Elevated erythropoietin in vitreous of patients with rhegmatogenous retinal detachment and proliferative vitreoretinopathy

Ophthalmic Research

Volumn 42, Issue 3, 2009, Pages 138-140

  Wang, Zhao Yang ^a,b   Shen, Li Jun ^b   Zhao, Ke Ke ^b   Song, Zong Ming ^b   Qu, Jia ^b  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b WENZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Erythropoietin; Proliferative vitreoretinopathy; Retinal detachment

Indexed keywords

ERYTHROPOIETIN;

ADULT; ARTICLE; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RETINA DETACHMENT; RETINA MACULA HOLE; VITREORETINOPATHY; VITREOUS BODY;

AGED; ENZYME-LINKED IMMUNOSORBENT ASSAY; ERYTHROPOIETIN; HUMANS; MIDDLE AGED; RETINAL DETACHMENT; RETINAL PERFORATIONS; VITREORETINOPATHY, PROLIFERATIVE; VITREOUS BODY;

EID: 67650115180     PISSN: 00303747     EISSN: None     Source Type: Journal    
DOI: 10.1159/000228592     Document Type: Article

References (17)

1. Pastor JC, de la Rúa ER, Martín F: Proliferative vitreoretinopathy: Risk factors and pathobiology. Prog Retin Eye Res 2002; 21: 127-144.
2. Harada C, Mitamura Y, Harada T: The role of cytokines and trophic factors in epiretinal membranes: involvement of signal transduction in glial cells. Prog Retin Eye Res 2006; 25 : 149-164.
3. Bartesaghi S, Marinovich M, Corsini E, Galli CL, Viviani B: Erythropoietin: a novel neuroprotective cytokine. Neurotoxicology 2005 ; 26: 923-928.
4. Hardee ME, Arcasoy MO, Blackwell KL, Kirkpatrick JP, Dewhirst MW: Erythropoietin biology in cancer. Clin Cancer Res 2006; 12 : 332-339.
5. Manzoni P, Maestri A, Gomirato G, Takagi H, Watanabe D, Matsui S: Erythropoietin as a retinal angiogenic factor. N Engl J Med 2005 ; 353: 2190-2191.
6. Inomata Y, Hirata A, Takahashi E, Kawaji T, Fukushima M, Tanihara H: Elevated erythropoietin in vitreous with ischemic retinal diseases. Neuroreport 2004; 15: 877-879.
7. Watanabe D, Suzuma K, Matsui S, Kurimoto M, Kiryu J, Kita M, Suzuma I, Ohashi H, Ojima T, Murakami T, Kobayashi T, Masuda S, Nagao M, Yoshimura N, Takagi H: Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy. N Engl J Med 2005 ; 353: 782-792. (Pubitemid 41215487)
8. Hernández C, Fonollosa A, García-Ramírez M, Higuera M, Catalán R, Miralles A, García-Arumí J, Simó R: Erythropoietin is expressed in the human retina and it is highly elevated in the vitreous fluid of patients with diabetic macular edema. Diabetes Care 2006 ; 29: 2028-2033.
9. Jonas JB, Neumaier M: Erythropoietin levels in aqueous humour in eyes with exudative age-related macular degeneration and diabetic retinopathy. Clin Experiment Ophthalmol 2007 ; 35: 186-187.
10. Cumurcu T, Bulut Y, Demir HD, Yenisehirli G: Aqueous humor erythropoietin levels in patients with primary open-angle glaucoma. J Glaucoma 2007; 16: 645-648.
11. Xie Z, Wu X, Qiu Q, Gong Y, Song Y, Gu Q, Li C: Expression pattern of erythropoietin and erythropoietin receptor in experimental model of retinal detachment. Curr Eye Res 2007 ; 32: 757-764.
12. Retina Society Terminology Committee: The classification of retinal detachment with proliferative vitreoretinopathy. Am J Ophthalmol 1983 ; 90: 121-125.
13. Junk AK, Mammis A, Savitz SI, Singh M, Roth S, Malhotra S, Rosenbaum PS, Cerami A, Brines M, Rosenbaum DM: Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury. Proc Natl Acad Sci USA 2002; 99: 10659-10664.
14. Fu QL, Wu W, Wang H, Li X, Lee VW, So KF: Up-regulated endogenous erythropoietin/ erythropoietin receptor system and exogenous erythropoietin rescue retinal ganglion cells after chronic ocular hypertension. Cell Mol Neurobiol 2008; 28: 317-329.
15. Asaria RH, Gregor ZJ: Simple retinal detachments: identifying the at-risk case. Eye 2002; 16 : 404-410.
16. Arcasoy MO: The non-haematopoietic biological effects of erythropoietin. Br J Haematol 2008 ; 141: 14-31.
17. Kase S, Saito W, Ohgami K, Yoshida K, Furudate N, Saito A, Yokoi M, Kase M, Ohno S: Expression of erythropoietin receptor in human epiretinal membrane of proliferative diabetic retinopathy. Br J Ophthalmol 2007; 91 : 1376-1378.