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Volumn 37, Issue 7, 2009, Pages 2235-2241

Protective effects of adenosine A2A receptor agonist in ventilator-induced lung injury in rats

Author keywords

Acute Respiratory distress syndrome; Inflammation; Neutrophils

Indexed keywords

2 [4 (2 CARBOXYETHYL)PHENETHYLAMINO]ADENOSINE 5' (N ETHYLCARBOXAMIDE); GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 6; PLACEBO; TUMOR NECROSIS FACTOR ALPHA; ADENOSINE; ADENOSINE A2A RECEPTOR; CYTOKINE; DRUG DERIVATIVE; PHENETHYLAMINE DERIVATIVE;

EID: 67649764045     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e3181a55273     Document Type: Article
Times cited : (17)

References (43)
  • 1
    • 33847782311 scopus 로고    scopus 로고
    • A neutrophil elastase inhibitor, sivelestat, ameliorates lung injury after hemorrhagic shock in rats
    • Toda Y, Takahashi T, Maeshima K, et al: A neutrophil elastase inhibitor, sivelestat, ameliorates lung injury after hemorrhagic shock in rats. Int J Mol Med 2007; 19:237-243
    • (2007) Int J Mol Med , vol.19 , pp. 237-243
    • Toda, Y.1    Takahashi, T.2    Maeshima, K.3
  • 2
    • 0038678064 scopus 로고    scopus 로고
    • Modeling the two-hit hypothesis for evaluating strategies to prevent organ injury after shock/resuscitation
    • Rotstein OD: Modeling the two-hit hypothesis for evaluating strategies to prevent organ injury after shock/resuscitation. J Trauma 2003; 54:203-206
    • (2003) J Trauma , vol.54 , pp. 203-206
    • Rotstein, O.D.1
  • 3
    • 0041318997 scopus 로고    scopus 로고
    • Differential local and systemic tumor necrosis factor-alpha responses to a second hit of lipopolysaccharide after hemorrhagic shock
    • Schulman AM, Claridge JA, Ghezel-Ayagh A, et al: Differential local and systemic tumor necrosis factor-alpha responses to a second hit of lipopolysaccharide after hemorrhagic shock. J Trauma 2003; 55:298-307
    • (2003) J Trauma , vol.55 , pp. 298-307
    • Schulman, A.M.1    Claridge, J.A.2    Ghezel-Ayagh, A.3
  • 4
    • 33745756536 scopus 로고    scopus 로고
    • Ischemia and reperfusion increases susceptibility to ventilator-induced lung injury in rats
    • Crimi E, Zhang H, Han RN, et al: Ischemia and reperfusion increases susceptibility to ventilator-induced lung injury in rats. Am J Respir Crit Care Med 2006; 174:178-186
    • (2006) Am J Respir Crit Care Med , vol.174 , pp. 178-186
    • Crimi, E.1    Zhang, H.2    Han, R.N.3
  • 5
    • 39049102441 scopus 로고    scopus 로고
    • Mechanical ventilation and hemorrhagic shock-resuscitation interact to increase inflammatory cytokine release in rats
    • Bouadma L, Dreyfuss D, Ricard JD, et al: Mechanical ventilation and hemorrhagic shock-resuscitation interact to increase inflammatory cytokine release in rats. Crit Care Med 2007; 35:2601-2606
    • (2007) Crit Care Med , vol.35 , pp. 2601-2606
    • Bouadma, L.1    Dreyfuss, D.2    Ricard, J.D.3
  • 6
    • 42449140622 scopus 로고    scopus 로고
    • Pharmacological modulation of adenosine system: Novel options for treatment of inflammatory bowel diseases
    • Antonioli L, Fornai M, Colucci R, et al: Pharmacological modulation of adenosine system: Novel options for treatment of inflammatory bowel diseases. Inflamm Bowel Dis 2008; 14:566-574
    • (2008) Inflamm Bowel Dis , vol.14 , pp. 566-574
    • Antonioli, L.1    Fornai, M.2    Colucci, R.3
  • 7
    • 0142170014 scopus 로고    scopus 로고
    • Acute adenosinergic cardioprotection in ischemicreperfused hearts
    • Headrick JP, Hack B, Ashton KJ: Acute adenosinergic cardioprotection in ischemicreperfused hearts. Am J Physiol Heart Circ Physiol 2003; 285:1797-1818
    • (2003) Am J Physiol Heart Circ Physiol , vol.285 , pp. 1797-1818
