Influence of the proportion of particulate autogenous bone graft/platelet-rich plasma on bone healing in critical-size defects. An immunohistochemical analysis in rat calvaria

Bone

Volumn 45, Issue 2, 2009, Pages 339-345

  Nagata, Maria ^a   Messora, Michel ^a   Okamoto, Roberta ^a   Campos, Natália ^a   Pola, Natália ^a   Esper, Luis ^a   Sbrana, Michyele ^a   Fucini, Stephen ^a,b   Garcia, Valdir ^a   Bosco, Alvaro ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b NONE

Author keywords

Bone regeneration; Growth factors; Immunohistochemistry; Osteoblasts; Platelets

Indexed keywords

OSTEOCALCIN; OSTEOPONTIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BONE DEFECT; BONE GRAFT; BONE REGENERATION; BONE TRANSPLANTATION; CALVARIA; CONTROLLED STUDY; FRACTURE HEALING; IMMUNOHISTOCHEMISTRY; MALE; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; THROMBOCYTE RICH PLASMA;

ANIMALS; BONE TRANSPLANTATION; IMMUNOHISTOCHEMISTRY; MALE; OSTEOCALCIN; OSTEOPONTIN; PARTICULATE MATTER; PLATELET COUNT; PLATELET-RICH PLASMA; RATS; RATS, WISTAR; SKULL; WOUND HEALING;

EID: 67649658037     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2009.04.246     Document Type: Article

References (33)

