Signals in human breath related to Sarcoidosis. - Results of a feasibility study using MCC/IMS

International Journal for Ion Mobility Spectrometry

Volumn 12, Issue 2, 2009, Pages 73-79

  Bunkowski, A ^a   Bodeker B ^a,b   Bader, S ^a,c   Westhoff, M ^d   Litterst, P ^d   Baumbach, J I ^a  

^a LEIBNIZ INSTITUT FÜR ANALYTISCHE WISSENSCHAFTEN ISAS E V   (Germany)

^b TU DORTMUND UNIVERSITY   (Germany)

^c ROCHE DIAGNOSTICS GMBH   (Germany)

^d Lung Hospital Hemer   (Germany)

Author keywords

Human breath; IMS chromatogram; MCC IMS; Sarcoidosis; VOC

Indexed keywords

HUMAN BREATH; IMS-CHROMATOGRAM; MCC/IMS; SARCOIDOSIS; VOC;

INSULATING MATERIALS; PLANNING; RESOURCE ALLOCATION; VOLATILE ORGANIC COMPOUNDS;

TUMORS;

EID: 67650021747     PISSN: 14356163     EISSN: 18654584     Source Type: Journal    
DOI: 10.1007/s12127-009-0022-0     Document Type: Article

References (34)

1. A Amann A Schmid S Scholl-Buergi S Telser H Hinterhuber 2005 Breath analysis for medical diagnosis and therapeutic monitoring Spectrosc Eur 17 18 20 (Pubitemid 40952386)
2. P Spanel K Dryahina D Smith 2007 The concentration distributions of some metabolites in the exhaled breath of young adults J Breath Res 1 1 8
3. CH Patterson 2007 Dynamic study of oxidative stress in renal dialysis patients based on breath ethane measured by optical spectroscopy J Breath Res 1 1 8
4. D Smith C Turner P Spanel 2007 Volatile metabolites in the exhaled breath of healthy volunteers: their levels and distributions J Breath Res 1 R1 R12
5. P Spanel K Dryahina D Smith 2007 Acetone, ammonia and hydrogen cyanide in exhaled breath of several volunteers aged 4-83 years J Breath Res 1 L1 L4
6. JI Baumbach M Westhoff 2006 Ion mobility spectrometry to detect lung cancer and airway infections Spectrosc Eur 18 22 27 (Pubitemid 46133027)
7. JI Baumbach 2006 Process analysis using ion mobility spectrometry Anal Bioanal Chem 384 1059 1070 (Pubitemid 43333987)
8. M Westhoff 2006 Ionenmobilitätsspektrometrie-eine neue Methode zur Detektion von Bronchialkarzinomen und Atemwegsinfektionen in der Ausatemluft? Erste Resultate einer Pilotstudie Pneumologie 60 S81
9. M Westhoff 2005 Ion mobility spectrometry: A new method for the detection of lung cancer and airway infection in exhaled air? First results of a pilot study Chest 128 155S
10. PLM Westhoff L Freitag V Ruzsanyi JI Baumbach 2005 Bacterial differentiation by ion mobility spectrometry: First results of a pilot study Chest 128 375S 375S
11. V Ruzsanyi 2005 Detection of human metabolites using multi-capillary columns coupled to ion mobility spectrometers J Chromatogr A 1084 145 151 (Pubitemid 40966921)
12. Baumbach JI, Vautz W, Ruzsanyi V, Freitag L (2005) In: Anmann A, Smith D (eds) Breath analysis for clinical diagnosis and therapeutic monitoring. World Scientific, Singapore, pp 53-66
13. Baumbach JI, Vautz W, Ruzsanyi V, Freitag L (2005) In: Knäblein J (ed) Modern biopharmaceuticals, vol. 3. Wiley-VCH, Weinheim, pp 1343-1358
14. S Bader W Urfer J Baumbach 2005 Processing ion mobility spectrometry data to characterize group differences in a multiple class comparison Int J Ion Mobility Spectrom 8 1 4
