]. 2008 Gastrointestinal Cancers Symposium, ASCO 2008, 25 - 27 January, Orlando, FL, USA
-
2008 Gastrointestinal Cancers Symposium, ASCO 2008, 25
-
-
Moehler, M.H.1
Trarbach, T.2
Seufferlein, T.3
-
27
-
-
67650429826
-
A phase II study of cetuximab (Cetuximab) with cisplatin and capecitabine (Xeloda) as 1st line treatment in advanced gastric cancer
-
abstract 15663, 30 May, 3 June, Chicago, IL, USA
-
Zhang X, Xu J, Shen L, et al. A phase II study of cetuximab (Cetuximab) with cisplatin and capecitabine (Xeloda) as 1st line treatment in advanced gastric cancer [abstract 15663]. Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting, 30 May - 3 June, Chicago, IL, USA
-
Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting
-
-
Zhang, X.1
Xu, J.2
Shen, L.3
-
28
-
-
67650450334
-
Cetuximab in combination with cisplatin and docetaxel as first-line treatment in patients with locally advanced or metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma (Italian phase II DOCETUX study)
-
abstract 4575, 30 May, 3 June, Chicago, IL, USA
-
Pinto C, Di FABIO, F BARONE, et al. Cetuximab in combination with cisplatin and docetaxel as first-line treatment in patients with locally advanced or metastatic gastric or gastroesophageal junction (GEJ) adenocarcinoma (Italian phase II DOCETUX study) [abstract 4575]. Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting, 30 May - 3 June, Chicago, IL, USA
-
Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting
-
-
Pinto, C.1
FABIO, D.2
BARONE, F.3
-
29
-
-
67650441592
-
ATTAX2: Docetaxel plus cetuximab as second line treatment for docetaxelrefractory oesophago-gastric cancer. Final results of a multicentre phase II trial by the AGITG
-
abstract 15554, 30 May, 3 June, Chicago, IL, USA
-
Tebbutt NC, Sourjina T, Strickland AH, et al. " ATTAX2: docetaxel plus cetuximab as second line treatment for docetaxelrefractory oesophago-gastric cancer. Final results of a multicentre phase II trial by the AGITG [abstract 15554]. Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting, 30 May - 3 June, Chicago, IL, USA
-
Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting
-
-
Tebbutt, N.C.1
Sourjina, T.2
Strickland, A.H.3
-
30
-
-
51449124276
-
Phase I study of epirubicin, cisplatin and capecitabine plus matuzumab in previously untreated patients with advanced oesophagogastric cancer
-
Rao S, Starling N, Cunningham D. Phase I study of epirubicin, cisplatin and capecitabine plus matuzumab in previously untreated patients with advanced oesophagogastric cancer. Br J Cancer 2008;99:868-74
-
(2008)
Br J Cancer
, vol.99
, pp. 868-874
-
-
Rao, S.1
Starling, N.2
Cunningham, D.3
-
31
-
-
4143135982
-
Efficacy, tolerability and pharmacokinetics of gefitinib (ZD 1839) in pretreated patients with metastatic gastric cancer [abstract 1036]
-
Doi T, Koizumi W, Siena S, et al. Efficacy, tolerability and pharmacokinetics of gefitinib (ZD 1839) in pretreated patients with metastatic gastric cancer [abstract 1036]. Proc Am Soc Clin Oncol 2003;22:258
-
(2003)
Proc Am Soc Clin Oncol
, vol.22
, pp. 258
-
-
Doi, T.1
Koizumi, W.2
Siena, S.3
-
32
-
-
