Recovery of Skin Barrier Properties after Sonication in Human Subjects

Ultrasound in Medicine and Biology

Volumn 35, Issue 8, 2009, Pages 1405-1408

  Gupta, Jyoti ^a   Prausnitz, Mark R ^a  

^a Georgia Institute of Technology   (United States)

Author keywords

Electrical impedance; Skin permeability; Sonoporation; Transdermal drug delivery; Ultrasound

Indexed keywords

ELECTRICAL IMPEDANCE; SKIN PERMEABILITY; SONOPORATION; TRANSDERMAL DRUG DELIVERY; ULTRASOUND;

ACOUSTIC WAVES; ANESTHETICS; CAPILLARITY; ELECTRIC IMPEDANCE; ELECTRIC IMPEDANCE MEASUREMENT; METABOLISM; METABOLITES; SKIN; SONICATION; ULTRASONICS;

CONTROLLED DRUG DELIVERY;

ADULT; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; FEMALE; FOREARM; HUMAN; HUMAN EXPERIMENT; MALE; NORMAL HUMAN; PERMEABILITY BARRIER; PRIORITY JOURNAL; SKIN ABSORPTION; SKIN CONDUCTANCE; SKIN PERMEABILITY; ULTRASOUND;

ADMINISTRATION, CUTANEOUS; ADULT; ANESTHETICS, LOCAL; ELECTRIC IMPEDANCE; EQUIPMENT DESIGN; FEMALE; FOREARM; HUMANS; MALE; MIDDLE AGED; OCCLUSIVE DRESSINGS; SKIN; SKIN ABSORPTION; TIME FACTORS;

EID: 67650260349     PISSN: 03015629     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultrasmedbio.2009.04.001     Document Type: Article

References (12)

1. Farinha A., Kellogg S., Dickinson K., and Davidson T. Skin impedance reduction for electrophysiology measurements using ultrasonic skin permeation: Initial report and comparison to current methods. Biomed Instrum Technol 40 (2006) 72-77
2. Grubauer G., Elias P.M., and Feingold K.R. Transepidermal water loss: The signal for recovery of barrier structure and function. J Lipid Res 30 (1989) 323-333
3. Karande P., Jain A., and Mitragotri S. Relationships between skin's electrical impedance and permeability in the presence of chemical enhancers. J Control Release 110 (2005) 307-313
4. Katz N.P., Shapiro D.E., Herrmann T.E., Kost J., and Custer L.M. Rapid onset of cutaneous anesthesia with EMLA cream after pretreatment with a new ultrasound-emitting device. Anesth Analg 98 (2004) 371-376
5. Kost J., Mitragotri S., Gabbay R., Pishko M., and Langer R. Transdermal monitoring of glucose and other analytes using ultrasound. Nat Med 6 (2000) 347-350
6. Mitragotri S., and Kost J. Low-frequency sonophoresis: A review. Adv Drug Del Rev 56 (2004) 589-601
7. Park E.J., Werner J., and Smith N.B. Ultrasound mediated transdermal insulin delivery in pigs using a lightweight transducer. Pharm Res 24 (2007) 1396-1401
8. Prausnitz M.R., Mitragotri S., and Langer R. Current status and future potential of transdermal drug delivery. Nat Rev Drug Disc 3 (2004) 115-124
9. Tang H., Mitragotri S., Blankschtein D., and Langer R. Theoretical description of transdermal transport of hydrophilic permeants: Application to low-frequency sonophoresis. J Pharm Sci 90 (2001) 545-568
10. Tezel A., Sens A., and Mitragotri S. Description of transdermal transport of hydrophilic solutes during low-frequency sonophoresis based on a modified porous pathway model. J Pharm Sci 92 (2003) 381-393
11. Tezel A., Paliwal S., Shen Z., and Mitragotri S. Low-frequency ultrasound as a transcutaneous immunization adjuvant. Vaccine 23 (2005) 3800-3807
12. Wu J., Chappelow J., Yang J., and Weimann L. Defects generated in human stratum corneum specimens by ultrasound. Ultrasound Med Biol 24 (1998) 705-710