Determination of oleanolic acid and ursolic acid in Oldenlandia diffusa and its substitute using high performance liquid chromatography

Journal of Food and Drug Analysis

Volumn 17, Issue 2, 2009, Pages 69-77

  Liang, Zhitao ^a   Jiang, Zhihong ^a   Fong, David Wangfun ^a   Zhao, Zhongzhen ^a  

^a HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

HPLC; Oldenlandia corymbosa; Oldenlandia diffusa; Oleanolic acid; Ursolic acid

Indexed keywords

OLEANOLIC ACID; URSOLIC ACID;

ARTICLE; CHEMICAL COMPOSITION; DRUG DETERMINATION; DRUG ISOLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; OLDENLANDIA; OLDENLANDIA CORYMBOSA; OLDENLANDIA DIFFUSA; PLANT IDENTIFICATION; QUALITY CONTROL; SEPARATION TECHNIQUE; SPECIES IDENTIFICATION;

HEDYOTIS DIFFUSA; OLDENLANDIA CORYMBOSA;

EID: 67649797798     PISSN: 10219498     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Xu, G. J., Xu, L. S. and Wang, Z. T. 1997. Species Systematization and Quality Evaluation of Commonly Used Chinese Traditional Drugs, South-China Edition, p. 658. Fujian Science and Technology Press. Fuzhou, China.
2. Pharmacopoeia of China, 2005. Appendix p. 22. Chemical Industry Publishing House. Beijing, China.
3. Zhao, Z. Z. and Li, T. Y. S. 2008. Illustrated 100 Group Easily Confused Chinese Materia Medica. Traditional Chinese version. p. 168. Wan Li Book Co. Ltd. Hong Kong, China.
4. Yang, J. J. and Lin, C. C. 1997. The possible use of Peh-Hue-Juwa-Chi-Cao as an antitumor agent and radioprotector after therapeutic irradiation. Phytothe. Res. 11: 6-10.
5. Gbaguidi, F., Accrombessi, G., Moudachirou, M. and Quetin-Leclercq, J. 2005. HPLC quantification of two isomeric triterpenic acid isolated from Mitracarpus scaber and antimicrobial activity on Dermatophilus congolensis. J. Pharm. Biomed. Anal. 39: 990-995. (Pubitemid 41441728)
6. Liu, H., Shi, Y., Wang, D., Yang, G., Yu, A. and Zhang, H. 2003. MECC determination of oleanolic acid and ursolic acid isomers in Ligustrum lucidum Ait. J. Pharm. Biomed. Anal. 32: 479-485.
7. Chen, J. H., Xia, Z. H. and Tan, R. X. 2003. High-performance liquid chromatographic analysis of bioactive triterpenes in Perilla frutescens. J. Pharm. Biomed. Anal. 32: 1175-1179. (Pubitemid 36939124)
8. Cui, T., Li, J. Z., Kayahara, H., Ma, L., Wu, L. X. and Nakamura K. 2006. Quantification of the polyphenols and triterpene acids in Chinese hawthorn fruit by high-performance liquid chromatography. J. Agric. Food Chem. 54: 4574-4581.
9. Xie, Y., Hang, T. J., Cheng, Z., Zhang, Z. X. and An D. K. 2001. PLC determination of oleanolic acid and ursolic acid in Chinese medicinal herbs. Chin. J. Chin. Mat. Med. 26: 615-616.
10. Liu, J., Liu, Y., Mao, Q. and Klaassen, C. D. 1994. The effects of 10 triterpenoid compounds on experimental liver injury in mice. Fundam. Appl. Toxicol. 22: 34-40.
11. Liu, J. 1997. Pharmacology of oleanolic acid and ursolic acid. J. Ethnopharmacol. 49: 57-68. (Pubitemid 26010740)
12. Tokuda, H., Ohigashi, H., Koshimizu, K. and Ito, Y. 1986. Inhibitory effects of ursolic and oleanolic acid on skin tumor promotion by 12-O-tetradecanoylphorbol -13-acetate. Cancer Lett. 33: 279-285. (Pubitemid 17208491)
13. Hsu, H. Y., Yang, J. J. and Lin, C. C. 1997. Effects of oleanolic acid and ursolic acid on inhibiting tumor growth and enhancing the recovery of hematopoietic system postirradiation in mice. Cancer Lett. 111: 7-13. (Pubitemid 27068212)
14. Aparecida Resende, F., de Andrade Barcala, C. A., da Silva Faria, M. C. and Kato, F. H. 2006. Antimutagenicity of ursolic acid and oleanolic acid against doxorubicin-induced clastogenesis in Balb/c mice. Life Sci. 79: 1268-1273.