33847609654
-
Phase II trial of gefitinib for recurrent or metastatic esophageal or gastroesphageal junction (GEJ) cancer
-
Adelstein DJ, Rybicki LA, Carrol M, et al. Phase II trial of gefitinib for recurrent or metastatic esophageal or gastroesphageal junction (GEJ) cancer. Proc Gastrointest Am Soc Clin Oncol Symp 2005;85:A5
-
(2005)
Proc Gastrointest Am Soc Clin Oncol Symp
, vol.85
-
-
Adelstein, D.J.1
Rybicki, L.A.2
Carrol, M.3
-
33
-
-
33748987894
-
Pharmacodynamic studies of gefitinib in tumor biopsy specimens from patients with advanced gastric carcinoma
-
Kaptain S, Tan LK, Chen B, et al. Pharmacodynamic studies of gefitinib in tumor biopsy specimens from patients with advanced gastric carcinoma. JCO 2006;24:4309-316
-
(2006)
JCO
, vol.24
, pp. 4309-4316
-
-
Kaptain, S.1
Tan, L.K.2
Chen, B.3
-
35
-
-
50849105191
-
Expression of HER2 in gastric cancer: Comparison between protein expression and gene amplification using a new commercial kit [abstract 4053]
-
Yano T, Ochiai A, Doi T, et al. Expression of HER2 in gastric cancer: comparison between protein expression and gene amplification using a new commercial kit [abstract 4053]. J Clin Oncol 2004;22:14S
-
(2004)
J Clin Oncol
, vol.22
-
-
Yano, T.1
Ochiai, A.2
Doi, T.3
-
36
-
-
50849134281
-
HER2-positive advanced gastric cancer: Similar HER2-positivity levels to breast cancer [abstract 3541]
-
Lordick F, Bang YJ, Kang YK, et al. HER2-positive advanced gastric cancer: similar HER2-positivity levels to breast cancer [abstract 3541]. Eur J Cancer 2007;5:271
-
(2007)
Eur J Cancer
, vol.5
, pp. 271
-
-
Lordick, F.1
Bang, Y.J.2
Kang, Y.K.3
-
37
-
-
67650441594
-
Correlation between Her2/neu overexpression/amplification and clinicopathological parameters in advanced gastric cancer patients: A prospective study
-
abstract 89, 19, 21 January, Orlando, FL, USA;
-
Gravalos C, Márquez A, García-carbonero R, et al. Correlation between Her2/neu overexpression/amplification and clinicopathological parameters in advanced gastric cancer patients: a prospective study [abstract 89]. Gastrointestinal Cancers Symposium, 19 - 21 January 2007, Orlando, FL, USA;130
-
(2007)
Gastrointestinal Cancers Symposium
, pp. 130
-
-
Gravalos, C.1
Márquez, A.2
García-carbonero, R.3
-
38
-
-
67650395450
-
Incidence of gastric and gastro-esophageal cancer in the ToGA trial: Correlation with HER2 positivity (abstract 11)
-
Kang Y, Bang Y, Lordick F, et al. Incidence of gastric and gastro-esophageal cancer in the ToGA trial: correlation with HER2 positivity (abstract 11). Gastrointestinal Cancers Symposium. 2008;75
-
(2008)
Gastrointestinal Cancers Symposium
, pp. 75
-
-
Kang, Y.1
Bang, Y.2
Lordick, F.3
-
39
-
-
20044372721
-
Amplification of HER-2 in gastric carcinoma: Association with topoisomerase IIa gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab
-
Tanner M, Hollmen M, Junttila TT, et al. Amplification of HER-2 in gastric carcinoma: association with topoisomerase IIa gene amplification, intestinal type, poor prognosis and sensitivity to trastuzumab. Ann Oncol 2005;16:273-27
-
(2005)
Ann Oncol
, vol.16
, pp. 273-327
-
-
Tanner, M.1
