Determinants of subcellular localization of the rubella virus nonstructural replicase proteins

Virology

Volumn 390, Issue 2, 2009, Pages 315-323

  Matthews, Jason D ^a   Tzeng, Wen Pin ^a   Frey, Teryl K ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

Author keywords

Membrane association; Nonstructural protein localization; Replication complex

Indexed keywords

LYSOSOME ASSOCIATED MEMBRANE PROTEIN 2; NONSTRUCTURAL REPLICASE PROTEIN; PROTEIN P 150; PROTEIN P90; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; ENDOSOME; GENETIC TRANSFECTION; LYSOSOME; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; RNA REPLICATION; RNA SYNTHESIS; RUBELLA VIRUS; VERO CELL;

ANIMALS; BINDING SITES; CELL MEMBRANE; CERCOPITHECUS AETHIOPS; CYTOPLASM; MICROSCOPY, CONFOCAL; PROTEIN BINDING; PROTEIN TRANSPORT; RNA REPLICASE; RUBELLA VIRUS; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS;

RUBELLA VIRUS;

EID: 67649881099     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2009.05.019     Document Type: Article

References (30)

1. Ahola T., Kujala P., Tuittila M., Blom T., Laakkonen P., Hinkkanen A., and Auvinen P. Effects of palmitoylation of replicase protein nsP1 on alphavirus infection. J. Virol. 74 15 (2000) 6725-6733
2. den Boon J.A., Chen J., and Ahlquist P. Identification of sequences in Brome mosaic virus replicase protein 1a that mediate association with endoplasmic reticulum membranes. J. Virol. 75 24 (2001) 12370-12381
3. Fontana J., Tzeng W.P., Calderita G., Fraile-Ramos A., Frey T.K., and Risco C. Novel replication complex architecture in rubella replicon-transfected cells. Cell Microbiol. 9 4 (2007) 875-890
4. Forng R.Y., and Frey T.K. Identification of the rubella virus nonstructural proteins. Virology 206 2 (1995) 843-853
5. Frey T.K. Molecular biology of rubella virus. Adv. Virus Res. 44 (1994) 69-160
6. Froshauer S., Kartenbeck J., and Helenius A. Alphavirus RNA replicase is located on the cytoplasmic surface of endosomes and lysosomes. J. Cell Biol. 107 6 Pt 1 (1988) 2075-2086
7. Gorchakov R., Garmashova N., Frolova E., and Frolov I. Different types of nsP3-containing protein complexes in Sindbis virus-infected cells. J. Virol. 82 20 (2008) 10088-10101
8. Hobman T.C. Targeting of viral glycoproteins to the Golgi complex. Trends Microbiol. 1 4 (1993) 124-130
9. Hobman T.C., Woodward L., and Farquhar M.G. The rubella virus E2 and E1 spike glycoproteins are targeted to the Golgi complex. J. Cell Biol. 121 2 (1993) 269-281
10. Hobman T.C., Woodward L., and Farquhar M.G. Targeting of a heterodimeric membrane protein complex to the Golgi: rubella virus E2 glycoprotein contains a transmembrane Golgi retention signal. Mol. Biol. Cell 6 1 (1995) 7-20
11. Imai M., Watanabe S., Ninomiya A., Obuchi M., and Odagiri T. Influenza B virus BM2 protein is a crucial component for incorporation of viral ribonucleoprotein complex into virions during virus assembly. J. Virol. 78 20 (2004) 11007-11015
12. Kaariainen L., and Ahola T. Functions of alphavirus nonstructural proteins in RNA replication. Prog. Nucleic Acid Res. Mol. Biol. 71 (2002) 187-222
13. Kong F., Sivakumaran K., and Kao C. The N-terminal half of the brome mosaic virus 1a protein has RNA capping-associated activities: specificity for GTP and S-adenosylmethionine. Virology 259 1 (1999) 200-210
