Expression of I-CreI endonuclease generates deletions within the rDNA of Drosophila

Genetics

Volumn 181, Issue 4, 2009, Pages 1661-1671

  Paredes, Silvana ^a   Maggert, Keith A ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; I CREI PROTEIN; RIBOSOME DNA; UNCLASSIFIED DRUG; ENDODEOXYRIBONUCLEASE CREI; RESTRICTION ENDONUCLEASE;

ALLELE; ARTICLE; CHROMOSOME; CHROMOSOME DELETION; CHROMOSOME NOR; CONTROLLED STUDY; DNA DETERMINATION; DOUBLE STRANDED DNA BREAK; DROSOPHILA; FEMALE; MALE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RNA TRANSLATION; Y CHROMOSOME; ANIMAL; BIOLOGICAL MODEL; CHROMOSOME MAP; CROSS BREEDING; DNA MICROARRAY; GENE DELETION; GENE EXPRESSION REGULATION; GENETICS; PHYSIOLOGY;

ANIMALS; CHROMOSOME MAPPING; CROSSES, GENETIC; DNA RESTRICTION ENZYMES; DNA, RIBOSOMAL; DROSOPHILA; FEMALE; GENE DELETION; GENE EXPRESSION REGULATION, ENZYMOLOGIC; MALE; MODELS, BIOLOGICAL; MODELS, GENETIC; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS;

EID: 67650290212     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.108.099093     Document Type: Article

References (55)