Hollmen, M.2
Junttila, T.T.3
-
40
-
-
0026510285
-
Clinicopathological significance of c-erbB-2 protein expression in human gastric carcinoma
-
Tateishi M, Toda T, Minamisono Y, et al. Clinicopathological significance of c-erbB-2 protein expression in human gastric carcinoma. Surg Oncol 1992;49:209-12
-
(1992)
Surg Oncol
, vol.49
, pp. 209-212
-
-
Tateishi, M.1
Toda, T.2
Minamisono, Y.3
-
41
-
-
0027180843
-
Double immunostaining for c-erbB-2 and p53 in human stomach cancer cells
-
Sasano H, Date F, Imatani A, et al. Double immunostaining for c-erbB-2 and p53 in human stomach cancer cells. Hum Pathol 1993;24:584-9
-
(1993)
Hum Pathol
, vol.24
, pp. 584-589
-
-
Sasano, H.1
Date, F.2
Imatani, A.3
-
42
-
-
0027436752
-
Overexpression of c-erbB-2 protein in gastric cancer. Its correlation with long-term survival of patients
-
Uchino S, Tsuda H, Maruyama K, et al. Overexpression of c-erbB-2 protein in gastric cancer. Its correlation with long-term survival of patients. Cancer 1993;72:3179-84
-
(1993)
Cancer
, vol.72
, pp. 3179-3184
-
-
Uchino, S.1
Tsuda, H.2
Maruyama, K.3
-
43
-
-
0027219281
-
Relationship of c-erbB-2 protein expression and gene amplification to invasion and metastasis in human gastric cancer
-
Mizutani T, Onda M, Tokunaga A, et al. Relationship of c-erbB-2 protein expression and gene amplification to invasion and metastasis in human gastric cancer. Cancer 1993;72:2083-8
-
(1993)
Cancer
, vol.72
, pp. 2083-2088
-
-
Mizutani, T.1
Onda, M.2
Tokunaga, A.3
-
44
-
-
0033135820
-
The prognostic significance of amplification and overexpression of c-met and c-erbB-2 in human gastric carcinomas
-
Nakajima M, Sawada H, Yamada Y, et al. The prognostic significance of amplification and overexpression of c-met and c-erbB-2 in human gastric carcinomas. Cancer 1999;85:1894-902
-
(1999)
Cancer
, vol.85
, pp. 1894-1902
-
-
Nakajima, M.1
Sawada, H.2
Yamada, Y.3
-
45
-
-
33748154637
-
HER-2/neu amplification is an independent prognostic factor in gastric cancer
-
Park DI, Yun JW, Park JH, et al. HER-2/neu amplification is an independent prognostic factor in gastric cancer. Dig Dis Sci 2006;51:1371-9
-
(2006)
Dig Dis Sci
, vol.51
, pp. 1371-1379
-
-
Park, D.I.1
Yun, J.W.2
Park, J.H.3
-
46
-
-
24344489058
-
Suppression of tumor growth in human gastric cancer with HER2 overexpression by an anti-HER2 antibody in a murine model
-
Matsui Y, Inomata M, Tojigamori M, et al. Suppression of tumor growth in human gastric cancer with HER2 overexpression by an anti-HER2 antibody in a murine model. Int J Oncol 2005;27:681-5
-
(2005)
Int J Oncol
, vol.27
, pp. 681-685
-
-
Matsui, Y.1
Inomata, M.2
Tojigamori, M.3
-
47
-
-
33947320114
-
Antitumor activity of trastuzumab in combination with chemotherapy in human gastric cancer xenograft models
-
Fujimoto-Ouchi K, Sekiguchi F, Yasuno H, et al. Antitumor activity of trastuzumab in combination with chemotherapy in human gastric cancer xenograft models. Cancer Chemother Pharmacol 2007;59:795-805
-
(2007)
Cancer Chemother Pharmacol
, vol.59
, pp. 795-805
-
-
Fujimoto-Ouchi, K.1
Sekiguchi, F.2
Yasuno, H.3
-
48
-
-
38749149510
-
