Modulatory effects of a synthetic steroid (tibolone) and estradiol on spontaneous and gh-rh-induced gh secretion in postmenopausal women

Maturitas

Volumn 28, Issue 1, 1997, Pages 27-33

  Genazzani, Alessandro D ^a   Gamba, Ombretta ^a   Nappi, Luigi ^a   Volpe, Annibale ^a   Petraglia, Felice ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

Author keywords

Hormonal replacement therapy; Plasma GH; Tibolone; Transdermal estradiol

Indexed keywords

ESTRADIOL; TIBOLONE;

ARTICLE; CLINICAL ARTICLE; ESTROGEN THERAPY; FEMALE; GROWTH HORMONE BLOOD LEVEL; GROWTH HORMONE RELEASE; HUMAN; POSTMENOPAUSE; TRANSDERMAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

ADMINISTRATION, CUTANEOUS; ANABOLIC AGENTS; BODY MASS INDEX; DOSE-RESPONSE RELATIONSHIP, DRUG; ESTRADIOL; ESTROGEN REPLACEMENT THERAPY; FEMALE; FOLLICLE STIMULATING HORMONE; GROWTH HORMONE-RELEASING HORMONE; HUMAN GROWTH HORMONE; HUMANS; INSULIN-LIKE GROWTH FACTOR I; LUTEINIZING HORMONE; NORPREGNENES; POSTMENOPAUSE;

EID: 0030657579     PISSN: 03785122     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-5122(97)00049-2     Document Type: Article

References (26)

1. Rossmanith WG, Scherbaum WA, Lauritzen C. Gonadotropin secretion during aging in postmenopausal women. Neuroendocrinology 1991;54:211-8.
2. Lauritzen C. The hypothalamic anterior pituitary system in the climacteric age period. In: Van Keep PA, Lauritzen C, editors. Frontiers in Hormone Research, Vol. 3. Basel:Karger, 1975:20-29.
3. Yen SSC. The biology of menopause. J Reprod Med 1977;18:287-96.
4. Chakravarti S, Collins WP, Forecast JD, Newton JR, Oram DH, Studd JWW. Hormonal profiles after menopause. Br Med J 1976;II:784-786.
5. Alexander SE, Aksel S, Hazelton JM, Yeoman RR, Gilmore SM. The effect of aging on hypothalamic function in oophorectomized women. Am J Obstet Gynecol 1990;162:446449.
6. Genazzani AD, Petraglia F, Sgarbi L, Montanini V, Hartmann B, Surico N, Biolcati A, Volpe A, Genazzani AR. Difference of LH and FSH secretory characteristics and degree of concordance between postmenopausal and aging women. Maturitas 1997 (in press).
7. Bellantoni MF, Harman SM, Cho DE, Blagman MR. Effects of progestin-opposed transdermal estrogen administration on growth hormone and insulin-like growth factor-I in postmenopausal women of different ages. J Clin Endocrinol Metab 1991;72:172-8.
8. Weissberger AJ, Ho KKY, Lazarus L. Contrasting effects of oral and transdermal routes of estrogen replacement therapy on 24-h growth hormone (GH) secretion, insulin-like growth factor I, and GH-binding protein in postmenopausal women. J Clin Endocrinol Metab 1991;72:374-81.
9. Frohlander N, Von Schoultz B. Growth hormone and somatomedin C during postmenopausal replacement therapy with oestrogen alone and in combination with an antioestrogen. Maturitas 1988;9:297-302.
10. Riggs LB. Editorial: Tibolone as an alternative to estrogen for the prevention of postmenopausal osteoporosis in selected postmenopausal women. J Clin Endocrinol Metab 1996;81:2417-8.
11. Bjarson NH, Bjarson K, Haarbo, Rosenquist C, Christiansen C. Tibolone: prevention of bone loss in late postmenopausal women. J Clin Endocrinol Metab 1996;81:2419-22.
12. Egarter Ch, Huber J, Leikermoser R, Haidbauer R, Pusch H, Fischl F, Putz M. Tibolone versus conjugated estrogens and sequential progestogen in the treatment of climacteric complaints. Maturitas 1996;23:55-62.
13. Ginsburg J, Prelevic G, Butler D, Okolo S. Clinical experience with tibolone (Livial) over 8 years. Maturitas 1995;21:71-6.
14. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders. 3rd ed. Washington, DC:American Psychiatric Association, 1987.
15. Genazzani AD, Petraglia F, Fabbri G, Monzani A, Montanini V, Genazzani AR. Evidence of luteinizing hormone secretion in hypothalamic amenorrhea associated with weight loss. Fertil Steril 1990;54:222-6.
16. Genazzani AD, Petraglia F, Benatti R, Montanini V, Algeri I, Volpe A, Genazzani AR. Luteinizing hormone (LH) secretory burst duration is independent from LH, prolactin, or gonadal steroid plasma levels in amenorrhei women. J Clin Endocrinol Metab 1991;72:1220-5.
17. Genazzani AD, Petraglia F, Volpogni C, Gastaldi M, Pianazzi F, Montanini V, Genazzani AR. Modulatory role of estrogens and progestins on growth hormone episodic release in women with hypothalamic amenorrhea. Fertil Steril 1993;60:465-70.
18. Daughaday WH, Mariz IK, Blethen SL. Inhibition of access of bound somatomedin to membrane receptor and immunobinding sites - a comparison of radioreceptor and radioimmunoassay of somatomedin in native and acid-ethanol extracted serum. J Clin Endocrinol Metab 1980;51:781-5.
19. Oerter KE, Guardabasso V, Rodbard D. Detection and characterization of peaks and estimation of instantaneous secretory rate for episodic pulsatile hormone secretion. Comput Biomed Res 1986;19:170-91.
20. Genazzani AD. Application of peak-detection programs to clinical data. In: Guardabasso V, Rodbard D, Forti G, editors. Computers in Endocrinology: Recent Advances. New York:Raven 1990:71-82.
21. Genazzani AD, Rodbard D. Evaluation of methods for detection of pulsatile hormone secretion: sensitivity vs. specificity. Acta Endocrinol (Copenhagen) 1991;124: 295306.
22. Faria ACS, Bekenstein LW, Booth RA, Vaccaro VA, Asplin CM, Veldhuis JD, Thorner MO, Evans WS. Pulsatile growth hormone in normal women during the menstrual cycle. Clin Endocrinol 1992;36:591-6.
23. Bellantoni MF. Vittone J, Campfield AT, Bass KM, Harman SM, Blackman MR. Effects of oral versus transdermal estrogen on the growth hormone/insulin-like growth factor I axis in younger an older postmenopausal women: a clinical research center study. J Clin Endocrinol Metab 1996;81:2848-53.
24. Mercuri N, Petraglia F, Genazzani AD, Amato F, Maietta-Latessa A, De Leo V, Nappi C, Genazzani AR. Hormonal treatments modulate plasma growth-hormone, gonadotropin and osteocalcin levels in postmenopausal women. Maturitas 1993;17:51-62.
25. Genazzani AR, Petraglia F, Facchinetti F, Grasso A, Alessandrini G, Volpe A. Steroid replacement treatment increases beta-endorphin and beta-lipotropin plasma levels in postmenopausal women. Gynecol Obstet Invest 1988;26:153-9.
26. Volpe A, Facchinetti F, Grasso A, Petraglia F, Campanini D, Genazzani AR. Benefits and risks of different hormonal replacement therapies in post-menopausal women. Maturitas 1986;8:327-34.