15. Ovesna, Z., Kozics, K. and Slamenova, D. 2006. Protective effects of ursolic acid and oleanolic acid in leukemic cells. Mutat. Res. 600: 131-137.
16. Zhou, C., Wang, L. and Feng, X. Y. 2002. Comparison of the contents of oleanolic acid and ursolic acid in Hedyotis diffusa Willd. and H. corymbosa (L.) Lam. Zhongyaocai 25: 313-314.
17. Luo, X. G., Jiang, L. L. and Zhao, S. J. 2004. Simultaneous determination of oleanolic acid and ursolic acid in Hedyotis diffusa with HPLC. China Pharmacy 15: 175-176.
18. Zhang, C. H., Guo, X. J., Li, F., Xue, X. F. and Li, F. M. 2004. HPLC determination of the contents of oleanolic acid and ursolic acid in Hedyotis diffusa Willd. J. Shenyang Pharm. Uni. 21: 358-370.
19. Liao, L. P., Li, S. L. and Li, P. 2005. Simultaneous determination of seven triterpenoids and triterpenoid saponins in Folium llicis Purpureae by high performance liquid chromatography coupled with evaporative light scattering detection. J. Sep. Sci. 28: 2061-2066.
20. Xie, Y., Wu, C. H. and Xie, B. J. 2004. Detection of oleanolic acid and ursolic acid in Crataegus pinnatifida by HPLC-ELSD. Chin. Trad. Herb. Drugs. 35: 1417-1478.
21. Tang, L. Q., Liu, S., Li, C. and Chen, L. M. 2004. Determination of oleanolic acid and ursolic acid in Eriobotrya japonica (Thumb.) Lindl extract by HPLC. Zhongguo Yiyuan Yaoxue Zazhi 24: 725-726.
22. Luo, X. Q., Guo, X. Y. and Yu, X. W. 2004. Determination of ursolic acid and oleanolic acid in leaf of Eriobotrya japonica by RP-HPLC. Chin. Wild Plant Res. 23: 50-51.
23. Xiang, Y. Y. and Yang, G. 2004. Contents determination of oleanolic acid and ursolic acid in some traditional Chinese medicinal herbs. Zhongguo Yiyuan Yaoxue Zazhi 24: 316-317.
24. Zhao, Y. X. and Li, M. L. 2004. HPLC-ELSD determination of oleanolic acid and ursolic acid in Chinese herbal medicine and Chinese patent medicines. Chin. J. Pharm. Anal. 24: 167-170.
25. Xu, D. R., Ding, J. and Wang, Z. T. 2002. Determination of oleanolic acid and ursolic acid in fructus corni and Zhibaidihuang pill by HPLC. Chin. Trad. Herb. Drugs. 33: 996-997.
26. Li, T., Hao, W. C., Xu, C. G. and Ma, P. F. 2005. Investigation of oleanolic acid and ursolic acid in Fructus Ligustri Lucidi of different producing area by HPLC-ELSD. J. Chin. Med. Mat. 28: 391-393.
27. Xu, S., Deng, X. K., Chen, B., Xu, C. F. and Chen, Q. 2006. Determination of oleanolic acid and ursolic acid in Verbena officinalis L. using RP-HPLC. Acta Universitatis Medicinalis Nanjing 26: 165-168.
28. Yan, H. L., Zhao, L. H., Zhu, D. N. and Ding, L. 1999. Determination of oleanolic acid and ursolic acid in Spica Prunellae by derivative GC method. Zhongguo Zhongyao Zazhi 24: 744-745.
29. Zhang, G., Qi, Y., Lou, Z., Liu, C., Wu, X. and Chai, Y. 2005. Determination of oleanolic acid and ursolic acid in cornel by cyclodextrin-modified micellar electrokinetic chromatography. Biomed. Chromatogr. 19: 529-532.
30. Liu, H., Shi, Y., Wang, D., Yang, G., Yu, A. and Zhang, H. MECC determination of oleanolic acid and ursolic acid isomers in Ligustrum lucidum Ait. J. Pharm. Biomed. Anal. 32: 479-485.
31. Qi, S., Ding, L., Tian, K., Chen, X. and Hu, Z. 2006. Novel and simple nonaqueous capillary electrophoresis separation and determination bioactive triterpenes in Chinese herbs. J. Pharm. Biomed. Anal. 40: 35-41.
32. Liang, Z. T., Jiang, Z. H., Leung K. S. Y. and Zhao, Z. Z. 2006. Determination of iridoid glucosides for quality assessment of herba Oldenlandiae by high-performance liquid chromatography. Chem. Pharm. Bull. 54: 1131-1137.