Trastuzumab inhibits the growth of human gastric cancer cell lines with HER2 amplification synergistically with cisplatin
-
Kim SY, Kim HP, Kim YJ, et al. Trastuzumab inhibits the growth of human gastric cancer cell lines with HER2 amplification synergistically with cisplatin. Int J Oncol 2008;32:89-95
-
(2008)
Int J Oncol
, vol.32
, pp. 89-95
-
-
Kim, S.Y.1
Kim, H.P.2
Kim, Y.J.3
-
49
-
-
42449156456
-
Phase II of trastuzumab and cisplatin in patients with advanced gastric cancer with HER2/neu overexpression/amplification [abstract 4613]
-
Cortés-Funes H, Rivera F, Alés I, et al. Phase II of trastuzumab and cisplatin in patients with advanced gastric cancer with HER2/neu overexpression/amplification [abstract 4613]. J Clin Oncol 2007;15:18S
-
(2007)
J Clin Oncol
, vol.15
-
-
Cortés-Funes, H.1
Rivera, F.2
Alés, I.3
-
50
-
-
67650395446
-
Early results of a trial of trastuzumab, cisplatin and docetaxel for the treatment of metastatic gastric cancer overexpressing HER-2 [abstract 1105]
-
Nicholas G, Cripps C, Au H-P, et al. Early results of a trial of trastuzumab, cisplatin and docetaxel for the treatment of metastatic gastric cancer overexpressing HER-2 [abstract 1105]. ESMO 2006;17(Suppl 9):316
-
(2006)
ESMO
, vol.17
, Issue.SUPPL. 9
, pp. 316
-
-
Nicholas, G.1
Cripps, C.2
Au, H.-P.3
-
51
-
-
50849143901
-
A pilot study of trastuzumab monotherapy in patients who progressed while on chemotherapy for metastatic or locally advanced HER-2 positive gastric cancer [abstract 1096]
-
Rech J, Arnold D, Folprecht G, et al. A pilot study of trastuzumab monotherapy in patients who progressed while on chemotherapy for metastatic or locally advanced HER-2 positive gastric cancer [abstract 1096]. ESMO 2006;17(Suppl 9):314
-
(2006)
ESMO
, vol.17
, Issue.SUPPL. 9
, pp. 314
-
-
Rech, J.1
Arnold, D.2
Folprecht, G.3
-
52
-
-
55949117201
-
The growth inhibitory effect of lapatinib, a dual inhibitor of EGFR and HER2 tyrosine kinase, in gastric cancer cell lines
-
Kim JW, Kim HP, Im SA, et al. The growth inhibitory effect of lapatinib, a dual inhibitor of EGFR and HER2 tyrosine kinase, in gastric cancer cell lines. Cancer Lett 2008; 272(2):296-306
-
(2008)
Cancer Lett
, vol.272
, Issue.2
, pp. 296-306
-
-
Kim, J.W.1
Kim, H.P.2
Im, S.A.3
-
53
-
-
67650427284
-
S0413: A phase II SWOG study of GW572016 (lapatinib) as first line therapy in patients (pts) with advanced or metastatic gastric cancer
-
abstract 4621, 1, 5 June, Chicago, IL, USA
-
Iqbal S, Goldman B, Lenz HJ, et al. S0413: a phase II SWOG study of GW572016 (lapatinib) as first line therapy in patients (pts) with advanced or metastatic gastric cancer [abstract 4621]. Gastrointestinal (Noncolorectal) Cancer, 2007 ASCO Annual Meeting, 1 - 5 June, Chicago, IL, USA
-
Gastrointestinal (Noncolorectal) Cancer, 2007 ASCO Annual Meeting
-
-
Iqbal, S.1
Goldman, B.2
Lenz, H.J.3
-
54
-
-
85013312416
-
Tumor angiogenesis: Therapeutic implications
-
Folkman J. Tumor angiogenesis: therapeutic implications. N Engl J Med 1971;285:1182-6
-
(1971)
N Engl J Med
, vol.285
, pp. 1182-1186
-
-
Folkman, J.1
-
56
-
-
33947370773
-
