Patient-controlled analgesia comparison of morphine to dexmedetomidine plus morphine in patients undergoing laminectomy

Neurosurgery Quarterly

Volumn 18, Issue 3, 2008, Pages 178-181

  Gunes, Yasemin ^a   Ozbek, Tevfik Hayri ^a   Gunduz, Hasan Murat ^a   Gedik, Yasa Erim ^a   Erman, Tahsin ^a   Ozcengiz, Dilek ^a  

^a CUKUROVA UNIVERSITY   (Turkey)

Author keywords

Dexmedetomidine; Laminectomy; Morphine; Patientcontrolled analgesia

Indexed keywords

DEXMEDETOMIDINE; MORPHINE; ONDANSETRON;

ADULT; ARTICLE; BOLUS INJECTION; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEMOGRAPHY; DOUBLE BLIND PROCEDURE; DRUG EFFICACY; FEMALE; HEMODYNAMICS; HUMAN; INFORMED CONSENT; LAMINECTOMY; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MEDICAL SOCIETY; NAUSEA; OUTCOME ASSESSMENT; PAIN ASSESSMENT; PATIENT CONTROLLED ANALGESIA; POSTOPERATIVE PAIN; PRIORITY JOURNAL; PROFESSIONAL STANDARD; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SEDATION;

EID: 67650091397     PISSN: 10506438     EISSN: None     Source Type: Journal    
DOI: 10.1097/WNQ.0b013e318182099d     Document Type: Article

References (21)

1. Bollish SJ, Collins CL, Kirking DM, et al. Efficacy of patient-controlled versus conventional analgesia for postoperative pain. Clin Pharm. 1985;4:48-52.
2. Graves DA, Batenhorst RL, Bennett RL, et al. Morphine requirements using patient controlled analgesia: influence of diurnal variation and morbid obesity. Clin Pharm. 1983;2:49-53.
3. White PF. The changing role of non-opioid analgesic techniques in the management of postoperative pain. Anesth Analg. 2005;101: S5-S22.
4. Elia N, Lysakowski C, Tramer MR. Does multimodal analgesia with acetaminophen, nonsteroidal antiinflammatory drugs, or selective cyclooxygenase-2 inhibitors and patient-controlled analgesia morphine offer advantages over morphine alone? Meta-analyses of randomized trials. Anesthesiology. 2005;103:1296-1304.
5. Adriaenssens G, Vermeyen K, Hoffmann V, et al. Postoperative analgesia with IV patient-controlled morphine: effect of adding ketamine. Br J Anaesth. 1999;83:393-396.
6. Overdyk FJ, Carter R, Maddox RR, et al. Continuous oximetry/ capnometry monitoring reveals frequent desaturation and bradypnea during patient-controlled analgesia. Anesth Analg. 2007;105: 412-418.
7. Khan ZP, Ferguson CN, Jones RM. Alpha-2 and imidazoline receptor agonists. Their pharmacology and therapeutic role. Anaesthesia. 1999;54:146-165.
8. Bhana N, Goa KL, McClellan KJ. Dexmedetomidine. Drugs. 2000;59:263-268.
9. Peden CJ, Cloote AH, Stratford N, et al. The effect of intravenous dexmedetomidine premedication on the dose requirement of propofol to induce loss of consciousness in patients receiving alfentanil. Anaesthesia. 2001;56:408-413.
10. Aantaa R, Jaakola ML, Kallio A, et al. Reduction of the minimum alveolar concentration of isoflurane by dexmedetomidine. Anesthesiology. 1997;86:1055-1060.
11. Aantaa R, Kanto J, Scheinin M, et al. Dexmedetomidine, an a2-adrenoceptor agonist, reduces anesthetic requirements for patients undergoing minor gynecologic surgery. Anesthesiology. 1990;73: 230-235.
12. Bulow NM, Barbosa NV, Rocha JB. Opioid consumption in total intravenous anesthesia is reduced with dexmedetomidine: a comparative study with remifentanil in gynecologic videolaparoscopic surgery. J Clin Anesth. 2007;19:280-285.
13. Aantaa R, Kanto J, Scheinin M, et al. Dexmedetomidine premedication for minor gynecologic surgery. Anesth Analg. 1990; 70:407-413.
14. Cortinez LI, Hsu YW, Sum-Ping ST, et al. Dexmedetomidine pharmacodynamics: part II: crossover comparison of the analgesic effect of dexmedetomidine and remifentanil in healthy volunteers. Anesthesiology. 2004;101:1077-1083.
15. Meert TF, De Kock M. Potentiation of the analgesic properties of fentanyl-like opioids with alpha 2-adrenoceptor agonists in rats. Anesthesiology. 1994;81:677-688.
16. Bloor BC, Ward DS, Belleville JP, et al. Effects of intravenous dexmedetomidine in humans. II. Hemodynamic changes. Anesthesiology. 1992;77:1134-1142.
17. Talke P, Lobo E, Brown R. Systemically administered alpha (2)-agonist-induced peripheral vasoconstriction in human. Anesthesiology. 2003;99:65-70.
18. Videira RL, Ferreira RM. Dexmedetomidine and asystole. Anesthesiology. 2004;101:1479.
19. Arain SR, Ruehlow RM, Uhrich TD, et al. The efficacy of dexmedetomidine versus morphine for postoperative analgesia after major inpatient surgery. Anesth Analg. 2004;98:153-158.
20. Arain SR, Ebert TJ. The efficacy, side effects and recovery characteristics of dexmedetomidine versus propofol when used for intraoperative sedation. Anesth Analg. 2002;95:461-466.
21. Taghinia AH, Shapiro FE, Slavin SA. Dexmedetomidine in aesthetic facial surgery: improving anesthetic safety and efficacy. Plast Reconstr Surg. 2008;121:269-276.