15. S Bader W Urfer JI Baumbach 2007 Reduction of ion mobility spectrometry data by clustering characteristic peak structures J Chemom 20 128 135
16. J Baumbach 2007 IMS2-An integrated medical software system for early lung cancer detection using ion mobility spectrometry data of human breath J Integr Bioinformatics 4 75 71 12
17. M Westhoff 2006 Ion mobility spectrometry-a new method in the diagnostic approach to sarcoidosis? - Preliminary data Eur Respir J 28 111S
18. M Westhoff P Litterst L Freitag JI Baumbach 2007 Ion mobility spectrometry in the diagnosis of Sarcoidosis: results of a feasibility study J Physiol Pharmacol 58 739 751 (Pubitemid 351346724)
19. YP Moodley R Chetty UG Lalloo 1999 Nitric oxide levels in exhaled air and inducible nitric oxide synthase immunolocalization in pulmonary sarcoidosis Eur Respir J 14 822 827 (Pubitemid 29519344)
20. DM O'Donnell 1997 Exhaled nitric oxide and bronchoalveolar lavage nitrite/nitrate in active pulmonary sarcoidosis Am J Respir Crit Care Med. 156 1892 1896 (Pubitemid 28011798)
21. ML Wilsher W Fergusson D Milne AU Wells 2005 Exhaled nitric oxide in sarcoidosis Thorax 60 967 970 (Pubitemid 41598214)
22. D Ziora K Kaluska J Kozielski 2004 An increase in exhaled nitric oxide is not associated with activity in pulmonary sarcoidosis Eur Respir J 24 609 614 (Pubitemid 39406134)
23. D Ziora A Polonska K Kaluska P Rozentryt P Trzeciak 2002 Concentration of nitric oxide in exhaled air in patients with sarcoidosis-pilot study Pneumonol Alergol Pol 70 290 295
24. S Kwiatkowska M Luczynska I Grzelewska-Rzymowska D Nowak M Zieba 2005 Comparison of oxidative stress markers in exhaled breath condensate and in serum of patients with tuberculosis and sarcoidosis Pol Merkuriusz Lek 19 37 40 (Pubitemid 40992697)
25. K Psathakis 2004 8-Isoprostane, a marker of oxidative stress, is increased in the expired breath condensate of patients with pulmonary sarcoidosis Chest 125 1005 1011 (Pubitemid 38367293)
26. JI Baumbach GA Eiceman 1999 Ion mobility spectrometry: arriving on site and moving beyond a low profile Appl Spectrosc 53 338A 355A (Pubitemid 32078045)
27. Baumbach JI (2009) Ion mobility spectrometry coupled with multi-capillary columns for metabolic profiling of human breath. Journal of Breath Research
28. Ruzsanyi V (2005) Analyse flüchtiger Metaboliten von der Ausatemluft mittels Ionenmobilitätsspektrometer,Thesis Bio- und Chemieingenieurwesen (University Dortmund)
29. Bader S (2008) Identification and quantification of peaks in spectrometric data faculty statistics, (Technical University of Dortmund)
30. B Bödeker W Vautz JI Baumbach 2008 Visualisation of MCC/IMS-Data Int J Ion Mobility Spectrom 11 77 82
31. B Bödeker W Vautz JI Baumbach 2008 Peak Comparison in MCC/IMS-Data-Searching for potential biomarkers in human breath data Int J Ion Mobility Spectrom 11 89 93
32. B Bödeker W Vautz JI Baumbach 2008 Peak finding and referencing in MCC/IMS-data Int J Ion Mobility Spectrom 11 83 88
33. H Borsdorf GA Eiceman 2006 Ion mobility spectrometry: principles and applications Appl Spectrosc Rev 41 323 375 (Pubitemid 43922086)
34. Eiceman GA, Karpas Z (2005) Ion mobility spectrometry, vol. 1, edn. 1. CRC Press, Taylor & Francis, Boca Raton