Vascular endothelial growth factor (VEGF) signaling in tumor progression
-
Roskoski R. Vascular endothelial growth factor (VEGF) signaling in tumor progression. Crit Rev Oncol Hematol 2007;62:179-213
-
(2007)
Crit Rev Oncol Hematol
, vol.62
, pp. 179-213
-
-
Roskoski, R.1
-
57
-
-
0030066037
-
Prognostic value of vascular endothelial growth factor expression in gastric carcinoma
-
Maeda K, Chung YS, Ogawa S, et al. Prognostic value of vascular endothelial growth factor expression in gastric carcinoma. Cancer 1996;77;858-63
-
(1996)
Cancer
, vol.77
, pp. 858-863
-
-
Maeda, K.1
Chung, Y.S.2
Ogawa, S.3
-
58
-
-
0034729146
-
Plasma concentrations of VEGF and bFGF in patients with gastric carcinoma
-
Yoshikawa T, Tsuburaya A, Kobayashi O, et al. Plasma concentrations of VEGF and bFGF in patients with gastric carcinoma. Cancer Lett 2000;153:7-12
-
(2000)
Cancer Lett
, vol.153
, pp. 7-12
-
-
Yoshikawa, T.1
Tsuburaya, A.2
Kobayashi, O.3
-
59
-
-
33845490014
-
-
Sandler AB, Gray R, Brahmer A, et al. Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without bevacizumab (NSC #704865) in patients with advanced non-squamous non-small cell lung cancer (NSCLC): An Eastern Cooperative Oncology Group (ECOG) trial - E4599. N Engl J Med 2006;355:2542-50. Erratum in: N Engl J Med 2007;356:318
-
Sandler AB, Gray R, Brahmer A, et al. Randomized phase II/III trial of paclitaxel (P) plus carboplatin (C) with or without bevacizumab (NSC #704865) in patients with advanced non-squamous non-small cell lung cancer (NSCLC): An Eastern Cooperative Oncology Group (ECOG) trial - E4599. N Engl J Med 2006;355:2542-50. Erratum in: N Engl J Med 2007;356:318
-
-
-
-
60
-
-
37549040613
-
E2100: A randomized phase III trial of paclitaxel versus paclitaxel plus bevacizumab as first line therapy for locally recurrent or metastatic breast cancer
-
Miller KD, Wang M, Gralow J, et al. E2100: a randomized phase III trial of paclitaxel versus paclitaxel plus bevacizumab as first line therapy for locally recurrent or metastatic breast cancer. N Engl J Med 2007;357:2666-76
-
(2007)
N Engl J Med
, vol.357
, pp. 2666-2676
-
-
Miller, K.D.1
Wang, M.2
Gralow, J.3
-
61
-
-
2542561964
-
Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
-
Hurwitz H, Fehrenbacher L, Novotny W, et al. Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer. N Engl J Med 2004;350:2335-42
-
(2004)
N Engl J Med
, vol.350
, pp. 2335-2342
-
-
Hurwitz, H.1
Fehrenbacher, L.2
Novotny, W.3
-
62
-
-
42949149159
-
Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: A randomized phase III study
-
Saltz Clarke S, Diaz-Rubio E. Bevacizumab in combination with oxaliplatin-based chemotherapy as first-line therapy in metastatic colorectal cancer: a randomized phase III study. J Clin Oncol 2008;26;2013-19
-
(2008)
J Clin Oncol
, vol.26
, pp. 2013-2019
-
-
Saltz Clarke, S.1
Diaz-Rubio, E.2
-
63
-
-
0031870765
-
Anti-tumor and anti-metastatic effects of human vascular-endothelial-growth-factor-neutralizing antibody on human colon and gastric carcinoma xenotransplanted orthotopically into nude mice
-
