-
1
-
-
41349099104
-
Cancer statistics, 2008
-
Jemal A., Siegel R., Ward E., Hao Y., Xu J., Murray T., et al. Cancer statistics, 2008. CA Cancer J Clin 58 (2008) 71-96
-
(2008)
CA Cancer J Clin
, vol.58
, pp. 71-96
-
-
Jemal, A.1
Siegel, R.2
Ward, E.3
Hao, Y.4
Xu, J.5
Murray, T.6
-
2
-
-
0037050355
-
Lung cancer-time to move on from chemotherapy
-
Carney D.N. Lung cancer-time to move on from chemotherapy. N Engl J Med 346 (2002) 126-128
-
(2002)
N Engl J Med
, vol.346
, pp. 126-128
-
-
Carney, D.N.1
-
3
-
-
0036869934
-
Current therapeutic approaches in lung cancer
-
Bunn Jr. P.A. Current therapeutic approaches in lung cancer. Clin Lung Cancer 4 Suppl. 1 (2002) S4
-
(2002)
Clin Lung Cancer
, vol.4
, Issue.SUPPL. 1
-
-
Bunn Jr., P.A.1
-
4
-
-
19844362355
-
Epidermal growth factor receptor inhibitors in the treatment of non-small-cell lung cancer
-
Giaccone G. Epidermal growth factor receptor inhibitors in the treatment of non-small-cell lung cancer. J Clin Oncol 23 (2005) 3235-3242
-
(2005)
J Clin Oncol
, vol.23
, pp. 3235-3242
-
-
Giaccone, G.1
-
5
-
-
40849147041
-
EGFR antagonists in cancer treatment
-
Ciardiello F., and Tortora G. EGFR antagonists in cancer treatment. N Engl J Med 358 (2008) 1160-1174
-
(2008)
N Engl J Med
, vol.358
, pp. 1160-1174
-
-
Ciardiello, F.1
Tortora, G.2
-
7
-
-
18244371651
-
Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain
-
Pao W., Miller V.A., Politi K.A., Riely G.J., Somwar R., Zakowski M.F., et al. Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain. PLoS Med 2 (2005) e73
-
(2005)
PLoS Med
, vol.2
-
-
Pao, W.1
Miller, V.A.2
Politi, K.A.3
Riely, G.J.4
Somwar, R.5
Zakowski, M.F.6
-
8
-
-
11344268358
-
Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor
-
Camp E.R., Summy J., Bauer T.W., Liu W., Gallick G.E., and Ellis L.M. Molecular mechanisms of resistance to therapies targeting the epidermal growth factor receptor. Clin Cancer Res 11 (2005) 397-405
-
(2005)
Clin Cancer Res
, vol.11
, pp. 397-405
-
-
Camp, E.R.1
Summy, J.2
Bauer, T.W.3
Liu, W.4
Gallick, G.E.5
Ellis, L.M.6
-
9
-
-
43749107912
-
Acquired resistance to tyrosine kinase inhibitors during cancer therapy
-
Engelman J.A., and Settleman J. Acquired resistance to tyrosine kinase inhibitors during cancer therapy. Curr Opin Genet Dev 18 (2008) 73-79
-
(2008)
Curr Opin Genet Dev
, vol.18
, pp. 73-79
-
-
Engelman, J.A.1
Settleman, J.2
-
10
-
-
0037429737
-
Epidermal growth factor receptor: mechanisms of activation and signalling
-
Jorissen R.N., Walker F., Pouliot N., Garrett T.P., Ward C.W., and Burgess A.W. Epidermal growth factor receptor: mechanisms of activation and signalling. Exp Cell Res 284 (2003) 31-53
-
(2003)
Exp Cell Res
, vol.284
, pp. 31-53
-
-
Jorissen, R.N.1
Walker, F.2
Pouliot, N.3
Garrett, T.P.4
Ward, C.W.5
Burgess, A.W.6
-
11
-
-
14844366111
-
ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines
-
Engelman J.A., Janne P.A., Mermel C., Pearlberg J., Mukohara T., Fleet C., et al. ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines. Proc Natl Acad Sci U S A 102 (2005) 3788-3793
