Synthesis of sialyl Lewisa (sLea, CA19-9) and construction of an immunogenic sLea vaccine

Cancer Immunology, Immunotherapy

Volumn 58, Issue 9, 2009, Pages 1397-1405

  Ragupathi, Govind ^a   Damani, Payal ^a   Srivastava, Geeta ^b   Srivastava, Om ^b   Sucheck, Steven J ^c   Ichikawa, Yoshi ^b   Livingston, Philip O ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b Optimer Pharmaceuticals Inc   (United States)

^c UNIVERSITY OF TOLEDO   (United States)

Author keywords

CA19 9; Cancer vaccine; Carbohydrate conjugate vaccine; Sialyl Lewisa

Indexed keywords

CA 19-9 ANTIGEN; CANCER VACCINE; GPI 0100; HUMAN SERUM ALBUMIN; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; IMMUNOLOGICAL ADJUVANT; KEYHOLE LIMPET HEMOCYANIN; SIALYL LEWIS A ANTIGEN KEYHOLE LIMPET HEMOCYANIN CONJUGATE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY TITER; ARTICLE; CANCER CELL CULTURE; COMPLEMENT DEPENDENT CYTOTOXICITY; CONTROLLED STUDY; CROSS REACTION; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IMMUNOGENICITY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ADENOCARCINOMA; ANIMALS; CANCER VACCINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HEMOCYANIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; LEWIS BLOOD-GROUP SYSTEM; LUNG NEOPLASMS; MICE; MICE, INBRED C57BL; SAPONINS; SMALL CELL LUNG CARCINOMA; VACCINES, CONJUGATE;

EID: 67649647747     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-008-0654-7     Document Type: Article

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