Diffusion-Driven Device for a High-Resolution Dose-Response Profiling of Combination Chemotherapy

Analytical Chemistry

Volumn 81, Issue 13, 2009, Pages 5233-5240

  Ganser, Alexander ^a,b   Roth, Günter ^c,d   Van Galen, Joost C ^e   Hilderink, Janneke ^a   Wammes, Joost J G ^a   Müller, Ingo ^f   Van Leeuwen, Frank N ^e   Wiesmüller, Karl Heinz ^b   Brock, Roland ^a,c  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b EMC MICROCOLLECTIONS GMBH   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

^d UNIVERSITY OF FREIBURG   (Germany)

^e RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^f UNIVERSITY HOSPITAL TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

96-WELL FORMAT; ANNEXIN; BINDING ASSAYS; COMBINATION CHEMOTHERAPY; COMBINATION THERAPY; DOSE RESPONSE; DRUG COMBINATIONS; HIGH RESOLUTION; LEUKEMIA CELLS; MICROTITER PLATES; PARALLEL SCREENING; PERSONALIZED MEDICINES; PROCESSING STEPS; SMALL SAMPLES;

CELL CULTURE; CELL DEATH; CHEMOTHERAPY; MINIATURE INSTRUMENTS;

DIFFUSION;

CLOFARABINE; DOXORUBICIN; LIPOCORTIN 5;

ARTICLE; BINDING ASSAY; CELL ASSAY; CELL DEATH; CELL VIABILITY; COMBINATION CHEMOTHERAPY; COMPUTER AIDED DESIGN; CONTROLLED STUDY; DEVICE; DIFFUSION; DIFFUSION COEFFICIENT; ELECTRONICS; FLUORESCENCE; FLUORESCENCE MICROSCOPY; HUMAN; HUMAN CELL; LEUKEMIA CELL LINE; MICROTITER PLATE ASSAY; PROCESSING; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS;

ADENINE NUCLEOTIDES; ANNEXIN A5; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; ARABINONUCLEOSIDES; CELL DEATH; DIFFUSION; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG THERAPY, COMBINATION; FLUORESCENT DYES; HUMANS; MINIATURIZATION; PHOSPHATIDYLSERINES; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; TOXICITY TESTS; TUMOR CELLS, CULTURED;

EID: 67649980001     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac900415s     Document Type: Article

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