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3788-3793
-
-
Engelman, J.A.1
Janne, P.A.2
Mermel, C.3
Pearlberg, J.4
Mukohara, T.5
Fleet, C.6
-
12
-
-
24944480788
-
The Akt-mTOR tango and its relevance to cancer
-
Hay N. The Akt-mTOR tango and its relevance to cancer. Cancer Cell 8 (2005) 179-183
-
(2005)
Cancer Cell
, vol.8
, pp. 179-183
-
-
Hay, N.1
-
13
-
-
27944467499
-
Resistance to epidermal growth factor receptor-targeted therapy
-
Morgillo F., and Lee H.Y. Resistance to epidermal growth factor receptor-targeted therapy. Drug Resist Update 8 (2005) 298-310
-
(2005)
Drug Resist Update
, vol.8
, pp. 298-310
-
-
Morgillo, F.1
Lee, H.Y.2
-
15
-
-
8844222002
-
Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions
-
Balsara B.R., Pei J., Mitsuuchi Y., Page R., Klein-Szanto A., Wang H., et al. Frequent activation of AKT in non-small cell lung carcinomas and preneoplastic bronchial lesions. Carcinogenesis 25 (2004) 2053-2059
-
(2004)
Carcinogenesis
, vol.25
, pp. 2053-2059
-
-
Balsara, B.R.1
Pei, J.2
Mitsuuchi, Y.3
Page, R.4
Klein-Szanto, A.5
Wang, H.6
-
16
-
-
34547683568
-
Rationale for a phase I trial of erlotinib and the mammalian target of rapamycin inhibitor everolimus (RAD001) for patients with relapsed non small cell lung cancer
-
Johnson B.E., Jackman D., and Janne P.A. Rationale for a phase I trial of erlotinib and the mammalian target of rapamycin inhibitor everolimus (RAD001) for patients with relapsed non small cell lung cancer. Clin Cancer Res 13 (2007) s4628-s4631
-
(2007)
Clin Cancer Res
, vol.13
-
-
Johnson, B.E.1
Jackman, D.2
Janne, P.A.3
-
17
-
-
54949104315
-
A phase II study of RAD001 (R) (everolimus) monotherapy in patients with advanced non-small cell lung cancer (NSCLC) failing prior platinum-based chemotherapy (C) or prior C and EGFR inhibitors (EGFR-I)
-
Papadimitrakopoulou V., Soria J.C., Douillard J.Y., Giaccone G., Wolf J., Crino L., et al. A phase II study of RAD001 (R) (everolimus) monotherapy in patients with advanced non-small cell lung cancer (NSCLC) failing prior platinum-based chemotherapy (C) or prior C and EGFR inhibitors (EGFR-I). J Clin Oncol 25 18 Suppl. (2007) 406s
-
(2007)
J Clin Oncol
, vol.25
, Issue.18 SUPPL
-
-
Papadimitrakopoulou, V.1
Soria, J.C.2
Douillard, J.Y.3
Giaccone, G.4
Wolf, J.5
Crino, L.6
-
18
-
-
40349106029
-
The potential role of mTOR inhibitors in non-small cell lung cancer
-
Gridelli C., Maione P., and Rossi A. The potential role of mTOR inhibitors in non-small cell lung cancer. Oncologist 13 (2008) 139-147
-
(2008)
Oncologist
, vol.13
, pp. 139-147
-
-
Gridelli, C.1
Maione, P.2
Rossi, A.3
-
19
-
-
34547133008
-
Phase 1 trial of everolimus and gefitinib in patients with advanced nonsmall-cell lung cancer
-
Milton D.T., Riely G.J., Azzoli C.G., Gomez J.E., Heelan R.T., Kris M.G., et al. Phase 1 trial of everolimus and gefitinib in patients with advanced nonsmall-cell lung cancer. Cancer 110 (2007) 599-605
-
(2007)
Cancer
, vol.110
, pp. 599-605
