Diagnostic value of serum prolidase enzyme activity to predict the liver histological lesions in non-alcoholic fatty liver disease: A surrogate marker to distinguish steatohepatitis from simple steatosis

Digestive Diseases and Sciences

Volumn 54, Issue 8, 2009, Pages 1764-1771

  Kayadibi, Huseyin ^a   Gültepe, Mustafa ^b   Yasar, Bulent ^b   Ince, Ali T ^b   Ozcan, Omer ^b   Ipcioglu, Osman M ^b   Kurdas, Oya O ^b   Bolat, Burhanettin ^c   Benek, Yusuf Z ^b   Guveli, Hakan ^b   Atalay, Sacide ^b   Ozkara, Selvinaz ^b   Keskin, Ozcan ^a  

^a Ardahan Military Hospital Turkey   (Turkey)

^b GATA HAYDARPASA TRAINING HOSPITAL   (Turkey)

^c Tekirdag   (Turkey)

Author keywords

Biopsy; Fatty liver; Fibrosis; Inflammation; Prolidase

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; BIOCHEMICAL MARKER; PROLINE DIPEPTIDASE; BIOLOGICAL MARKER; DIPEPTIDASE;

ADULT; ALANINE AMINOTRANSFERASE BLOOD LEVEL; ALCOHOL LIVER DISEASE; ALCOHOLIC FATTY LIVER; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CLINICAL EVALUATION; COMPARATIVE STUDY; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DISEASE COURSE; ENZYME ACTIVITY; FEMALE; HEPATITIS; HISTOPATHOLOGY; HUMAN; INFLAMMATION; LIVER BIOPSY; LIVER FIBROSIS; MAJOR CLINICAL STUDY; MALE; NON ALCOHOLIC FATTY LIVER DISEASE; PREDICTOR VARIABLE; PRIORITY JOURNAL; STEATOHEPATITIS; STEATOSIS; BIOPSY; BLOOD; CASE CONTROL STUDY; DIFFERENTIAL DIAGNOSIS; ENZYMOLOGY; FATTY LIVER; LIVER; METABOLISM; MIDDLE AGED; MULTIVARIATE ANALYSIS; PATHOLOGY; PREDICTION AND FORECASTING; STATISTICAL MODEL;

ADULT; ALANINE TRANSAMINASE; ASPARTATE AMINOTRANSFERASES; BIOLOGICAL MARKERS; BIOPSY; CASE-CONTROL STUDIES; DIAGNOSIS, DIFFERENTIAL; DIPEPTIDASES; FATTY LIVER; FEMALE; HEPATITIS; HUMANS; LINEAR MODELS; LIVER; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PREDICTIVE VALUE OF TESTS;

EID: 67649973321     PISSN: 01632116     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10620-008-0535-0     Document Type: Article

References (24)

