Comparison of fused-core and conventional particle size columns by LC-MS/MS and UV: Application to pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis

Volumn 50, Issue 3, 2009, Pages 491-500

  Song, Wei ^a   Pabbisetty, Deepthi ^b   Groeber, Elizabeth A ^a   Steenwyk, Rick C ^a   Fast, Douglas M ^a  

^a PFIZER INC   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Desipramine; Fused core; Imipramine; LC MS MS; Pharmacokinetics; superficially porous; van Deemter

Indexed keywords

AMITRIPTYLINE; DESIPRAMINE; IMIPRAMINE; MORPHOLINE; TRIETHYLAMINE;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ISOLATION; DRUG STRUCTURE; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MALE; MATERIALS TESTING; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PARTICLE SIZE; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; SENSITIVITY AND SPECIFICITY; SIGNAL NOISE RATIO; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CHROMATOGRAPHY, LIQUID; DESIPRAMINE; IMIPRAMINE; MALE; RATS; RATS, SPRAGUE-DAWLEY; TANDEM MASS SPECTROMETRY; TIME FACTORS;

EID: 67650364379     PISSN: 07317085     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jpba.2009.05.011     Document Type: Article

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