Effects of dioxin on vascular endothelial growth factor (VEGF) production in the retina associated with choroidal neovascularization

Investigative Ophthalmology and Visual Science

Volumn 50, Issue 7, 2009, Pages 3410-3416

  Takeuchi, Aya ^a   Takeuchi, Masaru ^a   Oikawa, Kosuke ^a   Sonoda, Koh Hei ^b   Usui, Yoshihiko ^a   Okunuki, Yoko ^a   Takeda, Atsunobu ^b   Oshima, Yuji ^b   Yoshida, Keiichi ^c   Usui, Masahiko ^a   Goto, Hiroshi ^a   Kuroda, Masahiko ^a  

^a TOKYO MEDICAL UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

^c CHIBA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; AROMATIC HYDROCARBON RECEPTOR; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DIOXIN; FLUORESCENT DYE; MESSENGER RNA; VASCULOTROPIN; VASCULOTROPIN A; VASCULOTROPIN B; CYP1B1 PROTEIN, MOUSE; UNSPECIFIC MONOOXYGENASE; VASCULAR ENDOTHELIAL GROWTH FACTOR A, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CILIARY BODY; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; IRIS; LASER COAGULATION; MOUSE; NONHUMAN; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RETINA; SIGNAL TRANSDUCTION; SUBRETINAL NEOVASCULARIZATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; DISEASE MODEL; DRUG EFFECT; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; INTRAPERITONEAL DRUG ADMINISTRATION; METABOLISM; POLLUTANT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UPREGULATION;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; CELLS, CULTURED; CHOROIDAL NEOVASCULARIZATION; CILIARY BODY; CYTOCHROME P-450 CYP1A1; DISEASE MODELS, ANIMAL; ENVIRONMENTAL POLLUTANTS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; INJECTIONS, INTRAPERITONEAL; IRIS; MICE; MICE, INBRED C57BL; RECEPTORS, ARYL HYDROCARBON; RETINA; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TETRACHLORODIBENZODIOXIN; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 67649946260     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.08-2299     Document Type: Article

References (44)

