Xq28 and lupus: IRAK1 or MECP2?

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 24, 2009, Pages

  Sawalha, Amr H ^a,b,c  

^a UNIVERSITY OF OKLAHOMA COLLEGE OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; METHYL CPG BINDING PROTEIN 2;

CHROMOSOME POLYMORPHISM; CHROMOSOME XQ; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; HAPLOTYPE; HUMAN; LETTER; LOSS OF FUNCTION MUTATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SYSTEMIC LUPUS ERYTHEMATOSUS;

ANIMALS; CHROMOSOMES, HUMAN, X; DISEASE MODELS, ANIMAL; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LUPUS ERYTHEMATOSUS, SYSTEMIC; METHYL-CPG-BINDING PROTEIN 2; MICE; POLYMORPHISM, GENETIC;

EID: 67649844335     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0904068106     Document Type: Letter

References (4)

1. Sawalha AH, et al. (2008) Common variants within MECP2 confer risk of systemic lupus erythematosus. PLoS ONE 3:e1727.
2. Jacob CO, et al. (2009) Identification of IRAK1 as a risk gene with critical role in the pathogenesis of systemic lupus erythematosus. Proc Natl Acad Sci USA 106:6256-6261.
3. Chahrour M, et al. (2008) MeCP2, a key contributor to neurological disease, activates and represses transcription. Science 320:1224-1229. (Pubitemid 351929512)
4. Urdinguio RG, et al. (2008) Mecp2-null mice provide new neuronal targets for Rett syndrome. PLoS ONE 3:e3669.