The ability of the quadruple test to predict adverse perinatal outcomes in a high-risk obstetric population

Journal of Medical Screening

Volumn 16, Issue 2, 2009, Pages 55-59

  Lao, Michael R ^a,d   Calhoun, Byron C ^a   Bracero, Luis A ^a   Wang, Ying ^b   Seybold, Dara J ^b   Broce, Mike ^b   Hatjis, Christos G ^c  

^a WEST VIRGINIA UNIVERSITY   (United States)

^b CHARLESTON AREA MEDICAL CENTER   (United States)

^c Northeast Ohio Medical University   (United States)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA FETOPROTEIN; BIOLOGICAL MARKER; CHORIONIC GONADOTROPIN; ESTRIOL; INHIBIN A;

ADOLESCENT; ADULT; ADVERSE OUTCOME; ARTICLE; CONTROLLED STUDY; DOWN SYNDROME; FEMALE; GESTATIONAL AGE; HIGH RISK PREGNANCY; HORMONE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; MATERNAL SERUM; OBSTETRIC CARE; OUTPATIENT DEPARTMENT; PREDICTION; PREGNANCY OUTCOME; PRENATAL CARE; RETROSPECTIVE STUDY; RISK ASSESSMENT; SCREENING TEST; SECOND TRIMESTER PREGNANCY; TERTIARY HEALTH CARE; UNITED STATES;

ADULT; ALPHA-FETOPROTEINS; CHORIONIC GONADOTROPIN; DOWN SYNDROME; ESTRADIOL; FEMALE; HUMANS; INHIBINS; OBSTETRICS; OUTCOME ASSESSMENT (HEALTH CARE); PREDICTIVE VALUE OF TESTS; PREGNANCY; PRENATAL DIAGNOSIS; RETROSPECTIVE STUDIES; RISK; ROC CURVE; SENSITIVITY AND SPECIFICITY;

EID: 67650085273     PISSN: 09691413     EISSN: 14755793     Source Type: Journal    
DOI: 10.1258/jms.2009.009017     Document Type: Article

References (17)

1. Lepage N, Chitayat D, Kingdom J, Huang T. Association between second-trimester isolated high maternal serum maternal serum human chorionic gonadotropin levels and obstetric complications in singleton and twin pregnancies. Am J Obstet Gynecol 2003;188:1354-1359 (Pubitemid 36589135)
2. Moawad AH, Goldenberg RL, Mercer B, et al. The Preterm Prediction Study: the value of serum alkaline phosphatase, alpha-fetoprotein, plasma corticotropin-releasing hormone, and other serum markers for the prediction of spontaneous preterm birth. Am J Obstet Gynecol 2002;186:990-996
3. Pergament E, Stein AK, Fiddler M, Cho NH, Kupferminc MJ. Adverse pregnancy outcome after a false-positive screen for Down syndrome using multiple markers. Obstet Gynecol 1995;86:255-258 (Pubitemid 27331510)
4. Huerta-Enochian G, Katz V, Erfurth S. The association of abnormal alpha-fetoprotein and adverse pregnancy outcome. Does increased fetal surveillance affect pregnancy outcome? Am J Obstet Gynecol 2001;184:1549-1553
5. Cuckle H, Sehmi I, Jones R. Maternal serum inhibin A can predict pre-eclampsia. Br J Obstet Gynaecol 1998;105:1101-1103 (Pubitemid 28461504)
6. Baschat AA, Harman CR, Farid G, Chodirker BN, Evans JA. Very low second-trimester maternal serum alpha-fetoprotein: Association with high birth weight. Obstet Gynecol 2002;99:531-536 (Pubitemid 34246283)
7. Ilagan JG, Stamilio DM, Ural SH, Macones GA, Odibo AO. Abnormal multiple marker screens are associated with adverse perinatal outcomes in cases of intrauterine growth restriction. Am J Obstet Gynecol 2004;191:1465-1469 (Pubitemid 39421615)
8. Odibo AO, Sehdev HM, Stamilio DM, Macones GA. Evaluating the threshold of abnormal second trimester multiple marker screening tests associated with intra-uterine growth restriction. Am J Perinatol 2006;23:363-367 (Pubitemid 44267094)
9. Dugoff L, Hobbins JC, Malone FD, et al. Quad screen as a predictor of adverse pregnancy outcome. Obstet Gynecol 2005;106:260-267 (Pubitemid 41023261)
10. Aquilina J, Thompson O, Thilaganathan B, Harrington K. Improved early prediction of pre-eclampsia by combining second-trimester maternal serum inhibin-A uterine artery Dopper. Ultrasound Obstet Gynecol 2001;17:477-484 (Pubitemid 32575095)
11. Wald NJ, Morris JK, Ibison J, Wu T, George LM. Screening in early pregnancy for pre-eclampsia using Down syndrome quadruple test markers. Prenat Diagn 2006;26:559-564 (Pubitemid 43989192)
12. Alexander GR, Himes JH, Kaufman RB, Mor J, Kogan M. A United States national reference for fetal growth. Obstet Gynecol 1996;87:163-168 (Pubitemid 26033124)
13. Akobeng AK. Understanding diagnostic tests 3: receiver operating characteristic curves. Acta Paediatr 2007;96:644-647 (Pubitemid 46653167)
14. Kelly MJ, Dunstan FD, Lloyd K, Fone DL. Evaluating cutpoints for the MHI-5 MCS using the GHQ-12: a comparison of five different methods. BMC Psychiatry 2008;8:10
15. Sayin NC, Canda MT, Ahmet N, Arda S, Sut N, Varol FG. The association of triple-marker test results with adverse pregnancy outcomes in low-risk pregnancies with healthy newborns. Arch Gynecol Obstet 2008;277:47-53 (Pubitemid 350160079)
16. Rudnicka AR, Wald NJ, Huttly W, Hackshaw AK. Influence of maternal smoking on the birth prevalence of Down syndrome and on second trimester screening performance. Prenat Diagn 2002;22:893-897 (Pubitemid 35175989)
17. Crossley JA, Aitken DA, Waugh SM, Kelly T, Connor JM. Maternal smoking: age distribution, levels of alpha-fetoprotein and human chorionic gonadotropin, and effect on detection of Down syndrome pregnancies in second trimester screening. Prenat Diagn 2002;22:247-255 (Pubitemid 34245843)