1. Ambati J, Ambati BK, Yoo SH, Ianchulev S, Adamis AP. Age-related macular degeneration: etiology, pathogenesis, and therapeutic strategies. Surv Ophthalmol. 2003;48:257-293.
2. Bressler NM, Bressler SB, Congdon NG, et al. Potential public health impact of Age-Related Eye Disease Study results: AREDS report no. 11. Arch Ophthalmol. 2003;121:1621-1624.
3. Evans JR, Fletcher AE, Wormald RP. Age-related macular degeneration causing visual impairment in people 75 years or older in Britain: an add-on study to the Medical Research Council Trial of Assessment and Management of Older People in the Community. Ophthalmology. 2004;111:513-517.
4. Christen WG, Glynn RJ, Manson JE, Ajani UA, Buring JE. A prospective study of cigarette smoking and risk of age-related macular degeneration in men. JAMA. 1996;276:1147-1151.
5. Smith W, Mitchell P, Leeder SR. Smoking and age-related maculopathy: the Blue Mountains Eye Study. Arch Ophthalmol. 1996;114:1518-1523.
6. Evans JR, Fletcher AE, Wormald RP. 28,000 Cases of age related macular degeneration causing visual loss in people aged 75 years and above in the United Kingdom may be attributable to smoking. Br J Ophthalmol. 2005;89:550-553.
7. Seddon JM, Willett WC, Speizer FE, Hankinson SE. A prospective study of cigarette smoking and age-related macular degeneration in women. JAMA. 1996;276:1141-1146.
8. Delcourt C, Diaz JL, Ponton-Sanchez A, Papoz L. Smoking and age-related macular degeneration: the POLA Study. Pathologies Oculaires Liees a l'Age. Arch Ophthalmol. 1998;116:1031-1035.
9. Green WR, McDonnell PJ, Yeo JH. Pathologic features of senile macular degeneration. Ophthalmology. 1985;92:615-627.
10. Muto H, Takizawa Y. Dioxins in cigarette smoke. Arch Environ Health. 1989;44:171-174.
11. Lofroth G, Zebuhr Y. Polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) in mainstream and sidestream cigarette smoke. Bull Environ Contam Toxicol. 1992;48:789-794.
12. Hoffman EC, Reyes H, Chu FF, et al. Cloning of a factor required for activity of the Ah (dioxin) receptor. Science. 1991;252:954-958.
13. Reyes H, Reiszporszasz S, Hankinson O. Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA-binding form of the Ah receptor. Science. 1992;256:1193-1195.
14. Nebert DW, Dalton TP, Okey AB, Gonzalez FJ. Role of Aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer. J Biol Chem. 2004;279:23847-23850.
15. Schmidt JV, Bradfield CA. Ah receptor signaling pathways. Annu Rev Cell Dev Biol. 1996;12:55-89.
16. Gebremichael A, Tullis K, Denison MS, Cheek JM, Pinkerton KE. Ah-receptor-dependent modulation of gene expression by aged and diluted sidestream cigarette smoke. Toxicol Appl Pharmacol. 1996;141:76-83.
17. Dertinger SD, Nazarenko DA, Silverstone AE, Gasiewicz TA. Aryl hydrocarbon receptor signaling plays a significant role in mediating benzo[a]pyrene-and cigarette smoke condensate-induced cytogenetic damage in vivo. Carcinogenesis. 2001;22:171-177.
18. Kitamura M, Kasai A. Cigarette smoke as a trigger for the dioxin receptor-mediated signaling pathway. Cancer Lett. 2007;252:184-194.
19. Chapman DE, Schiller CM. Dose-related effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in C57BL/6J and DBA/2J mice. Toxicol Appl Pharmacol. 1985;78:147-157.
20. McGregor DB, Partensky C, Wilbourn J, Rice JM. An IARC evaluation of polychlorinated dibenzo-p-dioxins and polychlorinated dibenzofurans as risk factors in human carcinogenesis. Environ Health Perspect. 1998;106:755-760.
21. Oikawa K, Kosugi Y, Ohbayashi T, et al. Increased expression of IgE-dependent histamine-releasing factor in endometriotic implants. J Pathol. 2003;199:318-323.
22. Dunn KC, Aotaki-Keen AE, Putkey FR, Hjelmeland LM. ARPE-19, a human retinal pigment epithelial cell line with differentiated properties. Exp Eye Res. 1996;62:155-169.
23. May CA, Ohlmann AV, Hammes H, Spandau UH. Proteins with an endostatin-like domain in a mouse model of oxygen-induced retinopathy. Exp Eye Res. 2006;82:341-348.
24. Yao XY, Hageman GS, Marmor MF. Recovery of retinal adhesion after enzymatic perturbation of the interphotoreceptor matrix. Invest Ophthalmol Vis Sci. 1992;33:498-503.
