-
1
-
-
4344559350
-
Tissue-selectivity: The mechanism of action of tibolone
-
Kloosterboer H. Tissue-selectivity: the mechanism of action of tibolone. Maturitas 2004;48:S30-S40.
-
(2004)
Maturitas
, vol.48
-
-
Kloosterboer, H.1
-
2
-
-
0034987346
-
Tibolone: A steroid with a tissue specific mode of action
-
Kloosterboer H. Tibolone: a steroid with a tissue specific mode of action. J Steroid Biochem Mol Biol 2001;76:231-238.
-
(2001)
J Steroid Biochem Mol Biol
, vol.76
, pp. 231-238
-
-
Kloosterboer, H.1
-
3
-
-
0001939751
-
Tibolone and its metabolites: Pharmacology, tissue specificity and effects in animal models of tumors
-
Kloosterboer H. Tibolone and its metabolites: pharmacology, tissue specificity and effects in animal models of tumors. Gynecol Endocrinol 1997;11:63-68.
-
(1997)
Gynecol Endocrinol
, vol.11
, pp. 63-68
-
-
Kloosterboer, H.1
-
4
-
-
0036146189
-
Tibolone for postmenopausal women: Systematic review of randomised trials
-
Modelska K, Cummings G. Tibolone for postmenopausal women: systematic review of randomised trials. J Clin Endocrinol Metab 2002; 87:16-23.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 16-23
-
-
Modelska, K.1
Cummings, G.2
-
5
-
-
0037211578
-
Receptor profiling and endocrine interactions of tibolone
-
DeGooyer ME, Deckers GH, Schoonen WG, Verheul HA, Kloosterboer HJ. Receptor profiling and endocrine interactions of tibolone. Steroids 2003;68:21-30.
-
(2003)
Steroids
, vol.68
, pp. 21-30
-
-
DeGooyer, M.E.1
Deckers, G.H.2
Schoonen, W.G.3
Verheul, H.A.4
Kloosterboer, H.J.5
-
6
-
-
18144451220
-
Tibolone: A compound with tissue specific inhibitory effects on sulfatase
-
DeGooyer ME, Kleyn GT, Smits KC, Ederveen AG, Verheul HA, Kloosterboer HJ. Tibolone: a compound with tissue specific inhibitory effects on sulfatase. Mol Cell Endocrinol 2001;183:55-62.
-
(2001)
Mol Cell Endocrinol
, vol.183
, pp. 55-62
-
-
DeGooyer, M.E.1
Kleyn, G.T.2
Smits, K.C.3
Ederveen, A.G.4
Verheul, H.A.5
Kloosterboer, H.J.6
-
7
-
-
4344581290
-
Tibolone: A selective tissue estrogenic activity regulator (STEAR)
-
Reed M, Kloosterboer H. Tibolone: a selective tissue estrogenic activity regulator (STEAR). Maturitas 2004;48:S4-S6.
-
(2004)
Maturitas
, vol.48
-
-
Reed, M.1
Kloosterboer, H.2
-
8
-
-
34249981465
-
Tibolone and its delta-4,7α-methyl norethisterone metabolite are reversible inhibitors of human aromatase
-
Raobaikady B, Parsons MF, Reed MJ, Purohit A. Tibolone and its delta-4,7α-methyl norethisterone metabolite are reversible inhibitors of human aromatase. J Steroid Biochem Mol Biol 2007;104:154-160.
-
(2007)
J Steroid Biochem Mol Biol
, vol.104
, pp. 154-160
-
-
Raobaikady, B.1
Parsons, M.F.2
Reed, M.J.3
Purohit, A.4
-
9
-
-
34548506770
-
Interactions of the human cytosolic sulfotransferases and steroid sulfatase in the metabolism of tibolone and raloxifene
-
Falany J, Falany C. Interactions of the human cytosolic sulfotransferases and steroid sulfatase in the metabolism of tibolone and raloxifene. J Steroid Biochem Mol Biol 2007;107:202-210.
