The effect of extracellular calcium and inorganic phosphate on the growth and osteogenic differentiation of mesenchymal stem cells in vitro: Implication for bone tissue engineering

Biomedical Materials

Volumn 4, Issue 2, 2009, Pages

  Liu, Yu Kan ^a   Lu, Qiao Zhi ^a   Pei, Rui ^b   Ji, Hui Jiao ^a   Zhou, Guo Shun ^c   Zhao, Xiao Li ^a   Tang, Rui Kang ^d   Zhang, Ming ^a  

^a ZHEJIANG UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c HUZHOU CENTRAL HOSPITAL   (China)

^d ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BONE; CALCIUM; CALCIUM ALLOYS; CALCIUM PHOSPHATE; CELL DEATH; CELL MEMBRANES; CELL PROLIFERATION; CONCENTRATION (PROCESS); CORROSION PREVENTION; FLOWCHARTING; MINERALOGY; SCAFFOLDS; SOLAR CONCENTRATORS; TISSUE ENGINEERING;

APOPTOSIS; BONE TISSUE ENGINEERING; BONE-MARROW; CALCIUM IONS; CALCIUM PHOSPHATE CERAMICS; CELL APOPTOSIS; CELL DIFFERENTIATION; CELLULAR EFFECTS; CULTURE MEDIA; EXTRACELLULAR; IN-VITRO; INORGANIC PHOSPHATES; MESENCHYMAL STEM CELL; MTT ASSAYS; OSTEOGENIC DIFFERENTIATION; SEEDED CELLS; STATISTICAL ANALYSIS; TUNEL ASSAY; TWO-WAY ANOVA;

CELL CULTURE;

BETA ACTIN; CALCIUM; CALCIUM ION; CALCIUM PHOSPHATE CERAMIC; COLLAGEN TYPE 1; OSTEOCALCIN; PHOSPHATE; RNA; ALKALINE PHOSPHATASE; CALCIUM PHOSPHATE; COLLAGEN; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE;

ANALYSIS OF VARIANCE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE DEVELOPMENT; BONE TISSUE; CALCIUM CELL LEVEL; CELL DIFFERENTIATION; CELL GROWTH; CONCENTRATION RESPONSE; CONTROLLED STUDY; IN VITRO STUDY; MESENCHYMAL STEM CELL; MINERALIZATION; NICK END LABELING; NONHUMAN; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STAINING; STATISTICAL ANALYSIS; TISSUE ENGINEERING; VONKOSSA STAINING; BONE; CELL PROLIFERATION; CHEMISTRY; CYTOLOGY; HUMAN; METABOLISM; METHODOLOGY;

ORYCTOLAGUS CUNICULUS;

ALKALINE PHOSPHATASE; BONE AND BONES; CALCIUM; CALCIUM PHOSPHATES; CELL DIFFERENTIATION; CELL PROLIFERATION; COLLAGEN; HUMANS; MESENCHYMAL STEM CELLS; OSTEOCALCIN; OSTEOGENESIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TETRAZOLIUM SALTS; THIAZOLES; TISSUE ENGINEERING;

EID: 67649900161     PISSN: 17486041     EISSN: 1748605X     Source Type: Journal    
DOI: 10.1088/1748-6041/4/2/025004     Document Type: Article

References (25)