25. Nozaki M, Sakurai E, Raisler BJ, et al. Loss of SPARC-mediated VEGFR-1 suppression after injury reveals a novel antiangiogenic activity of VEGF-A. J Clin Invest. 2006;116:422-429.
26. Kleinman ME, Yamada K, Takeda A, et al. Sequence-and targetindependent angiogenesis suppression by siRNA via TLR3. Nature. 2008;452:591-597.
27. Witmer AN, Vrensen GF, Van Noorden CJ, Schlingemann RO. Vascular endothelial growth factors and angiogenesis in eye disease. Prog Retin Eye Res. 2003;22:1-29.
28. Hera R, Keramidas M, Peoc'h M, Mouillon M, Romanet J-P, Feige J-J. Expression of VEGF and angiopoietins in subfoveal membranes from patients with age-related macular degeneration. Am J Ophthalmol. 2005;139:589-596.
29. Marneros AG, Fan J, Yokoyama Y, et al. Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function. Am J Pathol. 2005;167:1451-1459.
30. Simpson DAC, Murphy GM, Bhaduri T, Gardiner TA, Archer DB, Stitt AW. Expression of the VEGF gene family during retinal vasoobliteration and hypoxia. Biochem Biophys Res Commun. 1999; 262:333-340.
31. Kwak N, Okamoto N, Wood JM, Campochiaro PA. VEGF is major stimulator in model of choroidal neovascularization. Invest Ophthalmol Vis Sci. 2000;41:3158-3164.
32. Adamis AP, Shima DT, Yeo KT, et al. Synthesis and secretion of vascular permeability factor/vascular endothelial growth factor by human retinal pigment epithelial cells. Biochem Biophys Res Commun. 1993;193:631-638.
33. Schwesinger C, Yee C, Rohan RM, et al. Intrachoroidal neovascularization in transgenic mice overexpressing vascular endothelial growth factor in the retinal pigment epithelium. Am J Pathol. 2001;158:1161-1172.
34. Gasiewicz TA, Rucci G. Alpha-naphthoflavone acts as an antagonist of 2,3,7, 8-tetrachlorodibenzo-p-dioxin by forming an inactive complex with the Ah receptor. Mol Pharmacol. 1991;40:607-612.
35. Yonekura H, Sakurai S, Liu X, et al. Placenta growth factor and vascular endothelial growth factor B and C expression in microvascular endothelial cells and pericytes: implication in autocrine and paracrine regulation of angiogenesis. J Biol Chem. 1999;274: 35172-35178.
36. Ikeda Y, Yonemitsu Y, Onimaru M, et al. The regulation of vascular endothelial growth factors (VEGF-A, -C, and -D) expression in the retinal pigment epithelium. Exp Eye Res. 2006;83:1031-1040.
37. Richardson AJ, Islam FM, Guymer RH, Cain M, Baird PN. A tagsingle nucleotide polymorphisms approach to the vascular endothelial growth factor-A gene in age-related macular degeneration. Mol Vis. 2007;13:2148-2152.
38. Michaud S-E, Menard C, Guy L-G, Gennaro G, Rivard A. Inhibition of hypoxia-induced angiogenesis by cigarette smoke exposure: impairment of the HIF-1alpha/VEGF pathway. FASEB J. 2003:02-0172fje.
39. Chan WK, Yao G, Gu Y-Z, Bradfield CA. Cross-talk between the aryl hydrocarbon receptor and hypoxia inducible factor signaling pathways: demonstration of competition and compensation. J Biol Chem. 1999;274:12115-12123.
40. Fernandez-Salguero PM, Ward JM, Sundberg JP, Gonzalez FJ. Lesions of aryl-hydrocarbon receptor-deficient mice. Vet Pathol. 1997;34:605-614.
41. Thackaberry EA, Gabaldon DM, Walker MK, Smith SM. Aryl hydrocarbon receptor null mice develop cardiac hypertrophy and increased hypoxia-inducible factor-1α in the absence of cardiac hypoxia. Cardiovasc Toxicol. 2002;2:263-274.
42. Ichihara S, Yamada Y, Ichihara G, et al. A role for the aryl hydrocarbon receptor in regulation of ischemia-induced angiogenesis. Arterioscler Thromb Vasc Biol. 2007;27:1297-1304.
43. Pollenz RS, Davarinos NA, Shearer TP. Analysis of aryl hydrocarbon receptor-mediated signaling during physiological hypoxia reveals lack of competition for the aryl hydrocarbon nuclear translocator transcription factor. Mol Pharmacol. 1999;56:1127-1137.
44. Suner IJ, Espinosa-Heidmann DG, Marin-Castano ME, Hernandez EP, Pereira-Simon S, Cousins SW. Nicotine increases size and severity of experimental choroidal neovascularization. Invest Ophthalmol Vis Sci. 2004;45:311-317.