Regulation of cellular contractile force in response to mechanical stretch by diphosphorylation of myosin regulatory light chain via RhoA signaling cascade

Cell Motility and the Cytoskeleton

Volumn 66, Issue 7, 2009, Pages 389-397

  Mizutani, Takeomi ^a   Kawabata, Kazushige ^a   Koyama, Yoshikazu ^b   Takahashi, Masayuki ^a   Haga, Hisashi ^a  

^a HOKKAIDO UNIVERSITY   (Japan)

^b HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Diphosphorylation; Mechanical stretch; Myosin regulatory light chain; RhoA; Scanning probe microscopy

Indexed keywords

MYOSIN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; FIBROBLAST; LIGHT CHAIN; MOUSE; MUSCLE CONTRACTILITY; MUSCLE STRETCHING; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN PHOSPHORYLATION; SCANNING PROBE MICROSCOPY; SIGNAL TRANSDUCTION; WESTERN BLOTTING; WILD TYPE;

ANIMALS; CELL LINE; FIBROBLASTS; MICE; MUSCLE CONTRACTION; MUTANT PROTEINS; MYOSIN LIGHT CHAINS; NIH 3T3 CELLS; PHOSPHORYLATION; RHO GTP-BINDING PROTEINS; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 67650165752     PISSN: 08861544     EISSN: 10970169     Source Type: Journal    
DOI: 10.1002/cm.20378     Document Type: Article

References (29)

