The role of intraoperative bone marrow aspirate stem cell concentration as a bone grafting technique

Techniques in Foot and Ankle Surgery

Volumn 7, Issue 2, 2008, Pages 84-89

  Jacobsen, Kimberly ^a   Szczepanowski, Karolynn ^a   Al Zube, Loay A ^a   Kim, J ^a   Lin, Sheldon S ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Cellect; Graft matrix; Mesenchymal stem cell; Nonunions; Selective cell retention (SCR)

Indexed keywords

BONE MORPHOGENETIC PROTEIN; CALCIUM PHOSPHATE CERAMIC; CELL MARKER; DNA; HEPARIN; MOLECULAR MARKER; PLATELET DERIVED GROWTH FACTOR;

ARTHRODESIS; AUTOLOGOUS BONE MARROW TRANSPLANTATION; AVASCULAR NECROSIS; BONE DEMINERALIZATION; BONE MARROW; BONE MARROW BIOPSY; BONE MATRIX; CELL ISOLATION; DISEASE TRANSMISSION; FIXATION DEVICE; FOLLOW UP; FRACTURE HEALING; GRAFT REJECTION; GROWTH PLATE; HEMATOPOIETIC STEM CELL; HUMAN; INTRAOPERATIVE PERIOD; METABOLIC BONE DISEASE; OSTEOLYSIS; POSTMENOPAUSE OSTEOPOROSIS; POSTOPERATIVE CARE; PREOPERATIVE CARE; PRIORITY JOURNAL; REVIEW; THROMBOCYTE RICH PLASMA; THROMBOCYTOPENIA; TREATMENT CONTRAINDICATION; TREATMENT INDICATION; TREATMENT PLANNING;

EID: 67649580466     PISSN: 15360644     EISSN: 15381943     Source Type: Journal    
DOI: 10.1097/btf.0b013e318175ccba     Document Type: Review

References (14)

1. Sen MK, Miclau T. Autologous iliac crest bone graft: should it still be the gold standard for treating nonunions? Injury. 2007;38(Suppl 1):S75-S80.
2. Gupta AR. Perioperative and long-term complications of iliac crest bone graft harvesting for spinal surgery: a quantitative review of the literature. Int Med J. 2001;8:163-166.
3. Kraus KH, Kirker-Head C. Mesenchymal stem cells and bone regeneration. Vet Surg. 2006;35:232-242.
4. Bruder SP, Jaiswal N, Ricalton NS, et al. Mesenchymal stem cells in osteobiology and applied bone regeneration. Clin Orthop Relat Res. 1998;355 Suppl:S247-S256.
5. Arinzeh TL, Peter SJ, Archambault MP, et al. Allogenic mesenchymal stem cell regenerate bone in a critical-sized canine segmental defect. J Bone Joint Surg Am. 2003;85A:1927-1935.
6. Brodke D, Pedrozo HA, Kapur TA, et al. Bone grafts prepared with selective cell retention technology heal canine segmental defects as effectively as autograft. J Orthop Res. 2006;24(5):857-866.
7. Bruder SP, Kraus K, Goldberg V, et al. The effect of implants loaded with autologous mesenchymal stem cells on the healing of canine segmental bone defects. J Bone Joint Surg Am. 1998;80A:985-996.
8. Fleming JE, Muschler GF. The cell biology of bone tissue engineering. Semin Arthroplasty. 2002;13:143-157.
9. Muschler GF, Nitto H, Matsukura Y, et al. Spine fusion using cell matrix composites enriched in bone marrow derived cells. Clin Orthop. 2003;407:102-118.
10. Cellect®-Cell Capture Technology. DePuy, Johnson & Johnson Company. 2005-2006.
11. Quarto R, Thomas D, Liang CT. Bone progenitor cell deficits and the age-associated decline in bone repair capacity. Calcif Tissue Int. 1995;56:123-129.
12. Muschler GF, Nitto H, Boehm CA, et al. Age- and gender-related change In the cellularity of human bone marrow and the prevalence of osteoblastic progenitors. J Orthop Res. 2001;19:117-125.
13. Hernigou P, Beaujean F. Abnormalities in the bone marrow of the iliac crest in patients who have osteonecrosis secondary to corticosteroid therapy or alcohol abuse. J Bone Joint Surg Am. 1997;79:1047-1053.
14. Macey LR, Kana SM, Jingushi S, et al. Defects of early fracture-healing in experimental diabetes. J Bone Joint Surg Am. 1989;71:722-733.