-
-
Milton, D.T.1
Riely, G.J.2
Azzoli, C.G.3
Gomez, J.E.4
Heelan, R.T.5
Kris, M.G.6
-
20
-
-
34548853993
-
Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus
-
Riely G.J., Kris M.G., Zhao B., Akhurst T., Milton D.T., Moore E., et al. Prospective assessment of discontinuation and reinitiation of erlotinib or gefitinib in patients with acquired resistance to erlotinib or gefitinib followed by the addition of everolimus. Clin Cancer Res 13 (2007) 5150-5155
-
(2007)
Clin Cancer Res
, vol.13
, pp. 5150-5155
-
-
Riely, G.J.1
Kris, M.G.2
Zhao, B.3
Akhurst, T.4
Milton, D.T.5
Moore, E.6
-
21
-
-
33745145030
-
5-benzylidene-hydantoins as new EGFR inhibitors with antiproliferative activity
-
Carmi C., Cavazzoni A., Zuliani V., Lodola A., Bordi F., Plazzi P.V., et al. 5-benzylidene-hydantoins as new EGFR inhibitors with antiproliferative activity. Bioorg Med Chem Lett 16 (2006) 4021-4025
-
(2006)
Bioorg Med Chem Lett
, vol.16
, pp. 4021-4025
-
-
Carmi, C.1
Cavazzoni, A.2
Zuliani, V.3
Lodola, A.4
Bordi, F.5
Plazzi, P.V.6
-
22
-
-
9144272760
-
Dose-dependent effect of FHIT-inducible expression in Calu-1 lung cancer cell line
-
Cavazzoni A., Petronini P.G., Galetti M., Roz L., Andriani F., Carbognani P., et al. Dose-dependent effect of FHIT-inducible expression in Calu-1 lung cancer cell line. Oncogene 23 (2004) 8439-8446
-
(2004)
Oncogene
, vol.23
, pp. 8439-8446
-
-
Cavazzoni, A.1
Petronini, P.G.2
Galetti, M.3
Roz, L.4
Andriani, F.5
Carbognani, P.6
-
23
-
-
0022880936
-
Determination of cell number in monolayer cultures
-
Gillies R.J., Didier N., and Denton M. Determination of cell number in monolayer cultures. Anal Biochem 159 (1986) 109-113
-
(1986)
Anal Biochem
, vol.159
, pp. 109-113
-
-
Gillies, R.J.1
Didier, N.2
Denton, M.3
-
24
-
-
39749189407
-
Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines
-
Cavazzoni A., Alfieri R.R., Carmi C., Zuliani V., Galetti M., Fumarola C., et al. Dual mechanisms of action of the 5-benzylidene-hydantoin UPR1024 on lung cancer cell lines. Mol Cancer Ther 7 (2008) 361-370
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 361-370
-
-
Cavazzoni, A.1
Alfieri, R.R.2
Carmi, C.3
Zuliani, V.4
Galetti, M.5
Fumarola, C.6
-
25
-
-
0037976885
-
Models of neurotoxicity: extrapolation of benchmark doses in vitro
-
Goldoni M., Vettori M.V., Alinovi R., Caglieri A., Ceccatelli S., and Mutti A. Models of neurotoxicity: extrapolation of benchmark doses in vitro. Risk Anal 23 (2003) 505-514
-
(2003)
Risk Anal
, vol.23
, pp. 505-514
-
-
Goldoni, M.1
Vettori, M.V.2
Alinovi, R.3
Caglieri, A.4
Ceccatelli, S.5
Mutti, A.6
-
26
-
-
34247177620
-
A mathematical approach to study combined effects of toxicants in vitro: evaluation of the Bliss independence criterion and the Loewe additivity model
-
Goldoni M., and Johansson C. A mathematical approach to study combined effects of toxicants in vitro: evaluation of the Bliss independence criterion and the Loewe additivity model. Toxicol In Vitro 21 (2007) 759-769
-
(2007)
Toxicol In Vitro
, vol.21