-
(2007)
J Steroid Biochem Mol Biol
, vol.107
, pp. 202-210
-
-
Falany, J.1
Falany, C.2
-
10
-
-
33646074319
-
Sulfation of tibolone metabolites by human postmenopausal liver and small intestinal sulfotransferases (SULTs)
-
Wang M, Ebmeier CC, Olin JR, Anderson RJ. Sulfation of tibolone metabolites by human postmenopausal liver and small intestinal sulfotransferases (SULTs). Steroids 2006;71:343-351.
-
(2006)
Steroids
, vol.71
, pp. 343-351
-
-
Wang, M.1
Ebmeier, C.C.2
Olin, J.R.3
Anderson, R.J.4
-
11
-
-
34250760856
-
Selective tissue distribution of tibolone metabolites in mature ovariectomised female cynomolgus monkeys after multiple doses of tibolone
-
Verheul H, van Jersel ML, Delbressine LP, Kloosterboer HJ. Selective tissue distribution of tibolone metabolites in mature ovariectomised female cynomolgus monkeys after multiple doses of tibolone. Drug Metab Dispos 2007;35:1105-1111.
-
(2007)
Drug Metab Dispos
, vol.35
, pp. 1105-1111
-
-
Verheul, H.1
van Jersel, M.L.2
Delbressine, L.P.3
Kloosterboer, H.J.4
-
12
-
-
33846883071
-
J lao X. Changes in intra-abdominal fat in early postmenopausal women: Effects of hormone use
-
Gower B, Muñoz J, Desmond R, Hilario-Hailey T, J lao X. Changes in intra-abdominal fat in early postmenopausal women: effects of hormone use. Obesity 2006;14:1046-1055.
-
(2006)
Obesity
, vol.14
, pp. 1046-1055
-
-
Gower, B.1
Muñoz, J.2
Desmond, R.3
Hilario-Hailey, T.4
-
13
-
-
12944276957
-
Aromatase deficient (ArKO) mice have a phenotype of increased adiposity
-
Jones ME, Thorbum AW, Britt KL, et al. Aromatase deficient (ArKO) mice have a phenotype of increased adiposity. Proc Natl Acad Sci U S A 2000;97:12735-12740.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 12735-12740
-
-
Jones, M.E.1
Thorbum, A.W.2
Britt, K.L.3
-
14
-
-
0037387209
-
Cellular and molecular characterisation of the adipose pheno-type of the aromatase deficient mouse
-
Misso ME, Murato Y, Boor WC, Jones ME, Britt KL, Simpson ER. Cellular and molecular characterisation of the adipose pheno-type of the aromatase deficient mouse. Endocrinology 2003;144: 1474-1480.
-
(2003)
Endocrinology
, vol.144
, pp. 1474-1480
-
-
Misso, M.E.1
Murato, Y.2
Boor, W.C.3
Jones, M.E.4
Britt, K.L.5
Simpson, E.R.6
-
15
-
-
0018633313
-
Recent advances in studies of estrogen biosynthesis
-
Brodie A. Recent advances in studies of estrogen biosynthesis. J Endocrinol Invest 1979;2:445-460.
-
(1979)
J Endocrinol Invest
, vol.2
, pp. 445-460
-
-
Brodie, A.1
-
16
-
-
0032499704
-
Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene
-
Fisher CR, Graves KH, Parlow AF, Simpson ER. Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene. Proc Natl Acad Sci U S A 1998;95:6965-6970.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 6965-6970
-
-
Fisher, C.R.1
Graves, K.H.2
Parlow, A.F.3
Simpson, E.R.4
-
17
-
-
18844461988
-
Estrogen - the good, the bad and the unexpected
-
Simpson ER, Misso M, Hewitt KN, et al. Estrogen - the good, the bad and the unexpected. Endocr Rev 2005;26:322-330.
