Cooperative binding of L-Trp to human tryptophan 2,3-dioxygenase: Resonance Raman spectroscopic analysis

Journal of Biochemistry

Volumn 145, Issue 4, 2009, Pages 505-515

  Fukumura, Eiko ^a,b   Sugimoto, Hiroshi ^a   Misumi, Yuko ^c   Ogura, Takashi ^c   Shiro, Yoshitsugu ^a  

^a Harima Institute ^*  (Japan)

^b OSAKA UNIVERSITY   (Japan)

^c UNIVERSITY OF HYOGO   (Japan)

Author keywords

Allosteric regulation; Heam; Raman spectra; Tryptophan

Indexed keywords

ENZYME; INDOLE; TRYPTOPHAN; TRYPTOPHAN 2,3 DIOXYGENASE; IRON; MUTANT PROTEIN; PROTEIN SUBUNIT; RECOMBINANT PROTEIN;

ABSORPTION SPECTROSCOPY; ARTICLE; CONFORMATIONAL TRANSITION; ENZYME ACTIVITY; HUMAN; MAMMAL; MUTANT; MUTATION; NONHUMAN; PROTEIN BINDING; RAMAN SPECTROMETRY; WILD TYPE; CHEMISTRY; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; PROTEIN SECONDARY STRUCTURE; XANTHOMONAS CAMPESTRIS;

BACTERIA (MICROORGANISMS); MAMMALIA;

CATALYTIC DOMAIN; HUMANS; IRON; KINETICS; MUTANT PROTEINS; MUTATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; RECOMBINANT PROTEINS; SPECTRUM ANALYSIS, RAMAN; SUBSTRATE SPECIFICITY; TRYPTOPHAN; TRYPTOPHAN OXYGENASE; XANTHOMONAS CAMPESTRIS;

EID: 67649660361     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvp002     Document Type: Article

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