, pp. 759-769
-
-
Goldoni, M.1
Johansson, C.2
-
27
-
-
58949098405
-
Epidermal growth factor receptor intron-1 polymorphism predicts gefitinib outcome in advanced non-small cell lung cancer
-
Tiseo M., Capelletti M., De Palma G., Franciosi V., Cavazzoni A., Mozzoni P., et al. Epidermal growth factor receptor intron-1 polymorphism predicts gefitinib outcome in advanced non-small cell lung cancer. J Thorac Oncol 3 (2008) 1104-1111
-
(2008)
J Thorac Oncol
, vol.3
, pp. 1104-1111
-
-
Tiseo, M.1
Capelletti, M.2
De Palma, G.3
Franciosi, V.4
Cavazzoni, A.5
Mozzoni, P.6
-
28
-
-
33745059265
-
Chemotherapy-induced epidermal growth factor receptor activation determines response to combined gefitinib/chemotherapy treatment in non-small cell lung cancer cells
-
Van Schaeybroeck S., Kyula J., Kelly D.M., Karaiskou-McCaul A., Stokesberry S.A., Van Cutsem E., et al. Chemotherapy-induced epidermal growth factor receptor activation determines response to combined gefitinib/chemotherapy treatment in non-small cell lung cancer cells. Mol Cancer Ther 5 (2006) 1154-1165
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 1154-1165
-
-
Van Schaeybroeck, S.1
Kyula, J.2
Kelly, D.M.3
Karaiskou-McCaul, A.4
Stokesberry, S.A.5
Van Cutsem, E.6
-
29
-
-
37549001026
-
Proapoptotic BH3-only BCL-2 family protein BIM connects death signaling from epidermal growth factor receptor inhibition to the mitochondrion
-
Deng J., Shimamura T., Perera S., Carlson N.E., Cai D., Shapiro G.I., et al. Proapoptotic BH3-only BCL-2 family protein BIM connects death signaling from epidermal growth factor receptor inhibition to the mitochondrion. Cancer Res 67 (2007) 11867-11875
-
(2007)
Cancer Res
, vol.67
, pp. 11867-11875
-
-
Deng, J.1
Shimamura, T.2
Perera, S.3
Carlson, N.E.4
Cai, D.5
Shapiro, G.I.6
-
30
-
-
38649119730
-
Signaling networks assembled by oncogenic EGFR and c-Met
-
Guo A., Villen J., Kornhauser J., Lee K.A., Stokes M.P., Rikova K., et al. Signaling networks assembled by oncogenic EGFR and c-Met. Proc Natl Acad Sci U S A 105 (2008) 692-697
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 692-697
-
-
Guo, A.1
Villen, J.2
Kornhauser, J.3
Lee, K.A.4
Stokes, M.P.5
Rikova, K.6
-
31
-
-
27944444486
-
Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells
-
Janmaat M.L., Rodriguez J.A., Gallegos-Ruiz M., Kruyt F.A., and Giaccone G. Enhanced cytotoxicity induced by gefitinib and specific inhibitors of the Ras or phosphatidyl inositol-3 kinase pathways in non-small cell lung cancer cells. Int J Cancer 118 (2006) 209-214
-
(2006)
Int J Cancer
, vol.118
, pp. 209-214
-
-
Janmaat, M.L.1
Rodriguez, J.A.2
Gallegos-Ruiz, M.3
Kruyt, F.A.4
Giaccone, G.5
-
32
-
-
40049099220
-
The T790 M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP
-
Yun C.H., Mengwasser K.E., Toms A.V., Woo M.S., Greulich H., Wong K.K., et al. The T790 M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP. Proc Natl Acad Sci U S A 105 (2008) 2070-2075
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 2070-2075
-
-
Yun, C.H.1
