Protected cyanohydrins in the synthesis of rotenoids: (±)- Munduserone and (±)-cis-12a-hydroxymunduserone

Journal of Organic Chemistry

Volumn 74, Issue 14, 2009, Pages 5097-5099

  Granados Covarrubias, Evin H ^a   Maldonado, Luis A ^a  

^a UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL EQUATIONS; COUPLING REACTION; NATURAL PRODUCTS; ROTENOIDS; SYNTHETIC ROUTES;

CHEMICAL REACTIONS;

CHEMICAL BONDS;

12A HYDROXYMUNDUSERONE; CYANOHYDRIN; FLAVONOID; LITHIUM; MUNDUSERONE; ROTENOID; UNCLASSIFIED DRUG;

ADDITION REACTION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CYCLIZATION; DEPROTECTION REACTION; DRUG STRUCTURE; DRUG SYNTHESIS; ISOMERIZATION; THIN LAYER CHROMATOGRAPHY;

MOLECULAR STRUCTURE; NITRILES; ROTENONE;

EID: 67650398310     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo900648n     Document Type: Article

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34. However, we are aware that the absence of 10 under inverse addition conditions is the main challenge of our view of the mechanism. See the Supporting Information for additional data on this issue.