-
(2005)
Endocr Rev
, vol.26
, pp. 322-330
-
-
Simpson, E.R.1
Misso, M.2
Hewitt, K.N.3
-
18
-
-
34548436968
-
Estrogen and adiposity - utilizing models of aromatase deficiency to explore the relationship
-
Jones ME, McInnes KJ, Boon WC, Simpson ER. Estrogen and adiposity - utilizing models of aromatase deficiency to explore the relationship. J Steroid Biochem Mol Biol 2007;106:3-7.
-
(2007)
J Steroid Biochem Mol Biol
, vol.106
, pp. 3-7
-
-
Jones, M.E.1
McInnes, K.J.2
Boon, W.C.3
Simpson, E.R.4
-
20
-
-
13944273356
-
Cholesterol feeding prevents adiposity in the obese female aromatase knockout (ArKO) mouse
-
Misso ML, Hewitt KN, Boon WC, et al. Cholesterol feeding prevents adiposity in the obese female aromatase knockout (ArKO) mouse. Horm Metab Res 2005;37:26-31.
-
(2005)
Horm Metab Res
, vol.37
, pp. 26-31
-
-
Misso, M.L.1
Hewitt, K.N.2
Boon, W.C.3
-
22
-
-
20444466531
-
Low-density lipoprotein cholesterol estimation by a new formula in Indian population
-
Anandaraja S, Narang R, Godeswar R, Laksmy R, Talwar KK. Low-density lipoprotein cholesterol estimation by a new formula in Indian population. Int J Cardiol 2005;102:117-120.
-
(2005)
Int J Cardiol
, vol.102
, pp. 117-120
-
-
Anandaraja, S.1
Narang, R.2
Godeswar, R.3
Laksmy, R.4
Talwar, K.K.5
-
23
-
-
23844503944
-
Oestrogen replacement in vivo rescues the dysfunction of pituitary somatotropes in ovariectomised aromatase knockout mice
-
Yan M, Jones ME, Hernandez M, Liu D, Simpson ER, Chen C. Oestrogen replacement in vivo rescues the dysfunction of pituitary somatotropes in ovariectomised aromatase knockout mice. Neuroendocrinology 2005;81:158-166.
-
(2005)
Neuroendocrinology
, vol.81
, pp. 158-166
-
-
Yan, M.1
Jones, M.E.2
Hernandez, M.3
Liu, D.4
Simpson, E.R.5
Chen, C.6
-
24
-
-
33748157097
-
Ovarian feedback, mechanism of action and possible clinical implications
-
Massinis IE. Ovarian feedback, mechanism of action and possible clinical implications. Hum Reprod 2006;12:557-571.
-
(2006)
Hum Reprod
, vol.12
, pp. 557-571
-
-
Massinis, I.E.1
-
25
-
-
33751517959
-
Regulation of adenosine 5′-monophosphate-activated protein kinase and lipogenesis by androgens contributes to visceral obesity in an estrogen deficient state
-
McInnes KJ, Corbould A, Simpson ER, Jones ME. Regulation of adenosine 5′-monophosphate-activated protein kinase and lipogenesis by androgens contributes to visceral obesity in an estrogen deficient state. Endocrinology 2006;147:5907-5913.
-
(2006)
Endocrinology
, vol.147
, pp. 5907-5913
-
-
McInnes, K.J.1
Corbould, A.2
Simpson, E.R.3
Jones, M.E.4
-
26
-
-
15744382734
-
Hormonal regulation and localization of estrogen, progestin and androgen receptors in the endometrium of nonhuman primates: Effects of progesterone receptor antagonists
-
Slayden O, Brenner R. Hormonal regulation and localization of estrogen, progestin and androgen receptors in the endometrium of nonhuman primates: effects of progesterone receptor antagonists. Arch Histol Cytol 2004;67:393-409.