    • Headrick, J.P.1    Hack, B.2    Ashton, K.J.3
  • 8
    • 0035040532 scopus 로고    scopus 로고
    • Molecular approach to adenosine receptors: Receptor-mediated mechanisms of tissue protection
    • Linden J: Molecular approach to adenosine receptors: Receptor-mediated mechanisms of tissue protection. Annu Rev Pharmacol Toxicol 2001; 41:775-787
    • (2001) Annu Rev Pharmacol Toxicol , vol.41 , pp. 775-787
    • Linden, J.1
  • 9
    • 34250770500 scopus 로고    scopus 로고
    • Adenosine, an endogenous distress signal, modulates tissue damage and repair
    • Fredholm BB: Adenosine, an endogenous distress signal, modulates tissue damage and repair. Cell Death Differ 2007; 14:1315-1323
    • (2007) Cell Death Differ , vol.14 , pp. 1315-1323
    • Fredholm, B.B.1
  • 10
    • 33845720371 scopus 로고    scopus 로고
    • Effects of adenosine on functions of polymorphonuclear leukocytes from patients with septic shock
    • Kaufmann I, Hoelzl A, Schliephake F, et al: Effects of adenosine on functions of polymorphonuclear leukocytes from patients with septic shock. Shock 2007; 27:25-31
    • (2007) Shock , vol.27 , pp. 25-31
    • Kaufmann, I.1    Hoelzl, A.2    Schliephake, F.3
  • 11
    • 0038143146 scopus 로고    scopus 로고
    • Pharmacology of adenosine A2A receptors and therapeutic applications
    • Fredholm BB, Cunha RA, Svenningsson P: Pharmacology of adenosine A2A receptors and therapeutic applications. Curr Top Med Chem 2003; 3:413-426
    • (2003) Curr Top Med Chem , vol.3 , pp. 413-426
    • Fredholm, B.B.1    Cunha, R.A.2    Svenningsson, P.3
  • 12
    • 33645834979 scopus 로고    scopus 로고
    • Adenosine A2A receptor activation reduces lung injury in trauma/hemorrhagic shock
    • Haskó G, Xu DZ, Lu Q, et al: Adenosine A2A receptor activation reduces lung injury in trauma/hemorrhagic shock. Crit Care Med 2006; 34:1119-1125
    • (2006) Crit Care Med , vol.34 , pp. 1119-1125
    • Haskó, G.1    Xu, D.Z.2    Lu, Q.3
  • 13
    • 33749330051 scopus 로고    scopus 로고
    • Nucleotides induce IL-6 release from human airway epithelia via P2Y2 and p38 MAPK-dependent pathways
    • Douillet CD, Robinson WP III, Milano PM, et al: Nucleotides induce IL-6 release from human airway epithelia via P2Y2 and p38 MAPK-dependent pathways. Am J Physiol Lung Cell Mol Physiol 2006; 291:L734-L746
    • (2006) Am J Physiol Lung Cell Mol Physiol , vol.291
    • Douillet, C.D.1    Robinson III, W.P.2    Milano, P.M.3
  • 14
    • 34250155915 scopus 로고    scopus 로고
    • Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury
    • Eckle T, Füllbier L, Wehrmann M, et al: Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury. J Immunol 2007; 178:8127-8137
    • (2007) J Immunol , vol.178 , pp. 8127-8137
    • Eckle, T.1    Füllbier, L.2    Wehrmann, M.3
  • 15
    • 0348222661 scopus 로고    scopus 로고
    • Adenosine: An endogenous regulator of innate immunity
    • Haskó G, Cronstein BN: Adenosine: An endogenous regulator of innate immunity. Trends Immunol 2004; 25:33-39
    • (2004) Trends Immunol , vol.25 , pp. 33-39
    • Haskó, G.1    Cronstein, B.N.2
  • 16
    • 33646096475 scopus 로고    scopus 로고
    • Differential expression of adenosine receptors in human neutrophils: Up-regulation by specific Th1 cytokines and lipopolysaccharide
    • Fortin A, Harbour D, Fernandes M, et al: Differential expression of adenosine receptors in human neutrophils: Up-regulation by specific Th1 cytokines and lipopolysaccharide. J Leukoc Biol 2006; 79:574-585
    • (2006) J Leukoc Biol , vol.79 , pp. 574-585
    • Fortin, A.1    Harbour, D.2    Fernandes, M.3
  • 17
    • 33847054264 scopus 로고    scopus 로고
