Cholinergic agonists may produce preservation of myocardial ischaemia/reperfusion injury

Medical Hypotheses

Volumn 73, Issue 3, 2009, Pages 312-314

  Xiong, J ^a   Xue, F S ^a   Xu, Y C ^a   Yang, Q Y ^a   Liao, X ^a   Wang, W L ^a  

^a PLASTIC SURGERY HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

3 (2,4 DIMETHOXYBENZYLIDENE)ANABASEINE; ACETYLCHOLINE; CHOLINE; CHOLINERGIC RECEPTOR STIMULATING AGENT; CYCLOOXYGENASE 2; GLYCOGEN SYNTHASE KINASE 3BETA; HIGH MOBILITY GROUP B1 PROTEIN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERSTITIAL COLLAGENASE; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NICOTINE; NICOTINIC RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; PLACEBO; PROSTAGLANDIN E2; PROTEIN KINASE B; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TRANSCRIPTION FACTOR REL; TUMOR NECROSIS FACTOR; TUMOR NECROSIS FACTOR RECEPTOR;

ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHOLINERGIC TRANSMISSION; CYTOKINE RELEASE; HEART FAILURE; HEART INFARCTION PREVENTION; HEART MUSCLE ISCHEMIA; HEART PROTECTION; HUMAN; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REPERFUSION INJURY; SEPSIS; SIGNAL TRANSDUCTION; VAGUS NERVE; VAGUS NERVE STIMULATION;

ANIMALS; CHOLINERGIC AGONISTS; CYTOKINES; HUMANS; MODELS, CARDIOVASCULAR; MODELS, IMMUNOLOGICAL; MYOCARDIUM; RECEPTORS, CHOLINERGIC; REPERFUSION INJURY;

EID: 67649603945     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mehy.2009.03.026     Document Type: Article

References (40)