1. Marx R.E., Carlson E.R., Eichstaedt R.M., Schimmele S.R., Strauss J.E., and Georgeff K.R. Platelet-rich plasma: growth factor enhancement for bone grafts. Oral Surg. Oral Med. Oral. Pathol. Oral Radiol. 85 (1998) 638-646
2. Plachokova A.S., Nikolidakis D., Mulder J., Jansen J.A., and Creugers N.H. Effect of platelet-rich plasma on bone regeneration in dentistry: a systematic review. Clin. Oral Implants Res. 19 (2008) 539-545
3. Jakse N., Tangl S., Gilli R., Berghold A., Lorenzoni M., Eskici A., et al. Influence of PRP on autogenous sinus grafts. An experimental study on sheep. Clin. Oral Implants Res. 14 (2003) 578-583
4. Fennis J.P., Stoeling P.J., and Jansen J.A. Mandibular reconstruction: a histological and histomorphometric study on the use of autogenous scaffolds, particulate cortico-cancellous bone grafts and platelet rich plasma in goats. Int. J. Oral Maxillofac. Surg. 33 (2004) 48-55
5. Simon Z., and Friedlich J. The use of autogenous bone grafting with platelet-rich plasma for alveolar ridge reconstruction: a clinical report. J. Calif. Dent. Assoc. 34 (2006) 895-899
6. Messora M.R., Nagata M.J., Mariano R.C., Dornelles R.C., Bomfim S.R., Fucini S.E., et al. Bone healing in critical-size defects treated with platelet-rich plasma: a histologic and histometric study in rat calvaria. J. Periodontol. Res. 43 (2008) 217-223
7. Aghaloo T.L., Moy P.K., and Freymiller E.G. Investigation of platelet rich plasma in rabbit cranial defects: a pilot study. J. Oral. Maxillofac. Surg. 60 (2002) 1176-1181
8. Froum S.J., Wallace S.S., Tarnow D.P., and Cho S.C. Effect of platelet-rich plasma on bone growth and osseointegration in human maxillary sinus grafts: three bilateral case reports. Int. J. Periodontics Restorative Dent. 22 (2002) 45-53
9. Choi B.H., Im C.J., Huh J.Y., Suh J.J., and Lee S.H. Effect of platelet-rich plasma on bone regeneration in autogenous bone graft. Int. J. Oral Maxillofac. Surg. 33 (2004) 56-59
10. Gerard D., Carlson E.R., Gotcher J.E., and Jacobs M. Effects of platelet-rich plasma on the healing of autologous bone grafted mandibular defects in dogs. J. Oral Maxillofac. Surg. 64 (2006) 443-451
11. Choi B.H., Zhu S.J., Kim B.Y., Huh J.Y., Lee S.H., and Jung J.H. Effect of platelet-rich plasma (PRP) concentration on the viability and proliferation alveolar bone cells: an in vitro study. Int. J. Oral Maxillofac. Surg. 34 (2005) 420-424
12. Mazor Z., Peleg M., Garg A.K., and Luboshitz J. Platelet-rich plasma for bone graft enhancement in sinus floor augmentation with simultaneous implant placement: patient series study. Implant. Dent. 13 (2004) 65-72
13. Robiony M., Polini F., Costa F., and Politi M. Osteogenesis distraction and platelet-rich plasma for bone restoration of the severely atrophic mandible: preliminary results. J. Oral Maxillofac. Surg. 60 (2002) 630-635
14. Butterfield K.J., Bennett J., Gronowicz G., and Adams D. Effect of platelet-rich plasma with autogenous bone graft for maxillary sinus augmentation in a rabbit model. J. Oral Maxillofac. Surg. 63 (2005) 370-376
15. Thorwarth M., Rupprecht S., Falk S., Felszeghy E., Wiltfang J., and Schlegel K.A. Expression of bone matrix proteins during de novo bone formation using a bovine collagen and platelet-rich plasma (prp)-an immunohistochemical analysis. Biomaterials 26 (2005) 2575-2584
16. Graziani F., Ivanovski S., Cei S., Ducci F., Tonetti M., and Gabriele M. The in vitro effect of different PRP concentrations on osteoblasts and fibroblasts. Clin. Oral Implants Res. 17 (2006) 212-219
17. Thorwarth M., Wehrhan F., Schultze-Mosgau S., Wiltfang J., and Schlegel K.A. PRP modulates expression of bone matrix proteins in vivo without long-term effects on bone formation. Bone 38 (2006) 30-40
18. Wiltfang J., Kloss F.R., Kessler P., Nkenke E., Schultze-Mosgau S., Zimmermann R., et al. Effects of platelet-rich plasma on bone healing in combination with autogenous bone and bone substitutes in critical-size defects. An animal experiment. Clin. Oral Implants Res. 15 (2004) 187-193
19. Weibrich G., Kleis W.K., Hafner G., and Hitzler W.E. Growth factor levels in platelet-rich plasma and correlations with donor age, sex, and platelet count. J. Craniomaxillofac. Surg. 30 (2002) 97-102
20. Lacoste E., Martineau I., and Gagnon G. Platelet concentrates: effects of calcium and thrombin on endothelial cell proliferation and growth factor release. J. Periodontol. 74 (2003) 1498-1507
21. Martineau I., Lacoste E., and Gagnon G. Effects of calcium and thrombin on growth factor release from platelet concentrates: kinetics and regulation of endothelial cell proliferation. Biomaterials 25 (2004) 4489-4502
22. Liu W., Toyosawa S., Furuichi T., Kanatani N., Yoshida C., Liu Y., et al. Overexpression of Cbfa1 in osteoblasts inhibits osteoblast maturation and causes osteopenia with multiple fractures. J. Cell. Biol. 155 (2001) 157-166
23. Tsay R.C., Vo J., Burke A., Eisig S.B., Lu H.H., and Landesberg R. Differential growth factor retention by platelet-rich plasma composites. J. Oral Maxillofac. Surg. 63 (2005) 521-528
24. Lee H.W., Reddy M.S., Geurs N., Palcanis K.G., Lemons J.E., Rahemtulla F.G., et al. Efficacy of platelet-rich plasma on wound healing in rabbits. J. Periodontol. 79 (2008) 691-696
25. Stein G.S., and Lian J.B. Molecular mechanisms mediating proliferation/differentiation interrelationships during progressive development of the osteoblast phenotype. Endocr. Rev. 14 (1993) 424-442
26. Fréchette J.P., Martineau I., and Gagnon G. Platelet-rich plasmas: growth factor content and roles in wound healing. J. Dent. Res. 84 (2005) 434-439
27. Gruber R., Kandler B., Fischer M.B., and Watzek G. Osteogenic differentiation induced by bone morphogenetic proteins can be suppressed by platelet-released supernatant in vitro. Clin. Oral Implants Res. 17 (2006) 188-1893
28. Ogino Y., Ayukawa Y., Kukita T., and Koyano K. The contribution of platelet-derived growth factor, transforming growth factor-beta1, and insulin-like growth factor-I in platelet-rich plasma to the proliferation of osteoblast-like cells. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 101 (2006) 724-729
29. Gruber R., Karreth F., Fischer M.B., and Watzek G. Platelet-released supernatants stimulate formation of osteoclast-like cells through a prostaglandin/RANKL-dependent mechanism. Bone 30 (2002) 726-732
30. Albrektsson T. Repair of bone grafts. A vital microscopic and histological investigation in the rabbit. Scand. J. Plast. Reconstr. Surg. 14 (1980) 1-12
31. Goldberg V.M., and Stevenson S. The biology of bone grafts. Semin. Arthroplasty 4 (1993) 58-63
32. Pallesen L., Schou S., Aaboe M., Hjørting-Hansen E., Nattestad A., and Melsen F. Influence of particle size of autogenous bone grafts on the early stages of bone regeneration: a histologic and stereologic study in rabbit calvarium. Int. J. Oral Maxillofac. Implants 17 (2002) 498-506
33. Shapoff C.A., Bowers G.M., Levy B., Mellonig J.T., and Yukna R.A. The effect of particle size on the osteogenic activity of composite grafts of allogeneic freeze-dried bone and autogenous marrow. J. Periodontol. 51 (1980) 625-630