    • Attenuation of reperfusion lung injury and apoptosis by A2A adenosine receptor activation is associated with modulation of Bcl-2 and Bax expression and activation of extracellular signal-regulated kinases
    • Rivo J, Zeira E, Galun E, et al: Attenuation of reperfusion lung injury and apoptosis by A2A adenosine receptor activation is associated with modulation of Bcl-2 and Bax expression and activation of extracellular signal-regulated kinases. Shock 2007; 27:266-273
    • (2007) Shock , vol.27 , pp. 266-273
    • Rivo, J.1    Zeira, E.2    Galun, E.3
  • 18
    • 20144389389 scopus 로고    scopus 로고
    • Adenosine A2A receptor agonist improves cardiac dysfunction from pulmonary ischemia-reperfusion injury
    • Reece TB, Laubach VE, Tribble CG, et al: Adenosine A2A receptor agonist improves cardiac dysfunction from pulmonary ischemia-reperfusion injury. Ann Thorac Surg 2005; 79:1189-1195
    • (2005) Ann Thorac Surg , vol.79 , pp. 1189-1195
    • Reece, T.B.1    Laubach, V.E.2    Tribble, C.G.3
  • 19
    • 0035041314 scopus 로고    scopus 로고
    • Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model
    • McPherson JA, Barringhaus KG, Bishop GG, et al: Adenosine A(2A) receptor stimulation reduces inflammation and neointimal growth in a murine carotid ligation model. Arterioscler Thromb Vasc Biol 2001; 21: 791-796
    • (2001) Arterioscler Thromb Vasc Biol , vol.21 , pp. 791-796
    • McPherson, J.A.1    Barringhaus, K.G.2    Bishop, G.G.3
  • 20
    • 34548790244 scopus 로고    scopus 로고
    • Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury
    • Reutershan J, Cagnina RE, Chang D, et al: Therapeutic anti-inflammatory effects of myeloid cell adenosine receptor A2a stimulation in lipopolysaccharide-induced lung injury. J Immunol 2007; 179:1254-1263
    • (2007) J Immunol , vol.179 , pp. 1254-1263
    • Reutershan, J.1    Cagnina, R.E.2    Chang, D.3
  • 21
    • 0032589411 scopus 로고    scopus 로고
    • Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: Synergy with the type IV phosphodiesterase inhibitor, rolipram
    • Sullivan GW, Linden J, Buster BL, et al: Neutrophil A2A adenosine receptor inhibits inflammation in a rat model of meningitis: Synergy with the type IV phosphodiesterase inhibitor, rolipram. J Infect Dis 1999; 180: 1550-1560
    • (1999) J Infect Dis , vol.180 , pp. 1550-1560
    • Sullivan, G.W.1    Linden, J.2    Buster, B.L.3
  • 22
    • 40849140995 scopus 로고    scopus 로고
    • Effects of PEEP levels following repeated recruitment maneuvers on ventilator-induced lung injury
    • Ko SC, Zhang H, Haitsma JJ, et al: Effects of PEEP levels following repeated recruitment maneuvers on ventilator-induced lung injury. Acta Anaesthesiol Scand 2008; 52: 514-521
    • (2008) Acta Anaesthesiol Scand , vol.52 , pp. 514-521
    • Ko, S.C.1    Zhang, H.2    Haitsma, J.J.3
  • 23
    • 84940815279 scopus 로고
    • The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart
    • Drury AN, Szent-Györgyi A: The physiological activity of adenine compounds with especial reference to their action upon the mammalian heart. J Physiol 1929; 68:213-237
    • (1929) J Physiol , vol.68 , pp. 213-237
    • Drury, A.N.1    Szent-Györgyi, A.2
  • 24
    • 0023228683 scopus 로고
    • Adenosine in hemorrhagic shock: Possible role in attenuating sympathetic activation
    • Tung CS, Chu KM, Tseng CJ, et al: Adenosine in hemorrhagic shock: Possible role in attenuating sympathetic activation. Life Sci 1987; 41:1375-1382
    • (1987) Life Sci , vol.41 , pp. 1375-1382
    • Tung, C.S.1    Chu, K.M.2    Tseng, C.J.3
  • 25
    • 1342264245 scopus 로고    scopus 로고
    • Immunomodulatory and neuroprotective effects of inosine