14. Kujala P., Ahola T., Ehsani N., Auvinen P., Vihinen H., and Kaariainen L. Intracellular distribution of rubella virus nonstructural protein P150. J. Virol. 73 9 (1999) 7805-7811
15. Lee J.Y., Marshall J.A., and Bowden D.S. Characterization of rubella virus replication complexes using antibodies to double-stranded RNA. Virology 200 1 (1994) 307-312
16. Liang Y., and Gillam S. Rubella virus RNA replication is cis-preferential and synthesis of negative- and positive-strand RNAs is regulated by the processing of nonstructural protein. Virology 282 2 (2001) 307-319
17. Lyle J.M., Bullitt E., Bienz K., and Kirkegaard K. Visualization and functional analysis of RNA-dependent RNA polymerase lattices. Science 296 5576 (2002) 2218-2222
18. Magliano D., Marshall J.A., Bowden D.S., Vardaxis N., Meanger J., and Lee J.Y. Rubella virus replication complexes are virus-modified lysosomes. Virology 240 1 (1998) 57-63
19. Novoa R.R., Calderita G., Arranz R., Fontana J., Granzow H., and Risco C. Virus factories: associations of cell organelles for viral replication and morphogenesis. Biol. Cell 97 2 (2005) 147-172
20. Peranen J., Laakkonen P., Hyvonen M., and Kaariainen L. The alphavirus replicase protein nsP1 is membrane-associated and has affinity to endocytic organelles. Virology 208 2 (1995) 610-620
21. Rozanov M.N., Koonin E.V., and Gorbalenya A.E. Conservation of the putative methyltransferase domain: a hallmark of the 'Sindbis-like' supergroup of positive-strand RNA viruses. J. Gen. Virol. 73 Pt 8 (1992) 2129-2134
22. Salonen A., Vasiljeva L., Merits A., Magden J., Jokitalo E., and Kaariainen L. Properly folded nonstructural polyprotein directs the Semliki forest virus replication complex to the endosomal compartment. J. Virol. 77 3 (2003) 1691-1702
23. Shi S.T., Lee K.J., Aizaki H., Hwang S.B., and Lai M.M. Hepatitis C virus RNA replication occurs on a detergent-resistant membrane that cofractionates with caveolin-2. J. Virol. 77 7 (2003) 4160-4168
24. Spuul P., Salonen A., Merits A., Jokitalo E., Kaariainen L., and Ahola T. Role of the amphipathic peptide of Semliki forest virus replicase protein nsP1 in membrane association and virus replication. J. Virol. 81 2 (2007) 872-883
25. Tzeng W.P., and Frey T.K. Mapping the rubella virus subgenomic promoter. J. Virol. 76 7 (2002) 3189-3201
26. Tzeng W.P., and Frey T.K. Complementation of a deletion in the rubella virus p150 nonstructural protein by the viral capsid protein. J. Virol. 77 17 (2003) 9502-9510
27. Tzeng W.P., and Frey T.K. C-E1 fusion protein synthesized by rubella virus DI RNAs maintained during serial passage. Virology 356 1-2 (2006) 198-207
28. Tzeng W.P., Chen M.H., Derdeyn C.A., and Frey T.K. Rubella virus DI RNAs and replicons: requirement for nonstructural proteins acting in cis for amplification by helper virus. Virology 289 1 (2001) 63-73
29. Tzeng W.P., Matthews J.D., and Frey T.K. Analysis of rubella virus capsid protein-mediated enhancement of replicon replication and mutant rescue. J. Virol. 80 8 (2006) 3966-3974
30. Zusinaite E., Tints K., Kiiver K., Spuul P., Karo-Astover L., Merits A., and Sarand I. Mutations at the palmitoylation site of non-structural protein nsP1 of Semliki Forest virus attenuate virus replication and cause accumulation of compensatory mutations. J. Gen. Virol. 88 Pt. 7 (2007) 1977-1985