Aqueous humor erythropoietin levels in patients with primary open-angle glaucoma

Journal of Glaucoma

Volumn 16, Issue 8, 2007, Pages 645-648

  Cumurcu, Tongabay ^a   Bulut, Yunus ^a   Demir, Helin Deniz ^a   Yenisehirli, Gulgun ^a  

^a GAZIOSMANPASA UNIVERSITY   (Turkey)

Author keywords

Aqueous humor; Erythropoietin; Primary open angle glaucoma; Serum

Indexed keywords

ERYTHROPOIETIN;

AGED; ANTERIOR EYE SEGMENT; AQUEOUS HUMOR; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; EYE SURGERY; FEMALE; HUMAN; MALE; OPEN ANGLE GLAUCOMA; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; SENILE CATARACT;

AGED; AQUEOUS HUMOR; CASE-CONTROL STUDIES; CATARACT; ENZYME-LINKED IMMUNOSORBENT ASSAY; ERYTHROPOIETIN; FEMALE; GLAUCOMA, OPEN-ANGLE; HUMANS; MALE; MIDDLE AGED; OSMOLAR CONCENTRATION; PILOT PROJECTS; PROSPECTIVE STUDIES;

EID: 37349090689     PISSN: 10570829     EISSN: None     Source Type: Journal    
DOI: 10.1097/IJG.0b013e31804a5eb3     Document Type: Article

References (28)

1. Agar A, Yip SS, Hill MA, et al. Pressure related apoptosis in neuronal cell lines. J Neurosci Res. 2000;60:495-503.
2. Cioffi GA. Ischemic model of optic nerve injury. Trans Am Ophthalmol Soc. 2005;103:592-613.
3. Tezel G, Wax MB. Hypoxia-inducible factor 1 alpha in the glaucomatous retina and optic nerve head. Arch Ophthalmol. 2004;122:1348-1356.
4. Semenza GL, Wang GL. A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation. Moll Cell Biol. 1992;12:5447-5454.
5. 2- regulated gene expression. FASEB. 2002;16:1151-1162.
6. Arjamaa O, Nikinmaa M. Oxygen-dependent diseases in the retina: role of hypoxia-inducible factors. Exp Eye Res. 2006;83:473-483.
7. Silva M, Grillot D, Benito A, et al. Erythropoietin can promote erythroid progenitor survival by repressing apoptosis through Bcl-XL and Bcl-2. Blood. 1996;88:1576-1582.
8. Sakanaka M, Wen TC, Matsuda S, et al. In vivo evidence that erythropoietin protects neurons from ischemic damage. Proc Natl Acad Sci USA. 1998;95:4635-4640.
9. Kawakami M, Sekugichi S, Sato K, et al. Erythropoietin receptor-mediated inhibition of exocytotic glutamate release confers neuroprotection during chemical ischemia. J Biol Chem. 2001;276:39469-39475.
10. Hu DN, Ritch R, Liebmann J, et al. Vascular endothelial factor is increased in aqueous humor of glaucomatous eyes. J Glaucoma. 2002;11:406-410.
11. Funatsu H, Yamashita H, Noma H, et al. Aqueous humor levels of cytokines are related to vitreous levels and progression of diabetic retinopathy in diabetic patients. Graefe's Arch Clin Exp Ophthalmol. 2005;243:3-8.
12. Yokoi M, Yamagashi SI, Takeuchi M, et al. Elevations of AGE and vascular endothelial growth factor with decreased total antioxidant status in the vitreous fluid of diabetic patients with retinopathy. Br J Ophthalmol. 2005;89:673-675.
13. Watanabe D, Suzuna K, Matsui S, et al. Erythropoietin as a retinal angiogenic factor in proliferative diabetic retinopathy. N Eng J Med. 2005;353:782-792.
14. Lip PL, Chatterjee S, Caine GJ, et al. Plasma vascular endothelial growth factor, angiopoietin-2, and soluble angiopoietin receptor tie-2 in diabetic retinopathy: effects of laser photocoagulation and angiotensin receptor blockade. Br J Ophthalmol. 2004;88:1543-1546.
15. Auricchio A, Rivera VM, Clackson T, et al. Pharmacological regulation of protein expression from adeno-associated viral vectors in the eye. Mol Ther. 2002;6:238-242.
16. Junk AK, Mammis A, Savitz SI, et al. Erythropoietin administration protects retinal neurons from acute ischemia-reperfusion injury. Proc Natl Acad Sci USA. 2002;99:10659-10664.
17. Tsai JC, Wu L, Worgul B, et al. Intravitreal administration of erythropoietin and preservation of retinal ganglion cells in an experimental rat model of glaucoma. Curr Eye Res. 2005;30:1025-1031.
18. Hirooka K, Tokuda M, Miyamoto O, et al. The Ginkgo biloba extract (EGb 761) provides a neuroprotective effect on retinal ganglion cells in a rat model of chronic glaucoma. Curr Eye Res. 2004;28:153-157.
19. Dirnagl U, Simon RP, Hallenbeck JM. Ischemic tolerance and endogeneus neuroprotection. Trends Neurosci. 2003;26:248-254.
20. Ruscher K, Freyer D, Karsch M, et al. Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model. J Neurosci. 2002;22:10291-10301.
21. Sadamoto Y, Igase K, Sakanaka M, et al. Erythropoietin prevents place navigation disability and cortical infarction in rats with permanent occlusion of the middle cerebral artery. Biochem Biophys Res Commun. 1998;253:26-32.
22. Kilic U, Kilic E, Soliz J, et al. Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2. FASEB J. 2005;19:249-251.
23. Tanaka T, Matsumoto M, Inagi R, et al. Induction of protective genes by cobalt ameliorates tubulointerstitial injury in the progressive Thy 1 nephritis. Kidney Int. 2005;68:2714-2725.
24. Kuchle M, Nguyen NX, Hannappel E, et al. The blood-aqueous barrier in eyes with pseudoexfoliation syndrome. Ophthalmic Res. 1995;27:136-142.
25. Nguyen NX, Kuchle M, Naumann GO. Quantification of blood-aqueous barrier breakdown after phacoemulsification in Fuchs' heterochromic uveitis. Ophthalmologica. 2005;219:21-25.
26. Vesaluoma M, Mertaniemi P, Mannonen S, et al. Cellular and plasma fibronectin in the aqueous humour of primary open-angle glaucoma, exfoliative glaucoma and cataract patients. Eye. 1998;12:886-890.
27. Arcieri ES, Pierre Filho PT, Wakamatsu TH, et al. The effects of prostaglandin analogues on the blood aqueous barrier and corneal thickness of phakic patients with primary open-angle glaucoma and ocular hypertension. Eye. 2006;25. [Epub ahead of print].
28. Myake K, Ota I, Ibaraki N, et al. Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia. Arch Ophthalmol. 2001;119:387-394.