1. Hosseinkhani H, Hosseinkhani M and Kobayashi H 2006 Proliferation and differentiation of mesenchymal stem cells using self-assembled peptide amphiphile nanofibers Biomed. Mater. 1 8-15
2. Hosseinkhani H, Hosseinkhani M, Khademhosseini A, Kobayashi H and Tabata Y 2006 Enhanced angiogenesis through controlled release of basic fibroblast growth factor from peptide amphiphile for tissue regeneration Biomaterials 27 5836-44 (Pubitemid 44287028)
3. Hosseinkhani H, Hosseinkhani M, Tian F, Kobayashi H and Tabata Y 2006 Osteogenic differentiation of mesenchymal stem cells in self-assembled peptide-amphiphile nanofibers Biomaterials 27 4079-86
4. Hosseinkhani H, Yamamoto M, Inatsugu Y, Hiraoka Y, Inoue S, Shimokawa H and Tabata Y 2006 Enhanced ectopic bone formation using a combination of plasmid DNA impregnation into 3-D scaffold and bioreactor perfusion culture Biomaterials 27 1387-98 (Pubitemid 41739564)
5. Hosseinkhani H, Hosseinkhani M, Khademhosseini A and Kobayashi H 2007 Bone regeneration through controlled release of bone morphogenetic protein-2 from 3-D tissue engineered nano-scaffold J. Control. Release 26 380-6 (Pubitemid 46216579)
6. Hosseinkhani H, Hosseinkhani M, Gabrielson N P, Pack D W, Khademhosseini A and Kobayashi H 2008 DNA nanoparticles encapsulated in 3D tissue-engineered scaffolds enhance osteogenic differentiation of mesenchymal stem cells J. Biomed. Mater. Res. A 85 47-60 (Pubitemid 351355354)
7. Li X, van Blitterswijk C A, Feng Q, Cui F and Watari F 2008 The effect of calcium phosphate microstructure on bone-related cells in vitro Biomaterials 29 3306-16
8. Wang J, Zhao H, Zhou S, Lu X, Feng B, Duan C and Weng J 2008 One-step in situ synthesis and characterization of sponge-like porous calcium phosphate scaffolds using a sol-gel and gel casting hybrid process J. Biomed. Mater. Res. A online, doi:10.1002/jbm.a.32089
9. Trojani C, Boukhechba F, Scimeca J C, Vandenbos F, Michiels J F, Daculsi G, Boileau P, Weiss P, Carle G F and Rochet N 2006 Ectopic bone formation using an injectable biphasic calcium phosphate/Si-HPMC hydrogel composite loaded with undifferentiated bone marrow stromal cells Biomaterials 27 3256-64 (Pubitemid 43348526)
10. Laschke M W, Witt K, Pohlemann T and Menger M D 2007 Injectable nanocrystalline hydroxyapatite paste for bone substitution: in vivo analysis of biocompatibility and vascularization J. Biomed. Mater. Res. B 82 494-505
11. Pittenger M F, Mackay A M, Beck S C, Jaiswal R K, Douglas R, Mosca J D, Moorman M A, Simonetti D W, Craig S and Marshak D R 1999 Multilineage potential of adult human mesenchymal stem cells Science 284 143-7 (Pubitemid 29282067)
12. Salgado A J, Coutinho O P and Reis R L 2004 Bone tissue engineering: state of the art and future trends Macromol. Biosci. 4 743-65 (Pubitemid 39257140)
13. Kim H W, Kim H E and Salih V 2005 Stimulation of osteoblast responses to biomimetic nanocomposites of gelatin-hydroxyapatite for tissue engineering scaffolds Biomaterials 26 5221-30 (Pubitemid 40387844)
14. Liu Y K, Wang G C, Cai Y R, Ji H J, Zhou G S, Zhao X L, Tang R K and Zhang M 2008 In vitro effects of nanophase hydroxyapatite particles on proliferation and osteogenic differentiation of bone marrow derived mesenchymal stem cells J. Biomed. Mater. Res. A online, doi:10.1002/jbm.a.32192
15. Lin T M, Tsai J L, Lin S D, Lai C S and Chang C C 2005 Accelerated growth and prolonged lifespan of adipose tissue-derived human mesenchymal stem cells in a medium using reduced calcium and antioxidants Stem Cell Dev. 14 92-102
16. Chang Y L, Stanford C M and Keller J C 2000 Calcium and phosphate supplementation promotes bone cell mineralization: implications for hydroxyapatite-enhanced bone formation J. Biomed. Mater. Res 52 270-8 (Pubitemid 30646798)
17. Zhou G S, Su Z Y, Cai Y R, Liu Y K, Dai L C, Tang R K and Zhang M 2007 Different effects of nanophase and conventional hydroxyapatite thin films on attachment, proliferation and osteogenic differentiation of bone marrow derived mesenchymal stem cells Biomed. Mater. Eng. 17 387-95 (Pubitemid 350136498)
18. Zayzafoon M 2006 Calcium/calmodulin signaling controls osteoblast growth and differentiation J. Cell Biochem. 97 56-70 (Pubitemid 43050179)
19. Nemeth E F and Carafoli E 1990 The role of extracellular calcium in the regulation of intracellular calcium and cell function Cell Calcium 11 319-21 (Pubitemid 20153811)
20. Meleti Z, Shapiro I M and Adams C S 2000 Inorganic phosphate induces apoptosis of osteoblast-like cells in culture Bone 27 359-66 (Pubitemid 30658118)
21. Castano-Izquierdo H, Alvarez-Barreto J, van den Dolder J, Jansen J A, Mikos A G and Sikavitsas V I 2007 Pre-culture period of mesenchymal stem cells in osteogenic media influences their in vivo bone forming potential J. Biomed. Mater. Res. A 82 129-38 (Pubitemid 46906498)
22. Hamada K, Hirose M, Yamashita T and Ohgushi H 2008 Spatial distribution of mineralized bone matrix produced by marrow mesenchymal stem cells in self-assembling peptide hydrogel scaffold J. Biomed. Mater. Res. A 84 128-36 (Pubitemid 350244254)
23. Hoemann C D, Chenite A, Sun J, Hurtig M, Serreqi A, Lu Z, Rossomacha E and Buschmann M D 2007 Cytocompatible gel formation of chitosan-glycerol phosphate solutions supplemented with hydroxyl ethyl cellulose is due to the presence of glyoxal J. Biomed. Mater. Res. A 83 521-9 (Pubitemid 47557403)
24. Zhu N, Cui F Z, Hu K and Zhu L 2007 Biomedical modification of poly(L-lactide) by blending with lecithin J. Biomed. Mater. Res. A 82 455-61 (Pubitemid 47051677)
25. Liu H, Raghavan D and Stubbs J III 2007 Evaluation of the biological responses of osteoblast-like UMR-106 cells to the engineered porous PHBV matrix J. Biomed. Mater. Res. A 81 669-77 (Pubitemid 46786898)