Mengwasser, K.E.2
Toms, A.V.3
Woo, M.S.4
Greulich, H.5
Wong, K.K.6
-
33
-
-
3843116718
-
Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib ('Iressa', ZD1839) in non-small-cell lung cancer
-
Parra H.S., Cavina R., Latteri F., Zucali P.A., Campagnoli E., Morenghi E., et al. Analysis of epidermal growth factor receptor expression as a predictive factor for response to gefitinib ('Iressa', ZD1839) in non-small-cell lung cancer. Br J Cancer 91 (2004) 208-212
-
(2004)
Br J Cancer
, vol.91
, pp. 208-212
-
-
Parra, H.S.1
Cavina, R.2
Latteri, F.3
Zucali, P.A.4
Campagnoli, E.5
Morenghi, E.6
-
34
-
-
2642570481
-
Sensitivity to gefitinib (Iressa, ZD1839) in non-small cell lung cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor/extracellular signal-regulated kinase 1/2 and EGF receptor/Akt pathway for proliferation
-
Ono M., Hirata A., Kometani T., Miyagawa M., Ueda S., Kinoshita H., et al. Sensitivity to gefitinib (Iressa, ZD1839) in non-small cell lung cancer cell lines correlates with dependence on the epidermal growth factor (EGF) receptor/extracellular signal-regulated kinase 1/2 and EGF receptor/Akt pathway for proliferation. Mol Cancer Ther 3 (2004) 465-472
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 465-472
-
-
Ono, M.1
Hirata, A.2
Kometani, T.3
Miyagawa, M.4
Ueda, S.5
Kinoshita, H.6
-
35
-
-
2342624080
-
EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy
-
Paez J.G., Janne P.A., Lee J.C., Tracy S., Greulich H., Gabriel S., et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science 304 (2004) 1497-1500
-
(2004)
Science
, vol.304
, pp. 1497-1500
-
-
Paez, J.G.1
Janne, P.A.2
Lee, J.C.3
Tracy, S.4
Greulich, H.5
Gabriel, S.6
-
36
-
-
4143066760
-
Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways
-
Sordella R., Bell D.W., Haber D.A., and Settleman J. Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways. Science 305 (2004) 1163-1167
-
(2004)
Science
, vol.305
, pp. 1163-1167
-
-
Sordella, R.1
Bell, D.W.2
Haber, D.A.3
Settleman, J.4
-
37
-
-
9144233506
-
Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells
-
Boulay A., Zumstein-Mecker S., Stephan C., Beuvink I., Zilbermann F., Haller R., et al. Antitumor efficacy of intermittent treatment schedules with the rapamycin derivative RAD001 correlates with prolonged inactivation of ribosomal protein S6 kinase 1 in peripheral blood mononuclear cells. Cancer Res 64 (2004) 252-261
-
(2004)
Cancer Res
, vol.64
, pp. 252-261
-
-
Boulay, A.1
Zumstein-Mecker, S.2
Stephan, C.3
Beuvink, I.4
Zilbermann, F.5
Haller, R.6
-
38
-
-
1642576127
-
Rapamycin inhibits the growth and metastatic progression of non-small cell lung cancer
-
Boffa D.J., Luan F., Thomas D., Yang H., Sharma V.K., Lagman M., et al. Rapamycin inhibits the growth and metastatic progression of non-small cell lung cancer. Clin Cancer Res 10 (2004) 293-300
-
(2004)
Clin Cancer Res
, vol.10
, pp. 293-300
-
-
Boffa, D.J.1
Luan, F.2
Thomas, D.3
Yang, H.4
Sharma, V.K.5
Lagman, M.6
-
39
-
-
23844438209
-
Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition
-
Sun S.Y., Rosenberg L.M., Wang X., Zhou Z., Yue P., Fu H., et al. Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition. Cancer Res 65 (2005) 7052-7058
-
(2005)
Cancer Res
, vol.65
, pp. 7052-7058
-
-
Sun, S.Y.1
Rosenberg, L.M.2
Wang, X.3
Zhou, Z.4
Yue, P.5
Fu, H.6
-
40
-
-
34547130295
-
RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model
-
Mabuchi S., Altomare D.A., Cheung M., Zhang L., Poulikakos P.I., Hensley H.H., et al. RAD001 inhibits human ovarian cancer cell proliferation, enhances cisplatin-induced apoptosis, and prolongs survival in an ovarian cancer model. Clin Cancer Res 13 (2007) 4261-4270
-
(2007)
Clin Cancer Res
, vol.13
, pp. 4261-4270
-
-
Mabuchi, S.1
Altomare, D.A.2
Cheung, M.3
Zhang, L.4
Poulikakos, P.I.5
Hensley, H.H.6
-
41
-
-
1042267229
-
Determinants of rapamycin sensitivity in breast cancer cells
-
Noh W.C., Mondesire W.H., Peng J., Jian W., Zhang H., Dong J., et al. Determinants of rapamycin sensitivity in breast cancer cells. Clin Cancer Res 10 (2004) 1013-1023
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1013-1023
-
-
Noh, W.C.1
Mondesire, W.H.2
Peng, J.3
Jian, W.4
Zhang, H.5
Dong, J.6
-
42
-
-
32944457518
-
mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt
-
O'Reilly K.E., Rojo F., She Q.B., Solit D., Mills G.B., Smith D., et al. mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt. Cancer Res 66 (2006) 1500-1508
-
(2006)
Cancer Res
, vol.66
, pp. 1500-1508
-
-
O'Reilly, K.E.1
Rojo, F.2
She, Q.B.3
Solit, D.4
Mills, G.B.5
Smith, D.6
-
43
-
-
33845227643
-
Rapamycin synergizes with the epidermal growth factor receptor inhibitor erlotinib in non-small-cell lung, pancreatic, colon, and breast tumors
-
Buck E., Eyzaguirre A., Brown E., Petti F., McCormack S., Haley J.D., et al. Rapamycin synergizes with the epidermal growth factor receptor inhibitor erlotinib in non-small-cell lung, pancreatic, colon, and breast tumors. Mol Cancer Ther 5 (2006) 2676-2684
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 2676-2684
-
-
Buck, E.1
Eyzaguirre, A.2
Brown, E.3
Petti, F.4
McCormack, S.5
Haley, J.D.6
-
44
-
-
40349108627
-
Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs
-
Bianco R., Garofalo S., Rosa R., Damiano V., Gelardi T., Daniele G., et al. Inhibition of mTOR pathway by everolimus cooperates with EGFR inhibitors in human tumours sensitive and resistant to anti-EGFR drugs. Br J Cancer 98 (2008) 923-930
-
(2008)
Br J Cancer
, vol.98
, pp. 923-930
-
-
Bianco, R.1
Garofalo, S.2
Rosa, R.3
Damiano, V.4
Gelardi, T.5
Daniele, G.6
-
45
-
-
38949141134
-
Synergic antiproliferative and antiangiogenic effects of EGFR and mTor inhibitors on pancreatic cancer cells
-
Azzariti A., Porcelli L., Gatti G., Nicolin A., and Paradiso A. Synergic antiproliferative and antiangiogenic effects of EGFR and mTor inhibitors on pancreatic cancer cells. Biochem Pharmacol 75 (2008) 1035-1044
-
(2008)
Biochem Pharmacol
, vol.75
, pp. 1035-1044
-
-
Azzariti, A.1
Porcelli, L.2
Gatti, G.3
Nicolin, A.4