    • Haskó G, Sitkovsky MV, Szabo C: Immunomodulatory and neuroprotective effects of inosine. Trends Pharmacol Sci 2004; 25: 152-157
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 152-157
    • Haskó, G.1    Sitkovsky, M.V.2    Szabo, C.3
  • 26
    • 33644778637 scopus 로고    scopus 로고
    • Adenosine in the airways: Implications and applications
    • Spicuzza L, Di Maria G, Polosa R: Adenosine in the airways: Implications and applications. Eur J Pharmacol 2006; 533:77-88
    • (2006) Eur J Pharmacol , vol.533 , pp. 77-88
    • Spicuzza, L.1    Di Maria, G.2    Polosa, R.3
  • 27
    • 55849114101 scopus 로고    scopus 로고
    • A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice
    • Eckle T, Grenz A, Laucher S, et al: A2B adenosine receptor signaling attenuates acute lung injury by enhancing alveolar fluid clearance in mice. J Clin Invest 2008; 118: 3301-3315
    • (2008) J Clin Invest , vol.118 , pp. 3301-3315
    • Eckle, T.1    Grenz, A.2    Laucher, S.3
  • 28
    • 0030981335 scopus 로고    scopus 로고
    • Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model
    • Tremblay L, Valenza F, Ribeiro SP, et al: Injurious ventilatory strategies increase cytokines and c-fos m-RNA expression in an isolated rat lung model. J Clin Invest 1997; 99:944-952
    • (1997) J Clin Invest , vol.99 , pp. 944-952
    • Tremblay, L.1    Valenza, F.2    Ribeiro, S.P.3
  • 29
    • 0345436055 scopus 로고    scopus 로고
    • Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: A randomized controlled trial
    • Ranieri VM, Suter PM, Tortorella C, et al: Effect of mechanical ventilation on inflammatory mediators in patients with acute respiratory distress syndrome: A randomized controlled trial. JAMA 1999; 282:54-61
    • (1999) JAMA , vol.282 , pp. 54-61
    • Ranieri, V.M.1    Suter, P.M.2    Tortorella, C.3
  • 30
    • 0036348490 scopus 로고    scopus 로고
    • Injurious ventilation induces widespread pulmonary epithelial expression of tumor necrosis factor-alpha and interleukin-6 messenger RNA
    • Tremblay LN, Miatto D, Hamid Q, et al: Injurious ventilation induces widespread pulmonary epithelial expression of tumor necrosis factor-alpha and interleukin-6 messenger RNA. Crit Care Med 2002; 30:1693-1700
    • (2002) Crit Care Med , vol.30 , pp. 1693-1700
    • Tremblay, L.N.1    Miatto, D.2    Hamid, Q.3
  • 31
    • 0030905548 scopus 로고    scopus 로고
    • Infections and the inflammatory response in acute respiratory distress syndrome
    • Headley AS, Tolley E, Meduri GU: Infections and the inflammatory response in acute respiratory distress syndrome. Chest 1997; 111:1306-1321
    • (1997) Chest , vol.111 , pp. 1306-1321
    • Headley, A.S.1    Tolley, E.2    Meduri, G.U.3
  • 32
    • 0343893748 scopus 로고    scopus 로고
    • Ventilation with lower tidal as compared with traditional tidal for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000; 342: 1301-1308
    • Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. The Acute Respiratory Distress Syndrome Network. N Engl J Med 2000; 342: 1301-1308
  • 33
    • 4444364798 scopus 로고    scopus 로고
    • Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation
    • Gajic O, Dara SI, Mendez JL, et al: Ventilator-associated lung injury in patients without acute lung injury at the onset of mechanical ventilation. Crit Care Med 2004; 32: 1817-1824
    • (2004) Crit Care Med , vol.32 , pp. 1817-1824
    • Gajic, O.1    Dara, S.I.2    Mendez, J.L.3
  • 34
    • 0348047537 scopus 로고    scopus 로고
    • The main function of IL-2 is to promote the development of T regulatory cells
    • Malek TR: The main function of IL-2 is to promote the development of T regulatory cells. J Leukoc Biol 2003; 74:961-965
