A portable and autonomous magnetic detection platform for biosensing

Sensors

Volumn 9, Issue 6, 2009, Pages 4119-4137

  Germano, José ^a   Martins, Verónica C ^b   Cardoso, Filipe A ^b   Almeida, Teresa M ^a,b   Sousa, Leonel ^a,b   Freitas, Paulo P ^b   Piedade, Moisés S ^a,b  

^a INESC   (Portugal)

^b INSTITUTO SUPERIOR TÉCNICO   (Portugal)

Author keywords

Biomolecular recognition detection; Digital signal processing; Lab on chip; Magnetic nanoparticles; Magnetoresistive sensors; Portable platform

Indexed keywords

BIOMOLECULAR RECOGNITION; LAB-ON-CHIP; MAGNETIC NANO-PARTICLES; MAGNETO RESISTIVE SENSORS; PORTABLE PLATFORM;

ASSAYS; BIOCHIPS; DIGITAL SIGNAL PROCESSING; GRAPHICAL USER INTERFACES; MOLECULAR RECOGNITION; NANOPARTICLES;

SIGNAL DETECTION;

EID: 67649610447     PISSN: 14248220     EISSN: None     Source Type: Journal    
DOI: 10.3390/s90604119     Document Type: Article

References (23)

1. Geschke, O.; Klank, H.; Telleman, P., editors. Microsystems Engineering of Lab-on-a-chip Devices. Wiley-VCH Verlag GmbH & Co. KgaA: Weinheim, Germany, 2004.
2. Baselt, D.R.; Lee G.U.; Natesan, M.; Metzger, S.W.; Sheehan, P.E.; Colton, R.J. A biosensor based on magnetoresistance technology. Biosens. Bioelectron. 1998, 13, 731-739.
3. Graham, D. L.; Ferreira, H. A.; Freitas, P. P. Magnetoresistive-based biosensors and biochips: a review. Trends Biotechnol. 2004, 22, 455-462.
4. Brückl, H.; Panhorst, M.; Schotter, J.; Kamp, P. B.; Becker, A. Magnetic particles as markers and carriers of biomolecules. IEE Proc.-Nanobiotechnol 2005, 152, 41-46.
5. Wang, S. X.; Guanxiong, L. Advances in giant magnetoresistance biosensors with magnetic nanoparticle Tags: review and outlook. IEEE Trans. Magn. 2008, 44, 1687-1702.
6. Piedade, M.; Sousa, L. A.; de Almeida, T. M.; Germano, J.; da Costa, B. A.; Lemos, J. M.; Freitas, P. P.; Ferreira, H. A.; Cardoso, F. A. A new hand-held microsystem architecture for biological analysis. IEEE Trans. Circuits Syst. Regul. Pap. 2006, 53, 2384-2395.
7. Schotter, J.; Kamp, P. B.; Becker, A.; Pühler, A.; Reiss, G.; Brückl, H. Comparison of a prototype magnetoresistive biosensor to standard fluorescent DNA detection. Biosens. Bioelectron. 2004, 19, 1149 - 1156.
8. de Boer, B. M.; Kahlman, J. A. H. M.; Jansen, T. P. G. H.; Duric, H.; Veen, J. An integrated and sensitive detection platform for magneto-resistive biosensors. Biosens. Bioelectron. 2007, 22, 2366 - 2370.
9. Han, S.-J.; Xu, L.; Yu, H.; Wilson, R. J.; White, R. L.; Pourmand, N.; Wang, S. X. CMOS Integrated DNA Microarray Based on GMR Sensors. In Proceedings of IEEE International Electron Devices Meeting (IEDM), San Francisco, CA, USA, December 11-13, 2006; pp.1-4.
10. Tamanaha, C. R.; Mulvaney, S. P.; Rife, J. C.; Whitman, L. J. Magnetic labeling, detection, and system integration. Biosens. Bioelectron. 2008, 24, 1-13.