1. Taylor D.A., and Zenovich A.G. Cardiovascular cell therapy and endogenous repair. Diabetes Obes Metab 10 (2008) 5-15
2. White H.D., and Chew D.P. Acute myocardial infarction. Lancet 372 (2008) 570-584
3. Hearse D.J. Reperfusion of the ischemic myocardium. J Mol Cell Cardiol 9 (1977) 605-616
4. Murry C.E., Jenings R.B., and Reimer K.A. Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74 (1986) 1124-1136
5. Gao F., Yan W.L., Geng Y.J., Cai Z.J., Zhu M.Z., Zang Y.M., et al. "Hypoxic postconditioning" protecting cardiac myocyte from hypoxia/reoxygenation injury in adult rats. Chin Heart J 11 (1999) 241-243
6. Gross E.R., and Gross G.J. Ligand triggers of classical preconditioning and postconditioning. Cardiovasc Res 70 (2006) 212-221
7. de Perrot M., Liu M., Waddell T.K., and Keshavjee S. Ischemia-reperfusion-induced Lung Injury. Am J Respir Crit Care Med 167 (2003) 490-511
8. Morariu A.M., Loef B.G., Aarts L.P., Rietman G.W., Rakhorst G., van Oeveren W., et al. Dexamethasone: benefit and prejudice for patients undergoing on-pump coronary artery bypass grafting. Chest 128 (2005) 2677-2687
9. Pavlov V.A., Parrish W.R., Rosas-Ballina M., Ochani M., Puerta M., Ochani K., et al. Brain acetycholinesterase activity controls systemic cytokines levels through the cholinergic anti-inflammatory pathway. Brain Behav Immun 23 (2009) 41-45
10. Pavlov V.A. Cholinergic modulation of inflammation. Int J Clin Exp Med 1 (2008) 203-212
11. Wang H., Yu M., Ochani M., Amella C.A., Tanovic M., Susarla S., et al. Nicotinic acetylcholine receptor alpha7 subunit is an essential regulator of inflammation. Nature 421 (2003) 384-388
12. Moccia F., Frost C., Berra-Romani R., Tanzi F., Adams D.J., et al. Expression and function of neuronal nicotinic acetylcholine receptors in rat microvascular endothelial cells. Am J Physiol Heart Circ Physiol 286 (2004) H486-H491
13. Yeboah M.M., Xue X., Duan B., Ochani M., Tracey K.J., Susin M., et al. Cholinergic agonists attenuate renal ischemia-reperfusion injury in rat. Kidney Int 74 (2008) 62-69
14. Wang H., Liao H., Ochani M., Justiniani M., Lin X., Yang L., et al. Cholinegic agonists inhibit HMGB-1 release and improve survival in experimental sepsis. Nat Med 10 (2004) 1216-1221
15. Wittebole X., Hahm S., Coyle S.M., Kumar A., Calvano S.E., and Lowry S.F. Nicotine exposure alters in vivo human responses to endotoxin. Clin Exp Immunol 147 (2007) 28-34
16. Saeed R.W., Varma S., Peng-Nemeroff T., Sherry B., Balakhaneh D., Huston J., et al. Cholinergic stimulation blocks endothelial cell activation and leukocyte recruitment during inflammation. J Exp Med 201 (2005) 1113-1123
17. Sadis C., Teske G., Stokman G., Kubjak C., Claessen N., Moore F., et al. Nicotine protects kidney from renal ischemia/reperfusion injury through the cholinergic anti-inflammatory pathway. PLoS ONE 2 (2007) e469
18. Parrish W.R., Rosas-Ballina M., Gallowitsch-Puerta M., Ochani M., Ochani K., Yang L.H., et al. Modulation of TNF release by choline requires a{cyrillic}7 subunit nicotinic acetylcholine receptor-mediated signaling. Mol Med 14 (2008) 567-574
19. Huston J.M., Gallowitsch-Puerta M., Ochani M., Ochani K., Yuan R., Rosas-Ballina M., et al. Transcutaneous vagus nerve stimulation reduces serum high mobility group box 1 levels and improve survival in murine sepsis. Crit Care Med 35 (2007) 2762-2768
20. Ying S.Q., Fang L., Xiang M.X., Xu G., Shan J., and Wang J.A. Protective effects of magnesium against ischemia-reperfusion injury through inhibition of P-selectin in rats. Clin Exp Pharmacol Physiol 34 (2007) 1234-1239
21. Giebelen I.A., van Westerloo D.J., LaRosa G.J., de Vos A.F., and van der Poll T. Stimulation of α7 cholinergic receptors inhibits lipopolysaccharide-induced neutrophil recruitment by a tumor necrosis factor α-impendent mechanism. Shock 27 (2007) 443-447
22. Henson P.M., Bratton D.L., and Fadok V.A. The phosphatidylserine receptor: a crucial molecular switch?. Nat Rev Mol Cell Biol 2 (2001) 627-633
23. 2 in rat microglial cultures. J Neuroinflammation 2 (2005) 4
24. Li M., Zheng C., Sato T., Kawada T., Sugimachi M., and Sunagawa K. Vagal nerve stimulation markedly improves long-term survival after chronic heart failure in rats. Circulation 109 (2004) 120-124
25. Squire I.B., Evans J., Ng L.L., Loftus I.M., and Thompson M.M. Plasma MMP-9 and MMP-2 following acute myocardial infarction in man: correlation with echocardiographic and neurohumoral parameters of left ventricular dysfunction. J Card Fail 10 (2004) 328-333
26. Webb C.S., Bonnema D.D., Ahmed S.H., Leonardi A.H., McClure C.D., Clark L.L., et al. Specific temporal profile of matrix metalloproteinase release occurs in patients after myocardial infarction relation to left ventricular remodeling. Circulation 114 (2006) 1020-1027
27. Uemura K., Li M., Tsutsumi T., Yamazaki T., Kawada T., Kamiya A., et al. Efferent vagal nerve stimulation induces tissue inhibitor of metalloproteinase-1 in myocardial ischemia-reperfusion injury in rabbit. Am J Physiol Heart Circ Physiol 293 (2007) H2254-H2261
28. Tsang A., Hausenloy D.J., Mocanu M.M., and Yellon D.M. Postconditioning: a form of "modified reperfusion" protects the myocardium by activating the phosphatidylinositol 3-Kinase-Akt pathway. Circ Res 95 (2004) 230-232
29. Zang W.J., Sun L., and Yu X.J. Cardioprotection of ischemic postconditioning and pharmacological post-treatment with adenosine or acetylcholine. Sheng Li Xue Bao 59 (2007) 593-600
30. Jope R.S., Yuskaitis C.J., and Beurel E. Glycogen synthase kinase-3 (GSK3): inflammation, diseases, and therapeutics. Neurochem Res 32 (2007) 577-595
31. Gao H.K., Yin Z., Zhou N., Feng X.Y., Gao F., and Wang H.C. Glycogen synthase kinase 3 inhibition protects the heart from acute ischemia-reperfusion injury via inhibition of inflammation and apoptosis. J Cardiovasc Pharmacol 52 (2008) 286-292
32. Kakinuma Y., Ando M., Kuwabara M., Katare R.G., Okudela K., Kobayashi M., et al. Acetylcholine from vagal stimulation protects cardiomyocytes against ischemia and hypoxia involving additive non-hypoxic induction of HIF-1a. FEBS Lett 579 (2005) 2111-2118
33. Zang W.J., Sun L., Yu X.J., Lv J., Chen L.N., and Liu B.H. Vagal control of cardiac function and vagal protection of ischemic myocardium. Sheng Li Xue Bao 60 (2008) 443-452
34. Sun Y.L., Hu S.J., Wang L.H., Hu Y., and Zhou J.Y. Comparison of low and high doses of Carvedilol on restoration of cardiac function and calcium-handling proteins in rat failing heart. Clin Exp Pharmacol Physiol 32 (2005) 553-560
35. Sadis C., Teske G., Stokman G., Kubjak C., Claessen N., Moore F., et al. Nicotine protects kidney from renal ischemia/reperfusion injury through the cholinergic anti-inflammatory pathway. PLoS ONE 2 (2007) 469
36. Crockett E.T., Galligan J.J., Uhal B.D., Harkema J., Roth R., and Pandya K. Protection of early phase hepatic ischemia-reperfusion injury by cholinergic agonists. BMC Clin Pathol 6 (2006) 3
37. Wu R., Dong W., Ji Y., Zhou M., Marini C.P., Ravikumar T.S., et al. Orexigenic hormone ghrelin attenuates local and remote organ injury after intestinal ischemia-reperfusion. PLoS ONE 3 (2008) e2026
38. Castro R.R., Porphirio G., Serra S.M., and Nóbrega A.C. Cholinergic stimulation with pyridostigmine protects against exercise induced myocardial ischaemia. Heart 90 (2004) 1119-1123
39. Schwartz P.J., De Ferrari G.M., Sanzo A., Landolina M., Rordorf R., Raineri C., et al. Long term vagal stimulation in patients with advanced heart failure: first experience in man. Eur J Heart Fail 10 (2008) 884-891
40. Azuma J., and Nonen S. Chronic heart failure: β-blockers and pharmacogenetics. Eur J Clin Pharmacol 65 (2009) 3-17