    • (2003) J Leukoc Biol , vol.74 , pp. 961-965
    • Malek, T.R.1
  • 35
    • 0021720154 scopus 로고
    • Purified human granulocyte-macrophage colony-stimulating factor: Direct action on neutrophils
    • Gasson JC, Weisbart RH, Kaufman SE, et al: Purified human granulocyte-macrophage colony-stimulating factor: Direct action on neutrophils. Science 1984; 226:1339-1342
    • (1984) Science , vol.226 , pp. 1339-1342
    • Gasson, J.C.1    Weisbart, R.H.2    Kaufman, S.E.3
  • 36
    • 0034886012 scopus 로고    scopus 로고
    • Effects of granulocyte-macrophage colony stimulating factor (GM-CSF) in vivo on cytokine production and proliferation by spleen cells
    • Khatami S, Brummer E, Stevens DA: Effects of granulocyte-macrophage colony stimulating factor (GM-CSF) in vivo on cytokine production and proliferation by spleen cells. Clin Exp Immunol 2001; 125:198-201
    • (2001) Clin Exp Immunol , vol.125 , pp. 198-201
    • Khatami, S.1    Brummer, E.2    Stevens, D.A.3
  • 37
    • 0027961001 scopus 로고
    • Regulation of interleukin 10 release by tumor necrosis factor in humans and chimpanzees
    • Van der Poll T, Jansen J, Levi M, et al: Regulation of interleukin 10 release by tumor necrosis factor in humans and chimpanzees. J Exp Med 1994; 180:1985-1988
    • (1994) J Exp Med , vol.180 , pp. 1985-1988
    • Van der Poll, T.1    Jansen, J.2    Levi, M.3
  • 38
    • 28944445060 scopus 로고    scopus 로고
    • Biology of interleukin-10 and its regulatory roles in sepsis syndromes
    • Scumpia PO, Moldawer LL: Biology of interleukin-10 and its regulatory roles in sepsis syndromes. Crit Care Med 2005; 33: 468-471
    • (2005) Crit Care Med , vol.33 , pp. 468-471
    • Scumpia, P.O.1    Moldawer, L.L.2
  • 39
    • 0037394676 scopus 로고    scopus 로고
    • Neutrophils and acute lung injury
    • Abraham E: Neutrophils and acute lung injury. Crit Care Med 2003; 31:S195-S199
    • (2003) Crit Care Med , vol.31
    • Abraham, E.1
  • 40
    • 0035109852 scopus 로고    scopus 로고
    • Neutrophil activation and acute lung injury
    • Lee WL, Downey GP: Neutrophil activation and acute lung injury. Curr Opin Crit Care 2001; 7:1-7
    • (2001) Curr Opin Crit Care , vol.7 , pp. 1-7
    • Lee, W.L.1    Downey, G.P.2
  • 41
    • 1642579653 scopus 로고    scopus 로고
    • Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: Inhibition of chemokine induction
    • Day YJ, Marshall MA, Huang L, et al: Protection from ischemic liver injury by activation of A2A adenosine receptors during reperfusion: Inhibition of chemokine induction. Am J Physiol Gastrointest Liver Physiol 2004; 286:285-293
    • (2004) Am J Physiol Gastrointest Liver Physiol , vol.286 , pp. 285-293
    • Day, Y.J.1    Marshall, M.A.2    Huang, L.3
  • 42
    • 0033190943 scopus 로고    scopus 로고
    • Selective A2A adenosine receptor activation reduces ischemia-reperfusion injury in rat kidney
    • Okusa MD, Linden J, Macdonald T, et al: Selective A2A adenosine receptor activation reduces ischemia-reperfusion injury in rat kidney. Am J Physiol 1999; 277:404-412
    • (1999) Am J Physiol , vol.277 , pp. 404-412
    • Okusa, M.D.1    Linden, J.2    Macdonald, T.3
  • 43
    • 0042386007 scopus 로고    scopus 로고
    • Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: Role of ectonucleotidases and adenosine A2B receptors
    • Eltzschig HK, Ibla JC, Furuta GT, et al: Coordinated adenine nucleotide phosphohydrolysis and nucleoside signaling in posthypoxic endothelium: Role of ectonucleotidases and adenosine A2B receptors. J Exp Med 2003; 198:783-796
    • (2003) J Exp Med , vol.198 , pp. 783-796
    • Eltzschig, H.K.1    Ibla, J.C.2    Furuta, G.T.3


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