11. Shen, W.; Schrag, B. D.; Carter, M. J.; Xie, J.; Xu, C.; Sun, S.; Xiao, G. Detection of DNA labeled with magnetic nanoparticles using MgO-based magnetic tunnel junction sensors. J. Appl. Phys. 2008, 103, 07A306.
12. Freitas, P. P.; Ferreira, H. A.; Graham, D. L.; Clarke, L. A.; Amaral, M. D.; Martins, V.; Fonseca, L.; Cabral, J. S. Magnetoresistive DNA chips. Magnetoelectronics, Johnson M., Ed.; Elsevier Inc.: Oxford, UK, 2004; pp. 331 - 374.
13. Cardoso, F. A.; Ferreira, H. A.; Conde, J. P.; Freitas, P. P.; Vidal, D.; Germano, J.; Sousa, L.; Piedade, M. S.; Costa, B. A.; Lemos, J. M. Diode magnetic tunnel junction cell for fully scalable matrix-based biochip. J. Appl. Phys. 2006, 99, 08B307.
14. Cho, Y.-K.; Kim, S.; Kim, Y. A.; Lim, H. K.; Lee, K.; Yoon, D.; Lim, G.; Pak, Y. E.; Ha, T. H.; Kim, K. Characterization of DNA immobilization and subsequent hybridization using in situ quartz crystal microbalance, fluorescence spectroscopy, and surface plasmon resonance. J. Colloid Interface Sci. 2004, 278, 44 - 52.
15. Sousa, R. C.; Freitas, P. P.; Chu, V.; Conde, J. P. Vertical integration of a spin dependent tunnel junction with an amorphous Si diode for MRAM application. IEEE Trans. Magn. 1999, 35, 2832-2834.
16. Cardoso, F. A.; Germano, J.; Ferreira, R.; Cardoso, S.; Martins, V. C.; Freitas, P. P.; Piedade, M. S.; Sousa, L. Detection of 130 nm magnetic particles by a portable electronic platform using spin valve and magnetic tunnel junction sensors. J. Appl. Phys. 2008, 103, 07A310.
17. Cardoso, F. A.; Ferreira, R.; Cardoso, S.; Conde, J. P.; Chu, V.; Freitas, P. P.; Germano, J.; Almeida, T.; Sousa, L.; Piedade, M. S. Noise characteristics and particle detection limits in diode+MTJ matrix elements for biochip applications. IEEE Trans. Magn. 2007, 43, 2403-2405.
18. Almeida, T. M.; Piedade, M. S.; Sousa, L.; Germano, J.; Lopes, P. A. C.; Cardoso, F. A.; Freitas, P. P. On the modelling of new tunnel junction magnetoresisitive biosensors. IEEE Trans. Instrum. Meas. 2009. in press.
19. Stallings W. Cryptography and Network Security: Principles and Practices. Prentice Hall, Inc.: New Jersey, USA, 2006.
20. Ferreira, H. A.; Cardoso, F. A.; Ferreira, R.; Cardoso, S.; Freitas, P. P. Magnetoresistive DNA chips based on ac field focusing of magnetic labels. J. Appl. Phys. 2006, 99, 08P105.
21. Conn, R. A brief dive into. NET. In Proceedings of the 43rd Annual Southeast Regional Conference, Kennesaw, GA, USA, 2005; pp.21-22.
22. Lopes, P. A. C.; Germano, J.; Almeida, T. M.; Sousa, L.; Piedade, M. S.; Cardoso, F. A.; Ferreira, H. A.; Freitas, P. P. Measuring and extraction of biological information on new handheld biochipbased microsystem. IEEE Trans. Instrum. Meas. 2009. in press.
23. Martins, V. C.; Cardoso, F. A.; Germano, J.; Cardoso, S.; Sousa, L.; Piedade, M.; Freitas, P. P.; Fonseca, L. P. Femtomolar limit of detection with a magnetoresistive biochip. Biosens. Bioelectron. 2009, 24, 2690 - 2695.