Ketoprofen in topical formulation decreases the matrix metalloproteinase-2 expression and pulmonary metastatic incidence in nude mice with osteosarcoma

Journal of Orthopaedic Research

Volumn 27, Issue 7, 2009, Pages 909-915

  Kamei, Setsuya ^a,b   Sakayama, Kenshi ^a   Tamashiro, Shinta ^b   Aizawa, Junichi ^a,b   Miyawaki, Joji ^a,b   Miyazaki, Tatsuhiko ^a   Yamamoto, Haruyasu ^a   Norimatsu, Yoshiaki ^b   Masuno, Hiroshi ^b  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b EHIME PREFECTURAL UNIVERSITY OF HEALTH SCIENCES   (Japan)

Author keywords

Ketoprofen; Matrix metalloproteinase 2; Osteosarcoma; Pulmonary metastasis

Indexed keywords

CD34 ANTIBODY; CYCLINE; DEOXYURIDINE TRIPHOSPHATE PYROPHOSPHATASE; GELATINASE A; KETOPROFEN; PLACEBO; VASCULOTROPIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INCIDENCE; CONTROLLED STUDY; DRUG EFFECT; DRUG FORMULATION; IMMUNOHISTOCHEMISTRY; LUNG METASTASIS; MALE; NICK END LABELING; NONHUMAN; OSTEOSARCOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; SURVIVAL RATE; TUMOR GROWTH;

ADMINISTRATION, TOPICAL; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTIGENS, CD34; APOPTOSIS; CELL LINE, TUMOR; IN SITU NICK-END LABELING; INCIDENCE; KETOPROFEN; LUNG NEOPLASMS; MALE; MATRIX METALLOPROTEINASE 2; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NEOVASCULARIZATION, PATHOLOGIC; OSTEOSARCOMA; SURVIVAL RATE; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 67649600831     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1002/jor.20832     Document Type: Article

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