-
(2004)
Arch Histol Cytol
, vol.67
, pp. 393-409
-
-
Slayden, O.1
Brenner, R.2
-
27
-
-
33746045998
-
Serum leptin levels and body composition in postmenopausal women treated with tibolone and raloxifene
-
Tommaselli GA, Di Carlo C, Di Spiezio Sandro A, et al. Serum leptin levels and body composition in postmenopausal women treated with tibolone and raloxifene. Menopause 2006;13:660-668.
-
(2006)
Menopause
, vol.13
, pp. 660-668
-
-
Tommaselli, G.A.1
Di Carlo, C.2
Di Spiezio Sandro, A.3
-
28
-
-
33847340134
-
Effects of tibolone on abdominal subcutaneous fat, serum leptin levels, and anthropometric indices: A 6-month, prospective, randomized, placebo-controlled, double-blind study
-
Odabasi AR, Yuksel H, Kafkas S, et al. Effects of tibolone on abdominal subcutaneous fat, serum leptin levels, and anthropometric indices: a 6-month, prospective, randomized, placebo-controlled, double-blind study. Adv Ther 2006;23:926-937.
-
(2006)
Adv Ther
, vol.23
, pp. 926-937
-
-
Odabasi, A.R.1
Yuksel, H.2
Kafkas, S.3
-
29
-
-
0042421820
-
The aromatase knockout mouse presents with a sexually dimorphic disruption to cholesterol homeostasis
-
Hewitt KCN, Boon WC, Muvata Y, Jones ME, Simpson ER. The aromatase knockout mouse presents with a sexually dimorphic disruption to cholesterol homeostasis. Endocrinology 2003;144:3895-3903.
-
(2003)
Endocrinology
, vol.144
, pp. 3895-3903
-
-
Hewitt, K.C.N.1
Boon, W.C.2
Muvata, Y.3
Jones, M.E.4
Simpson, E.R.5
-
30
-
-
0031033809
-
Effect of tibolone on glucose and lipid metabolism in postmenopausal women
-
Cagnacci A, Mallas E, Tuveri F. Effect of tibolone on glucose and lipid metabolism in postmenopausal women J Clin Endocrinol Metab 1997; 82:251-253.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 251-253
-
-
Cagnacci, A.1
Mallas, E.2
Tuveri, F.3
-
31
-
-
0033021377
-
High resolution ultrasound assessment of the carotid artery: Its relevance in postmenopausal women and the effects of tibolone on carotid artery ultrastructure
-
Morris E, Denton E, Robinson J. High resolution ultrasound assessment of the carotid artery: its relevance in postmenopausal women and the effects of tibolone on carotid artery ultrastructure. Climacteric 1999;2: 13-20.
-
(1999)
Climacteric
, vol.2
, pp. 13-20
-
-
Morris, E.1
Denton, E.2
Robinson, J.3
-
32
-
-
0034455288
-
An age related ovarian phenotype in mice with targeted disruption of the Cyp 19 (aromatase) gene
-
Britt KL, Drummond AE, Cox VA, et al. An age related ovarian phenotype in mice with targeted disruption of the Cyp 19 (aromatase) gene. Endocrinology 2000;141:2614-2623.
-
(2000)
Endocrinology
, vol.141
, pp. 2614-2623
-
-
Britt, K.L.1
Drummond, A.E.2
Cox, V.A.3
-
33
-
-
0032239547
-
Pathophysiology of the neuroregulation of GH secretion in experimental animals and humans
-
Giustina A, Veldhuis J. Pathophysiology of the neuroregulation of GH secretion in experimental animals and humans. Endocr Rev 1998;19: 717-797.
