Enhancement of Ih, but not inhibition of IM, is a key mechanism underlying the PACAP-induced increase in excitability of guinea pig intrinsic cardiac neurons

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 297, Issue 1, 2009, Pages

  Tompkins, John D ^a   Lawrence, Yancey T ^a   Parsons, Rodney L ^a  

^a UNIVERSITY OF VERMONT   (United States)

Author keywords

Hyperpolarization activated nonselective cation current; Neuronal excitability; Neuropeptide; Parasympathetic neurons

Indexed keywords

4 (N ETHYL N PHENYLAMINO) 1,2 DIMETHYL 6 (METHYLAMINO)PYRIMIDINIUM CHLORIDE; BARIUM; CESIUM CHLORIDE; HYPOPHYSIS ADENYLATE CYCLASE ACTIVATING POLYPEPTIDE; BARIUM CHLORIDE; BARIUM DERIVATIVE; CESIUM; CHLORIDE; CYCLIC NUCLEOTIDE GATED CHANNEL; ICI D2788; POTASSIUM; POTASSIUM CHANNEL; PYRIMIDINE DERIVATIVE;

ACTION POTENTIAL; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEPOLARIZATION; FEMALE; GUINEA PIG; HYPERPOLARIZATION; MALE; NERVE EXCITABILITY; NONHUMAN; POTASSIUM CONDUCTANCE; POTASSIUM CURRENT; PRIORITY JOURNAL; ANIMAL; COMPARATIVE STUDY; DRUG EFFECT; ELECTROSTIMULATION; HEART; IN VITRO STUDY; INNERVATION; METABOLISM; NERVE CELL; TIME;

ACTION POTENTIALS; ANIMALS; BARIUM COMPOUNDS; CESIUM; CHLORIDES; CYCLIC NUCLEOTIDE-GATED CATION CHANNELS; ELECTRIC STIMULATION; FEMALE; GUINEA PIGS; HEART; MALE; NEURONS; PITUITARY ADENYLATE CYCLASE-ACTIVATING POLYPEPTIDE; POTASSIUM; POTASSIUM CHANNELS; PYRIMIDINES; TIME FACTORS;

EID: 67650079655     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00039.2009     Document Type: Article

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