Transcriptional response of peripheral lymphocytes to early fibrosarcoma: A model system for cancer detection based on hybridization signatures

Experimental Biology and Medicine

Volumn 234, Issue 7, 2009, Pages 802-812

  Marques, Márcia M C ^a   Junta, Cristina M ^a   Zárate Blades, Carlos R ^a   Sakamoto Hojo, Elza Tiemi ^a   Donadi, Eduardo A ^a   Passos, Geraldo A S ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

cDNA microarray; Early cancer detection; Fibrosarcoma; Hybridization signatures; Immune surveillance; Lymphocyte gene profiling

Indexed keywords

CD19 ANTIBODY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; B LYMPHOCYTE; BAGG ALBINO MOUSE; CANCER CELL; CANCER DIAGNOSIS; CD3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL COUNT; CELL ISOLATION; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; FEMALE; FIBROSARCOMA; FLOW CYTOMETRY; GENE EXPRESSION; HYBRIDIZATION; IMMUNOCOMPETENCE; INJECTION; LYMPHOCYTE SUBPOPULATION; MALE; MICROARRAY ANALYSIS; MODEL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL LYMPHOCYTE;

ADENOSINE DEAMINASE; ANIMALS; ANTIGENS, CD19; B-LYMPHOCYTES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL LINE, TUMOR; CYCLIN-DEPENDENT KINASE 4; FEMALE; FIBROSARCOMA; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; HYBRIDIZATION, GENETIC; LYMPHOCYTES; MICE; MICE, INBRED BALB C; MODELS, BIOLOGICAL; POLY(ADP-RIBOSE) POLYMERASES; SENSITIVITY AND SPECIFICITY; TRANSCRIPTION, GENETIC;

ANIMALIA; MUS;

EID: 67650248705     PISSN: 15353702     EISSN: 15353699     Source Type: Journal    
DOI: 10.3181/0810-RM-311     Document Type: Article

References (19)

1. Staudt LM, Brown PO. Genomic view of the immune system. Ann Rev Immunol 18:829-859, 2000.
2. Shaffer AL, Rosenvald A, Hurt EM, Giltane JM, Lam LT, Pickreal OK, Staudt LM. Signatures of the immune response. Immunity 15:37-85, 2001.
3. Alizadeh A, Staudt LM. Genomic-scale gene expression profile of normal and malignant immune cells. Curr Opin Immunol 12:219-225, 2000.
4. Pardoll D. Does the immune system see tumors as foreign or self? Ann Rev Immunol 21:807-839, 2003.
5. Marques MM, Junta CM, Cardoso RS, Mello SS, Sakamoto-Hojo ET, Donadi EA, Passos GA. Changes in the gene expression profiling of the thymus in response to fibrosarcoma growth. Mol Cell Biochem 276:81-88, 2005.
6. Pereira E, Tamia-Ferreira MC, Cardoso RS, Mello SS, Sakamoto-Hojo, ET, Passos GA, Donadi EA. Immunosuppressive therapy modulates T lymphocyte gene expression in patients with systemic lupus erythematosus. Immunology 113:99-105, 2004.
7. + B cell gene products (ESTs) originated from systemic lupus erythematosus susceptibility loci. Autoimmun Rev 5:319-323, 2006.
8. Kovary K, Armelin MC, Armelin HA. Ha-Ras-1 oncogene dosage differentially effects BALB/3T3 cell's growth factor requirement and tumorigenicity. Oncogene Res 4:55-64, 1989.
9. Kovary K, Armelin MC, Armelin HA. Glucocorticoid dexamethazone reversibly complements RJ-Ras oncogene to transform mouse embryo BALB-3T3 cells. J Cell Biochem 41:171-177, 1989.
10. Tusher VG, Tibishirani R, Chu G. Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci U S A 98:5116-5121, 2001.
11. Zar JH. Biostatistical Analysis (4th ed.). New Jersey: Prentice Hall, 1999.
12. Hedge P, Qi K, Abernathy C, Gay S, Dharap R, Gaspard JE, Hughes E, Lee NS, Quackenbush JA. Concise guide to cDNA microarray analysis. BioTechniques 29:548-562, 2000.
13. Saeed AI, Sharov V, White J, Li J, Liang W, Bhagabati N, Braisted J, Klapa M, Currier T, Thiagarajan M, Sturn A, Snuffin M, Rezantsev A, Popov D, Ryltsov A, Kostukovich E, Borisovsky I, Liu Z, Vinsavich A, Trush V, Quackenbush J. TM4: a free, open-source system for microarray data management and analysis. BioTechniques 34:374-378, 2003.
14. Sharma P, Sahn NS, Tibishirani R, Skaane P, Urdal P, Berghagen H, Jensen M, Kristiansen L, Moen C, Sharma P, Zaka A, Arnes J, Sauer T, Akslen LA, Schlichting E, Børresen-Dale AL, Lönneborg A. Early detection of breast cancer based on gene-expression patterns in peripheral blood cells. Breast Cancer Res 7:R634-R644, 2005.
15. Bertucci F, Nasser V, Granjeaud S, Eisinger F, Adelaïde J, Tagett R, Loriod B, Giaconia A, Benziane A, Devilard E, Jacquemier J, Viens P, Nguyen C, Birnbaum D, Houlgatte R. Gene expression profiles of poor-prognosis primary breast cancer correlate with survival. Human Mol Genet 11:863-872, 2002.
16. Whitney AR, Diehn M, Popper SJ, Alizadeh AA, Boldrick JC, Relman DA, Brown PO. Individuality and variation in gene expression patterns in human blood. Proc Natl Acad Sci U S A 100:1896-1901, 2003.
17. Faca VM, Song KS, Wang H, Zhang Q, Krasnoselsky AL, Newcomb LF, Plentz RR, Gurumurthy S, Redston MS, Pitteri SJ, Pereira-Faca SR, Ireton RC, Katayama H, Glukhova V, Phanstiel D, Brenner DE, Anderson MA, Misek D, Scholler N, Urban ND, Barnett MJ, Edelstein C, Goodman GE, Thornquist MD, McIntosh MW, DePinho RA, Bardeesy N, Hanash SM. A mouse to human search for plasma proteome changes associated with pancreatic tumor development. PLoS Med 5:0953-0967, 2008.
18. Aldrich MB, Blackburn MR, Kellems RE. The importance of adenosine deaminase for lymphocyte development and function. Biochem Biophys Res Comm 272:311-315, 2000.
19. Tanaka T, Kohno H, Suzuki H,Yamada Y, Sugie S, Mori H. A novel inflammation-related mouse colon carcinogenesis model induced by azoxymethane and dextran sodium sulfate. Cancer Sci 94: 965-973, 2003.