Kanai T, Konno H, Tanaka T, et al. Anti-tumor and anti-metastatic effects of human vascular-endothelial-growth-factor-neutralizing antibody on human colon and gastric carcinoma xenotransplanted orthotopically into nude mice. Int J Cancer 1998;77:185-90
-
(1998)
Int J Cancer
, vol.77
, pp. 185-190
-
-
Kanai, T.1
Konno, H.2
Tanaka, T.3
-
64
-
-
17844373871
-
Thromboembolic events in gastric cancer: High incidence in patients receiving irinotecan and bevacizumab-based therapy
-
Shah MA, Ilson D, Kelsen DP. Thromboembolic events in gastric cancer: high incidence in patients receiving irinotecan and bevacizumab-based therapy. J Clin Oncol 2005;23:2574-6
-
(2005)
J Clin Oncol
, vol.23
, pp. 2574-2576
-
-
Shah, M.A.1
Ilson, D.2
Kelsen, D.P.3
-
65
-
-
33846629672
-
Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma
-
Shah MA, Ramanathan RK, Ilson DH, et al. Multicenter phase II study of irinotecan, cisplatin, and bevacizumab in patients with metastatic gastric or gastroesophageal junction adenocarcinoma. J Clin Oncol 2006;24:5201-6
-
(2006)
J Clin Oncol
, vol.24
, pp. 5201-5206
-
-
Shah, M.A.1
Ramanathan, R.K.2
Ilson, D.H.3
-
66
-
-
67650435951
-
A phase II study of bevacizumab, docetaxel and oxaliplatin in gastric and gastroesophageal junct (GEJ) cancer
-
abstract 15608, 30 May, 3 June, Chicago, IL, USA
-
El-rayes BF, Hammad N, Philip PA, et al. A phase II study of bevacizumab, docetaxel and oxaliplatin in gastric and gastroesophageal junct (GEJ) cancer [abstract 15608]. Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting, 30 May - 3 June, Chicago, IL, USA
-
Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting
-
-
El-rayes, B.F.1
Hammad, N.2
Philip, P.A.3
-
67
-
-
67650462131
-
A phase II study: Combination of sorafenib with docetaxel and cisplatin in the treatment of metastatic or advanced unresectable gastric and gastroesophageal junction (GEJ) adenocarcinoma (ECOG 5203)
-
abstract 4535, 30 May, 3 June, Chicago, IL, USA
-
Sun W, Powell ME, et al. A phase II study: combination of sorafenib with docetaxel and cisplatin in the treatment of metastatic or advanced unresectable gastric and gastroesophageal junction (GEJ) adenocarcinoma (ECOG 5203) [abstract 4535]. Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting, 30 May - 3 June, Chicago, IL, USA
-
Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting
-
-
Sun, W.1
Powell, M.E.2
-
68
-
-
67650395445
-
Sunitinib as second-line treatment for advanced gastric cancer: Preliminary results from a phase II study
-
abstract 4603, 1, 5 June, Chicago, IL, USA
-
Bang Y, Kang Y, Kang W, et al. Sunitinib as second-line treatment for advanced gastric cancer: preliminary results from a phase II study [abstract 4603]. Gastrointestinal (Noncolorectal) Cancer, 2007 ASCO Annual Meeting, 1 - 5 June, Chicago, IL, USA
-
Gastrointestinal (Noncolorectal) Cancer, 2007 ASCO Annual Meeting
-
-
Bang, Y.1
Kang, Y.2
Kang, W.3
-
69
-
-
0027384917
-
Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion
-
Davies B, Waxman J, Wasan H, et al. Levels of matrix metalloproteases in bladder cancer correlate with tumor grade and invasion. Cancer Res 1993;53:5365-9
-
(1993)
Cancer Res
, vol.53
