(-)Deprenyl-N-oxide, a (-)deprenyl metabolite, is cytoprotective after hypoxic injury in PC12 cells, or after transient brain ischemia in gerbils

Journal of the Neurological Sciences

Volumn 283, Issue 1-2, 2009, Pages 182-186

  Szilágyi, Géza ^a   Simon, László ^a   Wappler, Edina ^a   Magyar, Kálmán ^a   Nagy, Zoltán ^a  

^a SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

Apoptosis; Deprenyl; Deprenyl N oxide; Gerbil stroke model; Neuroprotection; PC 12

Indexed keywords

CASPASE 3; DEPRENYL N OXIDE; DRUG METABOLITE; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; SELEGILINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN HYPOXIA; BRAIN PROTECTION; CONCENTRATION RESPONSE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; GERBIL; HIPPOCAMPUS; LOW DRUG DOSE; MITOCHONDRIAL MEMBRANE POTENTIAL; NERVE CELL NECROSIS; NEUROPROTECTION; NONHUMAN; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; RAT; TRANSIENT ISCHEMIC ATTACK;

ANIMALS; APOPTOSIS; BRAIN ISCHEMIA; CAROTID ARTERY DISEASES; CELL DEATH; CELL HYPOXIA; GERBILLINAE; HIPPOCAMPUS; MITOCHONDRIAL MEMBRANES; NEURONS; NEUROPROTECTIVE AGENTS; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES; SELEGILINE; TIME FACTORS;

EID: 67650099187     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2009.02.368     Document Type: Article

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