1. ASHBURNER, M., K. G. GOLIC AND R. S. HAWLEY, 2005 Drosophila: A Laboratory Handbook, Ed. 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
2. AVERBECK, K. T., and T. H. EICKBUSH, 2005 Monitoring the mode and tempo of concerted evolution in the Drosophila melanogaster rDNA locus. Genetics 171: 1837-1846.
3. BRIDGES, C. B., 1916 Non-disjunction as proof of the chromosome theory of heredity. Genetics 1: 1-52.
4. CARMO-FONSECA, M., L. MENDES-SOARES AND I. CAMPOS, 2000 To be or not to be in the nucleolus. Nat. Cell Biol. 2: 107-112.
5. CLARK, A. G., F. M. SZUMSKI AND E. M. LYCKEGAARD, 1991 Population genetics of the Y chromosome of Drosophila melanogaster: rDNA variation and phenotypic correlates. Genet. Res. 58: 7-13.
6. COHEN, S., K. YACOBI AND D. SEGAL, 2003 Extrachromosomal circular DNA of tandemly repeated genomic sequences in Drosophila. Genome Res. 13: 1133-1145. (Pubitemid 36764193)
7. COHEN, S., N. AGMON, K. YACOBI, M. MISLOVATI AND D. SEGAL, 2005 Evidence for rolling circle replication of tandem genes in Drosophila. Nucleic Acids Res. 33: 4519-4526.
8. DE CICCO, D. V., AND D. M. GLOVER, 1983 Amplification of rDNA and type I sequences in Drosophila males deficient in rDNA. Cell 32: 1217-1225.
9. DOBIE, K. W., C. D. KENNEDY, V. M. VELASCO, T. L. MCGRATH, J. WEKO et al., 2001 Identification of chromosome inheritance modifiers in Drosophila melanogaster. Genetics 157: 1623-1637. (Pubitemid 32298831)
10. ENDOW, S. A., AND D. J. KOMMA, 1986 One-step and stepwise magnification of a bobbed lethal chromosome in Drosophila melanogaster. Genetics 114: 511-523.
11. FRENCH, S. L., Y. N. OSHEIM, F. CIOCI, M. NOMURA and A. L. BEYER, 2003 In exponentially growing Saccharomyces cerevisiae cells, rRNA synthesis is determined by the summed RNA polymerase I loading rate rather than by the number of active genes. Mol. Cell. Biol. 23: 1558-1568.
12. GERSH, E. S., 1968 Mutants at the bobbed locus in Drosophila melanogaster: Relation to ribosomalRNAsynthesis? Science 162: 1139.
13. GLOOR, G. B., C. R. PRESTON, D. M. JOHNSON-SCHLITZ, N. A. NASSIF, R. W. PHILLIS et al., 1993 Type I repressors of P element mobility. Genetics 125: 81-95.
14. GOLIC, K. G., and M. M. GOLIC, 1996 Engineering the Drosophila genome: chromosome rearrangements by design. Genetics 144: 1693-1711.
15. GOLIC, K. G., M. M. GOLIC and S. PIMPINELLI, 1998 Imprinted control of gene activity in Drosophila. Curr. Biol. 8: 1273-1276.
16. GOTTA, M., S. STRAHL-BOLSINGER, H. RENAULD, T. LAROCHE, B. K. KENNEDY et al., 1997 Localization of Sir2p: the nucleolus as a compartment for silent informationregulators.EMBOJ. 16: 3243-3255.
17. HAWLEY, R. S., and K. D. TARTOF, 1985 A two-stage model for the control of rDNA magnification. Genetics 109: 691-700. (Pubitemid 15148562)
18. JOHNSON, F. B., D. A. SINCLAIR AND L. GUARENTE, 1999 Molecular biology of aging. Cell 96: 291-302.
19. KOMMA, D. J., and S. A. ENDOW, 1986 Magnification of the ribosomal genes in female Drosophila melanogaster. Genetics 114: 859-874. (Pubitemid 17188106)
20. KOMMA, D. J., and S. A. ENDOW, 1987 Incomplete Y chromosomes promote magnification in male and female Drosophila. Proc. Natl. Acad. Sci. USA 84: 2382-2386.
21. bb- chromosome of Drosophila melanogaster. Genet. Res. 62: 205-212.
22. LEMOS, B., L. O. ARARIPE and D. L. HARTL, 2008 Polymorphic Y chromosomes harbor cryptic variation with manifold functional consequences. Science 319: 91-93.
23. LINDSLEY, D. L., and G. G. ZIMM, 1992 The Genome of Drosophila melanogaster. Academic Press, San Diego.
24. LONG, E., and I. B. DAWID, 1980 Repeated genes in eukaryotes. Annu. Rev. Biochem. 49: 727-764.
25. LYCKEGAARD, E. M., and A. G. CLARK, 1989 Ribosomal DNA and Stellate gene copy number variation on the Y chromosome of Drosophilamelanogaster. Proc.Natl.Acad. Sci.USA 86: 1944-1948.
26. MAGGERT, K. A., and K. G. GOLIC, 2005 Highly efficient sex chromosome interchanges produced by I-CreI expression in Drosophila. Genetics 171: 1103-1114.
27. MAGGERT, K. A., W. J. GONG and K. G. GOLIC, 2008 Methods for homologous recombination in Drosophila. Methods Mol. Biol. 420: 155-174.
28. MAILLET, L., C. BOSCHERON, M. GOTTA, S.MARCAND, E. GILSON et al., 1996 Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression. Genes Dev. 10: 1796-1811.
29. MARCUS, C. H., A. E. ZITRON, D. A. WRIGHT and R. S. HAWLEY, 1986 Autosomal modifiers of the bobbed phenotype are a major component of the rDNA magnification paradox in Drosophila melanogaster. Genetics 113: 305-319.