1. Boudreault F, Grygorczyk R. 2002. Cell swelling-induced ATP release and gadolinium-sensitive channels. Am J Physiol Cell Physiol 282(1):C219-C226. (Pubitemid 34662569)
2. Brown RA, Prajapati R, McGrouther DA, Yannas IV, Eastwood M. 1998. Tensional homeostasis in dermal fibroblasts: Mechanical responses to mechanical loading in three-dimensional substrates. J Cell Physiol 175(3):323-332. (Pubitemid 28198212)
3. Daniel JL, Sellers JR. 1992. Purification and characterization of platelet myosin. Methods Enzymol 215:78-88.
4. Emmert DA, Fee JA, Goeckeler ZM, Grojean JM, Wakatsuki T, Elson EL, Herring BP, Gallagher PJ, Wysolmerski RB. 2004. Rhokinase-mediated Ca21-independent contraction in rat embryo fibroblasts. Am J Physiol Cell Physiol 286(1):C8-C21. (Pubitemid 38055808)
5. Giannone G, Sheetz MP. 2006. Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways. Trends Cell Biol 16(4):213-223.
6. Grinnell F. 2003. Fibroblast biology in three-dimensional collagen matrices. Trends Cell Biol 13(5):264-269. (Pubitemid 36556011)
7. Haga H, Sasaki S, Kawabata K, Ito E, Ushiki T, Sambongi T. 2000. Elasticity mapping of living fibroblasts by AFM and immuno-fluorescence observation of the cytoskeleton. Ultramicroscopy 82(1-4):253-258. (Pubitemid 30070109)
8. Hirata N, Takahashi M, Yazawa M. 2009. Diphosphorylation of regulatory light chain of myosin IIA is responsible for proper cell spreading. Biochem Biophys Res Commun 381:682-687.
9. Ikebe M, Hartshorne DJ, Elzinga M. 1986. Identification, phosphorylation, and dephosphorylation of a second site for myosin light chain kinase on the 20,000-dalton light chain of smooth muscle myosin. J Biol Chem 261(1):36-39. (Pubitemid 16144806)
10. Knoll R, Hoshijima M, Hoffman HM, Person V, Lorenzen-Schmidt I, Bang ML, Hayashi T, Shiga N, Yasukawa H, Schaper W, McKenna W, Yokoyama M, Schork NJ, Omens JH, McCulloch AD, Kimura A, Gregorio CC, Poller W, Schaper J, Schultheiss HP, Chien KR. 2002. The cardiac mechanical stretch sensor machinery involves a Z disc complex that is defective in a subset of human dilated cardiomyopathy. Cell 111(7):943-955. (Pubitemid 36044687)
11. Kolodney MS, Elson EL. 1993. Correlation of myosin light chain phosphorylation with isometric contraction of fibroblasts. J Biol Chem 268(32):23850-23855. (Pubitemid 23335357)
12. Makino A, Glogauer M, Bokoch GM, Chien S, Schmid-Schonbein GW. 2005. Control of neutrophil pseudopods by fluid shear: Role of Rho family GTPases. Am J Physiol Cell Physiol 288(4):C863-C871. (Pubitemid 40395064)
13. Mizutani T, Haga H, Kawabata K. 2004a. Cellular stiffness response to external deformation: Tensional homeostasis in a single fibroblast. Cell Motil Cytoskeleton 59(4):242-248. (Pubitemid 40012992)
14. Mizutani T, Haga H, Nemoto K, Kawabata K. 2004b. Wide-range scanning probe microscopy for visualizing biomaterials in the submillimeter range. Jpn J Appl Phys 43(7B):4525-4528.
15. Mizutani T, Haga H, Koyama Y, Takahashi M, Kawabata K. 2006. Diphosphorylation of the myosin regulatory light chain enhances the tension acting on stress fibers in fibroblasts. J Cell Physiol 209(3):726-731. (Pubitemid 44665694)
16. Murthy KS. 2006. Signaling for contraction and relaxation in smooth muscle of the gut. Annu Rev Physiol 68:345-374.
17. Naruse K, Yamada T, Sokabe M. 1998. Involvement of SA channels in orienting response of cultured endothelial cells to cyclic stretch. Am J Physiol 274(5 Pt 2):H1532-H1538. (Pubitemid 128733262)
18. Petroll WM, Vishwanath M, Ma L. 2004. Corneal fibroblasts respond rapidly to changes in local mechanical stress. Invest Ophthalmol Vis Sci 45(10):3466-3474. (Pubitemid 39298564)
19. Radmacher M, Fritz M, Kacher CM, Cleveland JP, Hansma PK. 1996. Measuring the viscoelastic properties of human platelets with the atomic force microscope. Biophys J 70(1):556-567. (Pubitemid 26021495)
20. Riento K, Ridley AJ. 2003. Rocks: Multifunctional kinases in cell behaviour. Nat Rev Mol Cell Biol 4(6):446-456. (Pubitemid 36648590)
21. Rosenblatt N, Hu S, Chen J, Wang N, Stamenovic D. 2004. Distending stress of the cytoskeleton is a key determinant of cell rheological behavior. Biochem Biophys Res Commun 321(3): 617-622. (Pubitemid 39118385)
22. 2+ waves are propagated via ATP release and purinergic receptor activation. Am J Physiol Cell Physiol 279(2): C295-C307.
23. Somlyo AP, Somlyo AV. 2003. Ca2+ sensitivity of smooth muscle and nonmuscle myosin II: Modulated by G proteins, kinases, and myosin phosphatase. Physiol Rev 83(4):1325-1358. (Pubitemid 37222274)
24. Tamada M, Sheetz MP, Sawada Y. 2004. Activation of a signaling cascade by cytoskeleton stretch. Dev Cell 7(5):709-718. (Pubitemid 39462691)
25. Trepat X, Grabulosa M, Puig F, Maksym GN, Navajas D, Farre R. 2004. Viscoelasticity of human alveolar epithelial cells subjected to stretch. Am J Physiol Lung Cell Mol Physiol 287(5):L1025-L1034. (Pubitemid 39391033)
26. Ueda K, Murata-Hori M, Tatsuka M, Hosoya H. 2002. Rho-kinase contributes to diphosphorylation of myosin II regulatory light chain in nonmuscle cells. Oncogene 21(38):5852-5860. (Pubitemid 35007235)
27. Wojciak-Stothard B, Ridley AJ. 2003. Shear stress-induced endothelial cell polarization is mediated by Rho and Rac but not Cdc42 or PI 3-kinases. J Cell Biol 161(2):429-439. (Pubitemid 36529859)
28. Yoshigi M, Hoffman LM, Jensen CC, Yost HJ, Beckerle MC. 2005. Mechanical force mobilizes zyxin from focal adhesions to actin filaments and regulates cytoskeletal reinforcement. J Cell Biol 171(2):209-215. (Pubitemid 41540014)
29. Yuasa HJ, Nakatomi A, Suzuki T, Yazawa M. 2002. Genomic structure of the sponge, Halichondria okadai calcyphosine gene. Gene 298(1):21-27. (Pubitemid 35284259)