Potential of adsorption isotherm measurements for closer elucidating of binding in chiral liquid chromatographic phase systems

Journal of Separation Science

Volumn 32, Issue 10, 2009, Pages 1491-1506

  Samuelsson, Jörgen ^a   Arnell, Robert ^b   Fornstedt, Torgny ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Adsorption energy distribution; Adsorption isotherms; Chiral LC; Enantioselectivity; Retention mechanism

Indexed keywords

ADSORPTION ENERGY DISTRIBUTION; ADSORPTION PROCESS; ANALYTICAL LABORATORIES; CHIRAL ENVIRONMENT; CHIRAL LC; CHIRAL PHASE; CHROMATOGRAPHIC PROCESS; ENANTIOSELECTIVE; EQUILIBRIUM DISTRIBUTIONS; HUMAN BODIES; ISOTHERM MEASUREMENT; PHASE SYSTEMS; PREPARATIVE SEPARATION; RETENTION MECHANISM; SELECTIVE BINDING; SEPARATION SYSTEMS; STATIONARY PHASIS;

ADSORPTION ISOTHERMS; ATMOSPHERIC TEMPERATURE; BINDING ENERGY; CHIRALITY; CHROMATOGRAPHIC ANALYSIS; DRUG INTERACTIONS; ELECTRIC POWER DISTRIBUTION; ELECTRON TRANSITIONS; ENANTIOMERS; ENANTIOSELECTIVITY; INTERFACIAL ENERGY; ION BEAMS; LABORATORIES; LIQUID CHROMATOGRAPHY;

ADSORPTION;

ACCURACY; ADSORPTION CHROMATOGRAPHY; CHEMICAL ANALYSIS; CHEMICAL BINDING; CHEMICAL COMPOSITION; CHIRAL CHROMATOGRAPHY; COLORIMETRY; COLUMN CHROMATOGRAPHY; DESORPTION; ENANTIOMER; ENANTIOSELECTIVITY; FRACTIONATION; ION PAIR CHROMATOGRAPHY; ISOTHERM; LIQUID CHROMATOGRAPHY; METHODOLOGY; PHASE SEPARATION; PRIORITY JOURNAL; PROCESS MODEL; PROCESS TECHNOLOGY; PROTEIN ANALYSIS; PROTEIN INTERACTION; PURIFICATION; REVIEW; THERMODYNAMICS;

ADSORPTION; ANIMALS; CHROMATOGRAPHY, LIQUID; HUMANS; MODELS, CHEMICAL; PROTEINS; REPRODUCIBILITY OF RESULTS; STEREOISOMERISM;

EID: 67650001350     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.200900165     Document Type: Review

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