-
(1998)
Endocr Rev
, vol.19
, pp. 717-797
-
-
Giustina, A.1
Veldhuis, J.2
-
34
-
-
1642401412
-
Estradiol supplementation modulates growth hormone (GH) secretory-burst waveform and recombinant human insulin like growth factor-1- enforced suppression of endogenously driven GH release in postmenopausal women
-
Veldhuis JD, Anderson SM, Kok P, et al. Estradiol supplementation modulates growth hormone (GH) secretory-burst waveform and recombinant human insulin like growth factor-1- enforced suppression of endogenously driven GH release in postmenopausal women. J Clin Endocrinol Metab 2004;89:1312-1318.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 1312-1318
-
-
Veldhuis, J.D.1
Anderson, S.M.2
Kok, P.3
-
35
-
-
34547950312
-
Postmenopausal HRT and tibolone in relation to muscle strength and body composition
-
Jacobsen DCE, Samson MM, Kezic S, Verhaar HJ. Postmenopausal HRT and tibolone in relation to muscle strength and body composition. Maturitas 2007;58:7-18.
-
(2007)
Maturitas
, vol.58
, pp. 7-18
-
-
Jacobsen, D.C.E.1
Samson, M.M.2
Kezic, S.3
Verhaar, H.J.4
-
36
-
-
0030657579
-
Modulatory effects of a synthetic steroid (tibolone) and estradiol on spontaneous and GH-RH induced GH secretion in postmenopausal women
-
Genazzani AD, Gamba O, Nappi L, Volpe A, Petraglia F. Modulatory effects of a synthetic steroid (tibolone) and estradiol on spontaneous and GH-RH induced GH secretion in postmenopausal women. Maturitas 1997;28:27-33.
-
(1997)
Maturitas
, vol.28
, pp. 27-33
-
-
Genazzani, A.D.1
Gamba, O.2
Nappi, L.3
Volpe, A.4
Petraglia, F.5
-
37
-
-
0034912496
-
Targeted disruption of the aromatase P450 gene (Cyp19) in mice and their ovarian and uterine responses to 17A-oestradiol
-
Toda K, Takeda K, Okada T, et al. Targeted disruption of the aromatase P450 gene (Cyp19) in mice and their ovarian and uterine responses to 17A-oestradiol. J Endocrinol 2001;170:99-111.
-
(2001)
J Endocrinol
, vol.170
, pp. 99-111
-
-
Toda, K.1
Takeda, K.2
Okada, T.3
-
38
-
-
33748065320
-
Metabolism of tibolone and its metabolites in uterine and vaginal tissue of rats and human origin
-
Blom MJ, Wassink MG, De Gooyer ME, et al. Metabolism of tibolone and its metabolites in uterine and vaginal tissue of rats and human origin. J Steroid Biochem Mol Biol 2006;101:42-49.
-
(2006)
J Steroid Biochem Mol Biol
, vol.101
, pp. 42-49
-
-
Blom, M.J.1
Wassink, M.G.2
De Gooyer, M.E.3
-
39
-
-
24944522450
-
Tibolone and its metabolites enhance tissue factor and PAI-1 expression in human endometrial stromal cells: Evidence of progestogenic effect
-
Schatz F, Kuczynski E, Kloosterhoer HJ, et al. Tibolone and its metabolites enhance tissue factor and PAI-1 expression in human endometrial stromal cells: evidence of progestogenic effect. Steroids 2005;70:840-845.
-
(2005)
Steroids
, vol.70
, pp. 840-845
-
-
Schatz, F.1
Kuczynski, E.2
Kloosterhoer, H.J.3
-
41
-
-
20044384893
-
Molecular portrait of the progestogenic and estrogenic actions of tibolone: Behaviour of cellular networks in response to tibolone
-
Hanifi-Moghaddam P, Gielen SC, Kloosterboer HJ, et al. Molecular portrait of the progestogenic and estrogenic actions of tibolone: behaviour of cellular networks in response to tibolone. J Clin Endocrinol Metab 2005;90:973-983.
-
(2005)
J Clin Endocrinol Metab
, vol.90
, pp. 973-983
-
-
Hanifi-Moghaddam, P.1
Gielen, S.C.2
Kloosterboer, H.J.3
|