Paradiso, A.5
-
46
-
-
33947422073
-
Dual EGFR and mTOR targeting in squamous cell carcinoma models, and development of early markers of efficacy
-
Jimeno A., Kulesza P., Wheelhouse J., Chan A., Zhang X., Kincaid E., et al. Dual EGFR and mTOR targeting in squamous cell carcinoma models, and development of early markers of efficacy. Br J Cancer 96 (2007) 952-959
-
(2007)
Br J Cancer
, vol.96
, pp. 952-959
-
-
Jimeno, A.1
Kulesza, P.2
Wheelhouse, J.3
Chan, A.4
Zhang, X.5
Kincaid, E.6
-
47
-
-
49849084685
-
Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors
-
Johansson G., Mahller Y.Y., Collins M.H., Kim M.O., Nobukuni T., Perentesis J., et al. Effective in vivo targeting of the mammalian target of rapamycin pathway in malignant peripheral nerve sheath tumors. Mol Cancer Ther 7 (2008) 1237-1245
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1237-1245
-
-
Johansson, G.1
Mahller, Y.Y.2
Collins, M.H.3
Kim, M.O.4
Nobukuni, T.5
Perentesis, J.6
-
48
-
-
40349115320
-
Combined inhibition of mTOR and EGFR with everolimus (RAD001) and gefitinib in patients with non-small cell lung cancer who have smoked cigarettes: a phase II trial
-
Kris M.G., Riely G.J., Azzoli C.G., Heelan R.T., Krug L.M., Pao W., et al. Combined inhibition of mTOR and EGFR with everolimus (RAD001) and gefitinib in patients with non-small cell lung cancer who have smoked cigarettes: a phase II trial. J Clin Oncol 25 18 Suppl. (2007) 403 s
-
(2007)
J Clin Oncol
, vol.25
, Issue.18 SUPPL
-
-
Kris, M.G.1
Riely, G.J.2
Azzoli, C.G.3
Heelan, R.T.4
Krug, L.M.5
Pao, W.6
-
49
-
-
12344255903
-
Ki-67 expression and patients survival in lung cancer: systematic review of the literature with meta-analysis
-
Martin B., Paesmans M., Mascaux C., Berghmans T., Lothaire P., Meert A.P., et al. Ki-67 expression and patients survival in lung cancer: systematic review of the literature with meta-analysis. Br J Cancer 91 (2004) 2018-2025
-
(2004)
Br J Cancer
, vol.91
, pp. 2018-2025
-
-
Martin, B.1
Paesmans, M.2
Mascaux, C.3
Berghmans, T.4
Lothaire, P.5
Meert, A.P.6
-
50
-
-
58149132007
-
Relationship between non-small cell lung cancer FDG uptake at PET, tumor histology, and Ki-67 proliferation index
-
Vesselle H., Salskov A., Turcotte E., Wiens L., Schmidt R., Jordan C.D., et al. Relationship between non-small cell lung cancer FDG uptake at PET, tumor histology, and Ki-67 proliferation index. J Thorac Oncol 3 (2008) 971-978
-
(2008)
J Thorac Oncol
, vol.3
, pp. 971-978
-
-
Vesselle, H.1
Salskov, A.2
Turcotte, E.3
Wiens, L.4
Schmidt, R.5
Jordan, C.D.6
-
51
-
-
38649097511
-
Usefulness of FDG-PET for early prediction of the response to gefitinib in non-small cell lung cancer
-
Sunaga N., Oriuchi N., Kaira K., Yanagitani N., Tomizawa Y., Hisada T., et al. Usefulness of FDG-PET for early prediction of the response to gefitinib in non-small cell lung cancer. Lung Cancer 59 (2008) 203-210
-
(2008)
Lung Cancer
, vol.59
, pp. 203-210
-
-
Sunaga, N.1
Oriuchi, N.2
Kaira, K.3
Yanagitani, N.4
Tomizawa, Y.5
Hisada, T.6
|