30. MARTINDILL, D. M., C. A. RISEBRO, N. SMART, M. FRANCO-VISERAS MDEL, C. O. Rosario et al., 2007 Nucleolar release of Hand1 acts as a molecular switch to determine cell fate. Nat. Cell Biol. 9: 1131-1141.
31. MAYER, C., K. M. SCHMITZ, J. LI, I. GRUMMT AND R. SANTORO, 2006 Intergenic transcripts regulate the epigenetic state of rRNA genes. Mol. Cell 22: 51-61.
32. MCSTAY, B., and I. GRUMMT, 2008 The epigenetics of rRNA genes: from molecular to chromosome biology. Annu. Rev. Cell Dev. Biol. 24: 131-157.
33. PALUMBO, G., M. BERLOCO, L. FANTI, M. P. BOZZETTI, S.MASSARI et al., 1994 Interaction systems between heterochromatin and euchromatin in Drosophila melanogaster. Genetica 94: 267-274.
34. PERRIN, L., O. DEMAKOVA, L. FANTI, S. KALLENBACH, S. SAINGERY et al., 1998 Dynamics of the sub-nuclear distribution of Modulo and the regulation of position-effect variegation by nucleolus in Drosophila. J. Cell Sci. 111: 2753-2761.
35. PROCUNIER, J. D., and K. D. TARTOF, 1978 A genetic locus having trans and contiguous cis functions that control the disproportionate replication of ribosomal RNA genes in Drosophila melanogaster. Genetics 88: 67-79.
36. RITOSSA, F. M., 1968 Unstable redundancy of genes for ribosomal RNA. Proc. Natl. Acad. Sci. USA 60: 509-516.
37. RITOSSA, F. M., and K. C. ATWOOD, 1996 Unequal proportions of DNA complementary to ribosomal RNA in males and females of Drosophila simulans. Proc. Natl. Acad. Sci. USA 56: 496-499.
38. ROBBINS, L., 1981 Genetically induced mitotic exchange in the heterochromatin of Drosophila melanogaster. Genetics 99: 443-459.
39. ROBBINS, L., 1996 Specificity of chromosome damage caused by the Rex element of Drosophila melanogaster. Genetics 144: 109-115.
40. SANDMEIER, J. J., S. FRENCH, Y. OSHEIM, W. L. CHEUNG, C. M. GALLO et al., 2002 RPD3 is required for the inactivation of yeast ribosomal DNA genes in stationary phase. EMBO J. 21: 4959-4968.
41. SCHATTNER, P., A. N. BROOKS AND T. M. LOWE, 2005 The tRNAscan-SE, snoscan and snoGPS web servers for the detection of tRNAs and snoRNAs. Nucleic Acids Res. 33: W686-W689.
42. SELIGMAN, L. M., K. M. STEPHENS, J. H. SAVAGE AND R. J. MONNAT, JR., 1997 Genetic analysis of the Chlamydomonas reinhardtii I-CreI mobile intron homing system in Escherichia coli. Genetics 147: 1653-1664.
43. SHERMOEN, A.W., and B. I. KIEFER, 1975 Regulation in rDNA-deficient Drosophila melanogaster. Cell 4: 275-280.
44. SPOFFORD, J. B., and R. DESALLE, 1991 Nucleolus organizer-suppressed position-effect variegation in Drosophila melanogaster. Genet. Res. 57: 245-255.
45. SULLIVAN, W., M. ASHBURNER and R. S.HAWLEy, 2000 Drosophila Protocols. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
46. TARTOF, K. D., 1973 Regulation of ribosomal RNA gene multiplicity in Drosophila melanogaster. Genetics 73: 57-71.
47. TARTOF, K. D., 1974 Unequal mitotic sister chromatin exchange as the mechanism of ribosomal RNA gene magnification. Proc. Natl. Acad. Sci. USA 71: 1272-1276.
48. TERRACOL, R., 1987 Differential magnification of rDNA gene types in bobbed mutants of Drosophila melanogaster. Mol. Gen. Genet. 208: 168-176.
49. TERRACOL, R., and N. PRUD'HOMME, 1981 26S and 18S rRNA synthesis in bobbed mutants of Drosophila melanogaster. Biochimie 63: 451-455.
50. TERRACOL, R., and N. PRUD'HOMME, 1986 Differential elimination of rDNA genes in bobbed mutants of Drosophila melanogaster. Mol. Cell. Biol. 6: 1023-1031.
51. TERRACOL, R., ITURBIDE, Y., and N. PRUD'HOMME, 1990 Partial reversion at the bobbed locus of Drosophila melanogaster. Biol. Cell 68: 65-71.
52. TAUTZ, D., J. M. HANCOCK, D. A. WEBB, C. TAUTZ and G. A. DOVER, 1988 Complete sequences of the rRNA genes of Drosophila melanogaster. Mol. Biol. Evol. 5: 366-376.
53. VERSA-OSTOJĆ, D., T. STANKOVIĆ, S. STEMBERGER-PAPIĆ, D. VRDOLJAK-MOZETIC, M. MANESTAR et al., 2008 Nuclear morphometry and AgNOR quantification: computerized image analysis on ovarian mucinous tumor imprints. Anal. Quant. Cytol. Histol. 3: 160-168.
54. WEBER, J. D, L. J. TAYLOR, M. F. ROUSSEL, C. J. SHERR and D. BAR-SAGI, 1999 Nucleolar Arf sequesters Mdm2 and activates p53. Nat. Cell Biol. 1: 20-26.
55. WELLAUER, P. K., and I. B. DAWID, 1977 The structural organization of ribosomal DNA in Drosophila melanogaster. Cell 10: 193-212. (Pubitemid 8056262)