, pp. 5365-5369
-
-
Davies, B.1
Waxman, J.2
Wasan, H.3
-
70
-
-
0028104790
-
Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line
-
Montgomery AM, Mueller BM, Reisfeld RA, et al. Effect of tissue inhibitor of the matrix metalloproteinases-2 expression on the growth and spontaneous metastasis of a human melanoma cell line. Cancer Res 1994;54:5467-73
-
(1994)
Cancer Res
, vol.54
, pp. 5467-5473
-
-
Montgomery, A.M.1
Mueller, B.M.2
Reisfeld, R.A.3
-
71
-
-
0035660661
-
Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma
-
Monig SP, Baldus SE, Hennecken JK, et al. Expression of MMP-2 is associated with progression and lymph node metastasis of gastric carcinoma. Histopathology 2001;39:597-602
-
(2001)
Histopathology
, vol.39
, pp. 597-602
-
-
Monig, S.P.1
Baldus, S.E.2
Hennecken, J.K.3
-
72
-
-
0029903248
-
Matrix metalloproteinases and tumor invasion: From correlation and causality to the clinic [Review]
-
Stetler-Stevenson WG, Hewitt R, Corcoran M. Matrix metalloproteinases and tumor invasion: from correlation and causality to the clinic [Review]. Semin Cancer Biol 1996;7:147-54
-
(1996)
Semin Cancer Biol
, vol.7
, pp. 147-154
-
-
Stetler-Stevenson, W.G.1
Hewitt, R.2
Corcoran, M.3
-
73
-
-
0036048505
-
Matrix metalloproteinase inhibitor, marimastat, decreases peritoneal spread of gastric carcinoma in nude mice
-
Kimata M, Otani Y, Kubota T, et al. Matrix metalloproteinase inhibitor, marimastat, decreases peritoneal spread of gastric carcinoma in nude mice. Jpn J Cancer Res 2002;93:834-1
-
(2002)
Jpn J Cancer Res
, vol.93
, pp. 834-841
-
-
Kimata, M.1
Otani, Y.2
Kubota, T.3
-
74
-
-
0032834472
-
Inhibition of tumour growth by marimastat in a human xenograft model of gastric cancer: Relationship with levels of circulating CEA
-
Watson SA, Morris TM, Collins HM, et al. Inhibition of tumour growth by marimastat in a human xenograft model of gastric cancer: relationship with levels of circulating CEA. Br J Cancer 1999;81:19-23
-
(1999)
Br J Cancer
, vol.81
, pp. 19-23
-
-
Watson, S.A.1
Morris, T.M.2
Collins, H.M.3
-
75
-
-
0033119677
-
A pilot study of the safety and effects of the matrix metalloproteinase inhibitor marimastat in gastric cancer
-
Tierney GM, Griffin NR, Stuart RC, et al. A pilot study of the safety and effects of the matrix metalloproteinase inhibitor marimastat in gastric cancer. Eur J Cancer 1999;35:563-8
-
(1999)
Eur J Cancer
, vol.35
, pp. 563-568
-
-
Tierney, G.M.1
Griffin, N.R.2
Stuart, R.C.3
-
76
-
-
3042802135
-
Marimastat as maintenance therapy for patients with advanced gastric cancer: A randomised trial
-
Bramhall SR, Hallissey MT, Whiting J, et al. Marimastat as maintenance therapy for patients with advanced gastric cancer: a randomised trial. Br J Cancer 2002;86:1864-70
-
(2002)
Br J Cancer
, vol.86
, pp. 1864-1870
-
-
Bramhall, S.R.1
Hallissey, M.T.2
Whiting, J.3
-
77
-
-
42649122953
-
Blocking on the CXCR4/mTOR signalling pathway induces the anti- metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells
-