1. M Raman J Allard 2006 Non alcoholic fatty liver disease: a clinical approach and review Can J Gastroenterol 20 345 349 (Pubitemid 43918684)
2. K Te Sligte I Bourass JP Sels A Driessen RW Stockbrugger GH Koek 2004 Non-alcoholic steatohepatitis: review of a growing medical problem Eur J Intern Med 15 10 21 10.1016/j.ejim.2003.12.008
3. JA Marrero RJ Fontana GL Su HS Conjeevaram DM Emick AS Lok 2002 NAFLD may be a common underlying liver disease in patients with hepatocellular carcinoma in the United States Hepatology 36 1349 1354 (Pubitemid 35403524)
4. P Angulo JC Keach KP Batts KD Lindor 1999 Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis Hepatology 30 1356 1362 10.1002/hep.510300604
5. P Mishra ZM Younossi 2007 Abdominal ultrasound for diagnosis of nonalcoholic fatty liver disease (NAFLD) Am J Gastroenterol 102 2716 2717 10.1111/j.1572-0241.2007.01520.x
6. AJ Sanyal American Gastroenterological Association 2002 AGA technical review on nonalcoholic fatty liver disease Gastroenterology 123 1705 1725 10.1053/gast.2002.36572 (Pubitemid 35231670)
7. EM Brunt 2004 Nonalcoholic steatohepatitis Semin Liver Dis 24 3 20 (Pubitemid 38496045)
8. A Wieckowska AJ McCullough AE Feldstein 2007 Noninvasive diagnosis and monitoring of nonalcoholic steatohepatitis: present and future Hepatology 46 582 589 10.1002/hep.21768
9. T Poynard M Munteanu F Imbert-Bismut F Charlotte D Thabut S Le Calvez 2004 Prospective analysis of discordant results between biochemical markers and biopsy in patients with chronic hepatitis C Clin Chem 50 1344 1355 10.1373/clinchem.2004.032227
10. C Fabris C Smirne P Toniutto C Colletta R Rapetti R Minisini 2006 Assessment of liver fibrosis progression in patients with chronic hepatitis C and normal alanine aminotransferase values: the role of AST to the platelet ratio index Clin Biochem 39 339 343 10.1016/j.clinbiochem.2006.01.011
11. BT Kurien NC Patel AC Porter A D'Souza D Miller H Matsumoto 2006 Prolidase deficiency and the biochemical assays used in its diagnosis Anal Biochem 349 165 175 10.1016/j.ab.2005.10.018
12. I Myara A Myara M Mangeot M Fabre C Charpentier A Lemonnier 1984 Plasma prolidase activity: a possible index of collagen catabolism in chronic liver disease Clin Chem 30 211 215 (Pubitemid 14190267)
13. P Abraham G Wilfred B Ramakrishna 2000 Plasma prolidase may be an index of liver fibrosis in the rat Clin Chim Acta 295 199 202 10.1016/S0009-8981(00) 00183-2
14. M Gültepe A Ozcan M AltIn G Ozturk M Demirci 1994 Evaluation of the response of hepatic fibrosis to colchicine treatment by estimating serum prolidase activity and procollagen III aminoterminal propeptide levels Turk J Med Sci 20 99 104 (Pubitemid 24068167)
15. O Tarçin N Gedik B Karakoyun V Tahan G Sood C Celikel 2008 Serum prolidase and IGF-1 as non-invasive markers of hepatic fibrosis during four different periods after bile-duct ligation in rats Dig Dis Sci 53 1938 1945 10.1007/s10620-007-0073-1
16. O Tarçin K Avşar L Demirtürk M Gültepe BK Oktar OC Ozdoǧan 2003 In vivo inefficiency of pentoxifylline and interferon-alpha on hepatic fibrosis in biliary-obstructed rats: assessment by tissue collagen content and prolidase activity J Gastroenterol Hepatol 18 437 444 10.1046/j.1440-1746.2003.03004.x
17. FP Chinard 1952 Photometric estimation of proline and ornithine J Biol Chem 199 91 95
18. Brunt EM. Non-alcoholic fatty liver disease. In: Burt AD, Portmann BC, Ferrell LD, eds. MacSween's pathology of the liver. China: Churchill Livingstone Elsevier; 2007:372-379.
19. DM Bolarin EC Azinge 2007 Biochemical markers, extracellular components in liver fibrosis and cirrhosis Nig Q J Hosp Med 17 42 52
20. H Miyaaki T Ichikawa K Nakao H Yatsuhashi R Furukawa K Ohba 2008 Clinicopathological study of nonalcoholic fatty liver disease in Japan: the risk factors for fibrosis Liver Int 28 519 524
21. JM Clark 2006 The epidemiology of nonalcoholic fatty liver disease in adults J Clin Gastroenterol 40 S5 S10
22. JI Zamin AA de Mattos C Perin GZ Ramos 2002 The importance of AST/ALT rate in nonalcoholic steatohepatitis diagnosis Arq Gastroenterol 39 22 26 (Pubitemid 36541483)
23. P Angulo JM Hui G Marchesini E Bugianesi J George GC Farrell 2007 The NAFLD fibrosis score: a noninvasive system that identifies liver fibrosis in patients with NAFLD Hepatology 45 846 854 10.1002/hep.21496
24. FF Verit I Geyikli P Yazgan A Celik 2006 Correlations of serum prolidase activity between bone turnover markers and mineral density in postmenopausal osteoporosis Arch Gynecol Obstet 274 133 137 10.1007/s00404-006-0148-9