Hashimoto I, Koizumi K, Tatematsu M, et al. Blocking on the CXCR4/mTOR signalling pathway induces the anti- metastatic properties and autophagic cell death in peritoneal disseminated gastric cancer cells. Eur J Cancer 2008;44:1022-9
-
(2008)
Eur J Cancer
, vol.44
, pp. 1022-1029
-
-
Hashimoto, I.1
Koizumi, K.2
Tatematsu, M.3
-
78
-
-
67650447849
-
Multicenter phase II study of RAD001 for previously treated metastatic gastric cancer (MGC): Preliminary results
-
abstract 4541, 30 May, 3 June, Chicago, IL, USA
-
Muro K, Boku N, Yamada Y, et al. Multicenter phase II study of RAD001 for previously treated metastatic gastric cancer (MGC): Preliminary results [abstract 4541]. Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting, 30 May - 3 June, Chicago, IL, USA
-
Gastrointestinal (Noncolorectal) Cancer, 2008 ASCO Annual Meeting
-
-
Muro, K.1
Boku, N.2
Yamada, Y.3
-
79
-
-
67650421674
-
Phase II trial of docetaxel, cisplatin, irinotecan, and bevacizumab in metastatic esophagogastric cancer
-
abstract 97, 27 January, Orlando, FL, USA
-
Enzinger PC, Ryan DP, Regan EM, et al. Phase II trial of docetaxel, cisplatin, irinotecan, and bevacizumab in metastatic esophagogastric cancer [abstract 97]. 2008 Gastrointestinal Cancers Symposium, ASCO 2008, 25 - 27 January, Orlando, FL, USA
-
2008 Gastrointestinal Cancers Symposium, ASCO 2008, 25
-
-
Enzinger, P.C.1
Ryan, D.P.2
Regan, E.M.3
-
80
-
-
67650450330
-
FOLFOX6 and bevacizumab (FOLFOX6/B) for metastatic esophageal (E), gastroesophageal (GE), and gastric (G) adenocarcinoma: A single institution's initial clinical experience
-
abstract 74, 27 January, Orlando, FL, USA
-
Cohenuram MK, Lacy J. FOLFOX6 and bevacizumab (FOLFOX6/B) for metastatic esophageal (E), gastroesophageal (GE), and gastric (G) adenocarcinoma: a single institution's initial clinical experience [abstract 74]. 2008 Gastrointestinal Cancers Symposium, ASCO 2008, 25 - 27 January, Orlando, FL, USA
-
2008 Gastrointestinal Cancers Symposium, ASCO 2008, 25
-
-
Cohenuram, M.K.1
Lacy, J.2
-
81
-
-
67650447850
-
A phase II study of bevacizumab, docetaxel, and oxaliplatin in gastric and gastroesophageal junction (GEJ) cancer
-
abstract 30, 27 January, Orlando, FL, USA
-
Hammad N, Philip PA, Shields AF, et al. A phase II study of bevacizumab, docetaxel, and oxaliplatin in gastric and gastroesophageal junction (GEJ) cancer [abstract 30]. 2008 Gastrointestinal Cancers Symposium, ASCO 2008, 25 - 27 January, Orlando, FL, USA
-
2008 Gastrointestinal Cancers Symposium, ASCO 2008, 25
-
-
Hammad, N.1
Philip, P.A.2
Shields, A.F.3
-
82
-
-
67650439090
-
Interim results of a phase II study of modified docetaxel, cisplatin, fluorouracil (mDCF), and bevacizumab (BEV) in patients with metastatic gastroesophageal (GE) adenocarcinoma
-
abstract 109, 27 January, Orlando, FL, USA
-
Jhawer MP, Ilson D, Robinson E, et al. Interim results of a phase II study of modified docetaxel, cisplatin, fluorouracil (mDCF), and bevacizumab (BEV) in patients with metastatic gastroesophageal (GE) adenocarcinoma [abstract 109]. 2008 Gastrointestinal Cancers Symposium, ASCO 2008, 25 - 27 January, Orlando, FL, USA
-
2008 Gastrointestinal Cancers Symposium, ASCO 2008, 25
-
-
Jhawer, M.P.1
Ilson, D.2
Robinson, E.3
|